Version 1
: Received: 26 August 2024 / Approved: 28 August 2024 / Online: 28 August 2024 (10:46:33 CEST)
How to cite:
Šorak, M. P.; Nikolov, A. B.; Sazdanovic, P. S.; Arsenijevic, N. S.; Milicic, V. M.; Cekovic, J. M.; Parandilovic, A. Z.; Gavrilovic, A. Z. Bioelement Concentrations in Follicular Fluid and Their Im-pact on In Vitro Fertilization Outcomes. Preprints2024, 2024082042. https://doi.org/10.20944/preprints202408.2042.v1
Šorak, M. P.; Nikolov, A. B.; Sazdanovic, P. S.; Arsenijevic, N. S.; Milicic, V. M.; Cekovic, J. M.; Parandilovic, A. Z.; Gavrilovic, A. Z. Bioelement Concentrations in Follicular Fluid and Their Im-pact on In Vitro Fertilization Outcomes. Preprints 2024, 2024082042. https://doi.org/10.20944/preprints202408.2042.v1
Šorak, M. P.; Nikolov, A. B.; Sazdanovic, P. S.; Arsenijevic, N. S.; Milicic, V. M.; Cekovic, J. M.; Parandilovic, A. Z.; Gavrilovic, A. Z. Bioelement Concentrations in Follicular Fluid and Their Im-pact on In Vitro Fertilization Outcomes. Preprints2024, 2024082042. https://doi.org/10.20944/preprints202408.2042.v1
APA Style
Šorak, M. P., Nikolov, A. B., Sazdanovic, P. S., Arsenijevic, N. S., Milicic, V. M., Cekovic, J. M., Parandilovic, A. Z., & Gavrilovic, A. Z. (2024). Bioelement Concentrations in Follicular Fluid and Their Im-pact on In Vitro Fertilization Outcomes. Preprints. https://doi.org/10.20944/preprints202408.2042.v1
Chicago/Turabian Style
Šorak, M. P., Aida Zuher Parandilovic and Aleksandra Zoran Gavrilovic. 2024 "Bioelement Concentrations in Follicular Fluid and Their Im-pact on In Vitro Fertilization Outcomes" Preprints. https://doi.org/10.20944/preprints202408.2042.v1
Abstract
Introduction: The balance of bioelements is crucial as it ensures the organism's homeostasis and proper execution of reactions within the body, nerve conductivity, and correct polarity of cell membranes, but it is also very important for fertility. It is known that disturbances in the balance of bioelements lead to reproductive dysfunction. In women, changes in the composition of follicular fluid can occur, which can lead to limited follicular growth and lack of oocyte activation. Objective: The main objective was to examine whether the concentration of bioelements Na, K, Ca, Mg, and Fe in follicular fluid influences the outcome of the in vitro fertilization process. Methods: The study involved 120 female patients undergoing in vitro fertilization. Follicular fluid obtained after follicle aspiration in the ovaries was used as biological material for analysis. The values of Na (selective electrode method), K (selective electrode method), Ca (arenajo method), Mg (spectrophotometric method), and Fe (colorimetric method) in follicular fluid were determined using the AU 680 apparatus, Beckman Coulter. Istanbul Consensus criteria for clinical embryologists were used to assess embryo quality. Statistical analysis was performed using the SPSS 20 software package. Results: Analysis of follicular fluid samples showed no correlation between the concentration of bioelements in follicular fluid and the quality of oocytes or the outcome of in vitro fertilization. Conclusion: Based on our results, it can be concluded that the concentration of bioelements in follicular fluid does not affect the outcome of in vitro fertilization.
Keywords
IVF; follicular fluid; oocytes; bioelements
Subject
Medicine and Pharmacology, Reproductive Medicine
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
