Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

The Effects of Kale Biofortified with 8-Hydroxy-7-Iodo-5-Quinolinesulfonic Acid on Iodine Concentration in Various Tissues and Changes of Selected Thyroid-Regulated Biochemical Parameters in Blood Serum of Wistar Rats

Joanna Krzemińska
ORCID logo ,
Ewa Piątkowska
,
Aneta Kopeć
ORCID logo ,
Sylwester Smoleń
ORCID logo ,
Teresa Leszczyńska
ORCID logo ,
Aneta Agnieszka Koronowicz
*
Version 1 : Received: 20 September 2024 / Approved: 23 September 2024 / Online: 23 September 2024 (04:42:14 CEST)

How to cite: Krzemińska, J.; Piątkowska, E.; Kopeć, A.; Smoleń, S.; Leszczyńska, T.; Koronowicz, A. A. The Effects of Kale Biofortified with 8-Hydroxy-7-Iodo-5-Quinolinesulfonic Acid on Iodine Concentration in Various Tissues and Changes of Selected Thyroid-Regulated Biochemical Parameters in Blood Serum of Wistar Rats. Preprints 2024, 2024091691. https://doi.org/10.20944/preprints202409.1691.v1 Krzemińska, J.; Piątkowska, E.; Kopeć, A.; Smoleń, S.; Leszczyńska, T.; Koronowicz, A. A. The Effects of Kale Biofortified with 8-Hydroxy-7-Iodo-5-Quinolinesulfonic Acid on Iodine Concentration in Various Tissues and Changes of Selected Thyroid-Regulated Biochemical Parameters in Blood Serum of Wistar Rats. Preprints 2024, 2024091691. https://doi.org/10.20944/preprints202409.1691.v1

Abstract

Dietary intake of Wistar rats of biofortified with 8-hydroxy-7-iodo-5-quinolinesulfonic acid (8-OH-7-I-5QSA) kale of both cultivars ‘Oldenbor F1’ and ‘Redbor F1’ for 8 weeks resulted in sig-nificantly higher iodine concentrations in the urine and kidneys of rats, which proves iodine bio-availability. Rats diets with 'Oldenbor F1' and 'Redbor F1' kale non- and -biofortified with 8-OH-7-I-5QSA had a significantly lower or a tendency for lower concentration of TSH, triglyc-eride, total and direct bilirubin, TBARs, uric acid, aspartate aminotransferase (AST) and alanine aminotransferase (ALT) concentrations in serum. Dietary intake of 'Oldenbor F1' and 'Redbor F1' kale biofortified with 8-OH-7-I-5QSA significantly increased the total antioxidant status (TAS). The study confirms that kale biofortified with iodine in organic form iodoquinoline 8-OH-7-I-5QSA is bioavailable and well absorbed by the Wistar rat and has a positive effect on selected biochemical parameters.

Keywords

iodoquinoline; 8-hydroxy-7-iodo-5-quinolinesulfonic acid; iodine; kale; biofortification; biochemical parameters; iodine bioavailability  

Subject

Biology and Life Sciences, Food Science and Technology

Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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