PreprintCase ReportVersion 1This version is not peer-reviewed
Arthroscopic Debridement Enhanced by Intra-articular Antibiotic-Loaded Calcium Sulphate Beads for Septic Arthritis of a Native Knee Following Iatrogenic Joint Injection: A Case Report
Version 1
: Received: 3 September 2024 / Approved: 3 September 2024 / Online: 3 September 2024 (14:35:52 CEST)
How to cite:
Alongi, S.; Troiano, E.; Latino, C.; Colasanti, G. B.; Greco, T.; Perisano, C.; Mosca, M.; Giannotti, S.; Mondanelli, N. Arthroscopic Debridement Enhanced by Intra-articular Antibiotic-Loaded Calcium Sulphate Beads for Septic Arthritis of a Native Knee Following Iatrogenic Joint Injection: A Case Report. Preprints2024, 2024090238. https://doi.org/10.20944/preprints202409.0238.v1
Alongi, S.; Troiano, E.; Latino, C.; Colasanti, G. B.; Greco, T.; Perisano, C.; Mosca, M.; Giannotti, S.; Mondanelli, N. Arthroscopic Debridement Enhanced by Intra-articular Antibiotic-Loaded Calcium Sulphate Beads for Septic Arthritis of a Native Knee Following Iatrogenic Joint Injection: A Case Report. Preprints 2024, 2024090238. https://doi.org/10.20944/preprints202409.0238.v1
Alongi, S.; Troiano, E.; Latino, C.; Colasanti, G. B.; Greco, T.; Perisano, C.; Mosca, M.; Giannotti, S.; Mondanelli, N. Arthroscopic Debridement Enhanced by Intra-articular Antibiotic-Loaded Calcium Sulphate Beads for Septic Arthritis of a Native Knee Following Iatrogenic Joint Injection: A Case Report. Preprints2024, 2024090238. https://doi.org/10.20944/preprints202409.0238.v1
APA Style
Alongi, S., Troiano, E., Latino, C., Colasanti, G. B., Greco, T., Perisano, C., Mosca, M., Giannotti, S., & Mondanelli, N. (2024). Arthroscopic Debridement Enhanced by Intra-articular Antibiotic-Loaded Calcium Sulphate Beads for Septic Arthritis of a Native Knee Following Iatrogenic Joint Injection: A Case Report. Preprints. https://doi.org/10.20944/preprints202409.0238.v1
Chicago/Turabian Style
Alongi, S., Stefano Giannotti and Nicola Mondanelli. 2024 "Arthroscopic Debridement Enhanced by Intra-articular Antibiotic-Loaded Calcium Sulphate Beads for Septic Arthritis of a Native Knee Following Iatrogenic Joint Injection: A Case Report" Preprints. https://doi.org/10.20944/preprints202409.0238.v1
Abstract
Septic arthritis (SA) represents an orthopedics urgency and mainly affects the knee joint. Due to its devastating effects on cartilage, immediate management is crucial. SA is characterized by an an-nual incidence of 2 to 10 cases per 100,000 individuals, with mortality rates fluctuating between 0.5% and 15%, with a substantially higher mortality rate observed in older people (15%) in con-trast to younger cohorts (4%). The etiology of septic arthritis is multifactorial: a spectrum of Gram-positive and Gram-negative bacteria can contribute to the development of this condition, especially Staphylococcus aureus. The treatment involves urgent (arthroscopic or arthrotomic) debridement associated with adequate antibiotic therapy. Intra-articular antibiotic carriers can also be used to increase their local concentration and effectiveness. The case of a 67-years-old woman affected by knee SA from methicillin-susceptible S. aureus is presented. She was treated with an arthroscopic debridement enhanced by intra-articular antibiotic-loaded calcium sulphate beads, together with antibiotic therapy. At 2-year follow-up, the infection has been eradicated and the patient fully recovered. This is the first description, to our knowledge, in English Literature of the use of antibiotic-loaded calcium sulphate beads as an adjuvant in the surgical treatment of SA of a native knee joint.
Medicine and Pharmacology, Orthopedics and Sports Medicine
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
