Preprint Article Version 1 This version is not peer-reviewed

Evaluation of an Alternative Screening Method for Gestational Diabetes Diagnosis During the COVID-19 Pandemic (DIABECOVID STUDY): An Observational Cohort Study

Version 1 : Received: 24 September 2024 / Approved: 25 September 2024 / Online: 25 September 2024 (12:18:23 CEST)

How to cite: Casellas, A.; Martinez, C.; Amigó, J.; Ferrer, R.; Marti, L.; Merced, C.; Medina, M. C.; Molinero, I.; Calveiro, M.; Maroto, A.; del Barco, E.; Carreras, E.; Goya, M. M. Evaluation of an Alternative Screening Method for Gestational Diabetes Diagnosis During the COVID-19 Pandemic (DIABECOVID STUDY): An Observational Cohort Study. Preprints 2024, 2024091985. https://doi.org/10.20944/preprints202409.1985.v1 Casellas, A.; Martinez, C.; Amigó, J.; Ferrer, R.; Marti, L.; Merced, C.; Medina, M. C.; Molinero, I.; Calveiro, M.; Maroto, A.; del Barco, E.; Carreras, E.; Goya, M. M. Evaluation of an Alternative Screening Method for Gestational Diabetes Diagnosis During the COVID-19 Pandemic (DIABECOVID STUDY): An Observational Cohort Study. Preprints 2024, 2024091985. https://doi.org/10.20944/preprints202409.1985.v1

Abstract

Aim: To evaluate the impact of applying alternative diagnostic criteria for gestational diabetes mellitus (GDM) during the COVID-19 pandemic on GDM prevalence, obstetrical and perinatal outcomes, and costs, as compared to the standard diagnostic method. Methods: A cohort of pregnant individuals undergoing GMD screening with the alternative GDM method, which uses plasma glucose (fasting or non-fasting) and HbA1c, was compared with a cohort of pregnant individuals undergoing the standard GDM screening method. Both cohorts were obtained from 6 hospitals across Catalonia, Spain, from April 2020 to April 2022. The primary outcome was large for gestational age rate at birth. Secondary outcomes were composite adverse outcomes including pregnancy complications, delivery complications, and neonatal complications. Cost differences between screening methods were also evaluated. A similar analysis was performed in the subgroup diagnosed with GDM. Results: Data were collected from 1,543 pregnant individuals in the standard screening group and 2,197 in the alternative screening group. The standard screening group had a higher GDM diagnostic rate than the alternative screening group (10.8% vs 6.9%, respectively; p

Keywords

Gestational diabetes; COVID-19; O’Sullivan; OGTT; glucose level; glycated haemoglobin; screening; macrosomia; large for gestational age (LGA); neonatal hypoglycemia

Subject

Medicine and Pharmacology, Obstetrics and Gynaecology

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