Version 1
: Received: 30 August 2024 / Approved: 1 September 2024 / Online: 2 September 2024 (11:33:58 CEST)
How to cite:
Vörös-Horváth, B.; Salem, A.; Kovács, B.; Széchenyi*, A.; Pál, S. Systematic Study of Reaction Conditions for Size Controlled Synthesis of Silica Nanoparticles. Preprints2024, 2024090025. https://doi.org/10.20944/preprints202409.0025.v1
Vörös-Horváth, B.; Salem, A.; Kovács, B.; Széchenyi*, A.; Pál, S. Systematic Study of Reaction Conditions for Size Controlled Synthesis of Silica Nanoparticles. Preprints 2024, 2024090025. https://doi.org/10.20944/preprints202409.0025.v1
Vörös-Horváth, B.; Salem, A.; Kovács, B.; Széchenyi*, A.; Pál, S. Systematic Study of Reaction Conditions for Size Controlled Synthesis of Silica Nanoparticles. Preprints2024, 2024090025. https://doi.org/10.20944/preprints202409.0025.v1
APA Style
Vörös-Horváth, B., Salem, A., Kovács, B., Széchenyi*, A., & Pál, S. (2024). Systematic Study of Reaction Conditions for Size Controlled Synthesis of Silica Nanoparticles. Preprints. https://doi.org/10.20944/preprints202409.0025.v1
Chicago/Turabian Style
Vörös-Horváth, B., Aleksandar Széchenyi* and Szilárd Pál. 2024 "Systematic Study of Reaction Conditions for Size Controlled Synthesis of Silica Nanoparticles" Preprints. https://doi.org/10.20944/preprints202409.0025.v1
Abstract
This study presents a reproducible and scalable method for synthesizing silica nanoparticles (SNPs) with controlled sizes below 200 nm, achieved by systematically varying three key reaction parameters: ammonium hydroxide concentration, water concentration, and temperature. SNPs with high monodispersity and controlled dimensions were produced by optimizing these factors. The results indicated a direct correlation between ammonium hydroxide concentration and particle size, while higher temperatures resulted in smaller particles with increased polydispersity. Water concentration also influenced particle size, with a quadratic relationship observed. This method provides a robust approach for tailoring SNP sizes, with significant implications for biomedical applications, particularly in drug delivery and diagnostics. Using eco-friendly solvents such as ethanol further enhances the sustainability and cost-effectiveness of the process.
Keywords
Silica nanoparticles; Nanoparticle synthesis; Particle size control; Stöber method; Ammonium hydroxide concentration; Water concentration; Temperature effect
Subject
Chemistry and Materials Science, Nanotechnology
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
