Preprint Article Version 1 This version is not peer-reviewed

Age-Related Changes in Oral Health, Salivary Parameters, Halitosis, and Systemic Diseases and Medication Usage

Version 1 : Received: 28 August 2024 / Approved: 28 August 2024 / Online: 28 August 2024 (16:36:54 CEST)

How to cite: Seo, S.; Kim, T.-S.; Lee, Y.-H. Age-Related Changes in Oral Health, Salivary Parameters, Halitosis, and Systemic Diseases and Medication Usage. Preprints 2024, 2024082091. https://doi.org/10.20944/preprints202408.2091.v1 Seo, S.; Kim, T.-S.; Lee, Y.-H. Age-Related Changes in Oral Health, Salivary Parameters, Halitosis, and Systemic Diseases and Medication Usage. Preprints 2024, 2024082091. https://doi.org/10.20944/preprints202408.2091.v1

Abstract

Background The increasing number of elderly individuals in South Korea, now entering a super-aging era, underscores the growing importance of understanding their specific oral health needs. This study investigated changes in oral health conditions, salivary parameters, halitosis, systemic diseases, and medication usage with aging. Methods This study was retrospectively conducted using the medical records of patients who presented with complaints of xerostomia or halitosis between August 2020 and May 2023. A total of 274 patients (66 males, 208 females, mean age 59.39 ± 16.10 years) were included in this study. Results Aging was found to be significantly associated with the presence of sticky saliva, poor oral hygiene, tongue coating, and halitosis (all p < 0.05). Correlation analyses further revealed significant associations between aging and several conditions, including hypertension (r = 0.495, p < 0.001), diabetes mellitus (r = 0.255, p < 0.001), amlodipine usage (r = 0.249, p = 0.001), osteoporosis (r = 0.195, p = 0.001), cardiovascular disease (r = 0.150, p = 0.013), and the presence of tongue coating (r = 0.205, p = 0.001). Conversely, none of the salivary parameters demonstrated a significant relationship with aging. Furthermore, halitosis did not exhibit significant differences across age groups (all p > 0.05), with the exception of methyl mercaptan levels, which were notably higher among patients in their 20s (p = 0.049). Conclusions The findings of this study can help clinicians develop targeted strategies to address specific oral health challenges associated with aging in elderly patients.

Keywords

aging; oral health; saliva; halitosis; systemic disease; systemic medication

Subject

Medicine and Pharmacology, Clinical Medicine

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