The Economic Impact of Post-Traumatic Stress Disorder Among Patients with Systemic Autoimmune Diseases During the COVID-19 Pandemic

Valentina Lorenzoni; Gianni Andreozzi; Ilaria Palla; Chiara Tani; Claudia Carmassi; Giovanni Fulvio; Francesca Trentin; Sara Fantasia; Lorenzo Conti; Liliana Dell'Osso; Marta Mosca; Giuseppe Turchetti

doi:10.20944/preprints202409.1324.v1

Preprint Article Version 1 This version is not peer-reviewed

Version 1 : Received: 17 September 2024 / Approved: 17 September 2024 / Online: 17 September 2024 (12:51:34 CEST)

Background: The present work aimed to estimate the economic impact of PTSD following COVID-19 in a population of patients affected by systemic autoimmune disease (SAD) using a cost-of-illness approach and accounting for the perspective of society. Methods: Considering data collected from SAD patients enrolled in a specialized outpatient clinic in the Tuscany region, Italy, generalized-linear-models and LASSO logistic regression were used to evaluate the impact of PTSD on costs and its relevance as possible predictors of being a high-cost patient, respectively. Results: Considering 301 SAD patients, 161 (51.2%) of whom diagnosed with PTSD, the overall costs were 3,670 [890;40,529] Euro per patient/year among patients with PTSD and 2,736.7 [283;21,078] Euro per patient/year among those without PTSD (P-value

Keywords: COVID-19; post-traumatic stress disorder; systemic autoimmune disease; economic; healthcare costs; indirect costs; LASSO regression

Public Health and Healthcare, Health Policy and Services

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The Economic Impact of Post-Traumatic Stress Disorder Among Patients with Systemic Autoimmune Diseases During the COVID-19 Pandemic

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