Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

The Impact of Breast Cancer Risk Factors: Socio-Economic, Hormonal, and Clinical Insights from Hassan II Regional Oncology Center, Morocco

Version 1 : Received: 10 September 2024 / Approved: 10 September 2024 / Online: 11 September 2024 (00:14:10 CEST)

How to cite: Fatima Ezahra, M.; Latifa, D.; Boutaina, A.; Mohammed, A.; El Mzibri, M.; Laïla, B.; Ghizlane, R.; Taoufiq, F. The Impact of Breast Cancer Risk Factors: Socio-Economic, Hormonal, and Clinical Insights from Hassan II Regional Oncology Center, Morocco. Preprints 2024, 2024090823. https://doi.org/10.20944/preprints202409.0823.v1 Fatima Ezahra, M.; Latifa, D.; Boutaina, A.; Mohammed, A.; El Mzibri, M.; Laïla, B.; Ghizlane, R.; Taoufiq, F. The Impact of Breast Cancer Risk Factors: Socio-Economic, Hormonal, and Clinical Insights from Hassan II Regional Oncology Center, Morocco. Preprints 2024, 2024090823. https://doi.org/10.20944/preprints202409.0823.v1

Abstract

Background/Objectives: This study aimed to identify various risk factors associated with breast cancer and explore different treatment strategies based on socio-economic, hormonal, and clinical perspectives.; Methods: We analyzed socio-economic, hormonal, genetic, and clinical variables using data from 356 questionnaires obtained from breast cancer patients at Hassan II Regional Hospital in Agadir, Morocco ; Results:The study reveals that the average age of breast cancer patients is 50 ± 10.72 years, with a mode of 47 years and an age range from 29 to 94 years. Notably, women aged 38 are most frequently diagnosed with triple-negative breast cancer. Significant socio-economic trends were observed among the participants, with the majority being housewives (91%) and nearly half residing in rural areas (48.60%). High rates of illiteracy (74.72%) and financial difficulties (54.2%) pose challenges in accessing healthcare services. Psychological distress is prevalent, with 40.7% experiencing anxiety and 30.1% experiencing sadness. The use of oral contraceptives varies, with implications for breast cancer risk. Additionally, statistics on menarche and menopause suggest hormonal influences on breast cancer development. Histological analysis indicates a predominance of grade II invasive ductal carcinoma and left breast localization. Metastases are present in nearly 38.20% of cases. Notably, surgery as the primary treatment effectively treats medium-sized tumors while limiting metastasis. Furthermore, a comparison of treatment strategies reveals a preference for letrozole among postmenopausal patients and tamoxifen among premenopausal patients; Conclusions:These findings highlight the complexity of breast cancer risk factors and therapeutic approaches, emphasizing the importance of personalized care and targeted interventions.

Keywords

Breast cancer; socio-economic; factors; hormonal; clinical; treatments; stategies

Subject

Medicine and Pharmacology, Other

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