PreprintArticleVersion 1Preserved in Portico This version is not peer-reviewed
Virtual Rapid Sensing of COVID 19 Antibodies In Vivo against Negative Patient Serum Using Human DNA Immobilized Synthetic Artificial Skin Tattoo Low Cost Chemosens
Version 1
: Received: 25 August 2024 / Approved: 25 August 2024 / Online: 26 August 2024 (17:06:02 CEST)
How to cite:
Lee, K.; Ly, S. Y.; Oh, Y.; Jun, S.; Kim, D. H. Virtual Rapid Sensing of COVID 19 Antibodies In Vivo against Negative Patient Serum Using Human DNA Immobilized Synthetic Artificial Skin Tattoo Low Cost Chemosens. Preprints2024, 2024081782. https://doi.org/10.20944/preprints202408.1782.v1
Lee, K.; Ly, S. Y.; Oh, Y.; Jun, S.; Kim, D. H. Virtual Rapid Sensing of COVID 19 Antibodies In Vivo against Negative Patient Serum Using Human DNA Immobilized Synthetic Artificial Skin Tattoo Low Cost Chemosens. Preprints 2024, 2024081782. https://doi.org/10.20944/preprints202408.1782.v1
Lee, K.; Ly, S. Y.; Oh, Y.; Jun, S.; Kim, D. H. Virtual Rapid Sensing of COVID 19 Antibodies In Vivo against Negative Patient Serum Using Human DNA Immobilized Synthetic Artificial Skin Tattoo Low Cost Chemosens. Preprints2024, 2024081782. https://doi.org/10.20944/preprints202408.1782.v1
APA Style
Lee, K., Ly, S. Y., Oh, Y., Jun, S., & Kim, D. H. (2024). Virtual Rapid Sensing of COVID 19 Antibodies In Vivo against Negative Patient Serum Using Human DNA Immobilized Synthetic Artificial Skin Tattoo Low Cost Chemosens. Preprints. https://doi.org/10.20944/preprints202408.1782.v1
Chicago/Turabian Style
Lee, K., Sihyun Jun and Dong Ho Kim. 2024 "Virtual Rapid Sensing of COVID 19 Antibodies In Vivo against Negative Patient Serum Using Human DNA Immobilized Synthetic Artificial Skin Tattoo Low Cost Chemosens" Preprints. https://doi.org/10.20944/preprints202408.1782.v1
Abstract
Pandemic human influenza detections are dependent on complex, time-consuming DNA molecular amplifications that require sophisticated PCR electrophoresis, cell culture amplification and complex spectrophotometric absorption techniques. In this study, simplified rapid electrochemical sensing methods were sought via a remote cyclic voltammetry and stripping amplifier circuit using our workstation systems. A sensing probe was prepared using human DNA and a Covid 19 antigen immobilized antibody sensing amplifier with rapid accumulation time of 30 sec. Optimal experimentation was performed using a telematics WiFi wearable circuit equipped with a bioelectrochemical analyzer-2 amplifier three electrode system. Diagnostic accumulation voltammetry and cyclic redox scanning were attempted at -2.0V~2.0V potential windows and 0.2V/Sec scan rate. Anodic and cathodic real time assay was performed using saliva swab from female patients that tested negative and positive. Diagnostic results are expected to be useful for non-contact analysis and for rapid personal testing anytime, anywhere
Keywords
in vivo; influenza virus; antibody sensing; DNA immobilization,; synthetic tattoo skin probe; WiFi telemetry; Electrochemical Electrode
Subject
Chemistry and Materials Science, Analytical Chemistry
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
