The Impact of Bioactive Molecules from Probiotics on Child Health: A Comprehensive Review

Linda P. Guamán; Saskya E. Carrera-Pacheco; Johana Zúñiga-Miranda; Enrique Teran; Cesar Erazo; Carlos Barba-Ostria

doi:10.20944/preprints202410.0110.v1

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preprints.org > biology and life sciences > life sciences > doi: 10.20944/preprints202410.0110.v1

Preprint Review Version 1 This version is not peer-reviewed

The Impact of Bioactive Molecules from Probiotics on Child Health: A Comprehensive Review

Linda P. Guamán

^* ,

Saskya E. Carrera-Pacheco

Johana Zúñiga-Miranda

Enrique Teran

Cesar Erazo

Carlos Barba-Ostria

Version 1 : Received: 1 October 2024 / Approved: 2 October 2024 / Online: 2 October 2024 (10:45:10 CEST)

How to cite: Guamán, L. P.; Carrera-Pacheco, S. E.; Zúñiga-Miranda, J.; Teran, E.; Erazo, C.; Barba-Ostria, C. The Impact of Bioactive Molecules from Probiotics on Child Health: A Comprehensive Review. Preprints 2024, 2024100110. https://doi.org/10.20944/preprints202410.0110.v1 Guamán, L. P.; Carrera-Pacheco, S. E.; Zúñiga-Miranda, J.; Teran, E.; Erazo, C.; Barba-Ostria, C. The Impact of Bioactive Molecules from Probiotics on Child Health: A Comprehensive Review. Preprints 2024, 2024100110. https://doi.org/10.20944/preprints202410.0110.v1

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MDPI and ACS Style

Guamán, L. P.; Carrera-Pacheco, S. E.; Zúñiga-Miranda, J.; Teran, E.; Erazo, C.; Barba-Ostria, C. The Impact of Bioactive Molecules from Probiotics on Child Health: A Comprehensive Review. Preprints 2024, 2024100110. https://doi.org/10.20944/preprints202410.0110.v1

APA Style

Guamán, L. P., Carrera-Pacheco, S. E., Zúñiga-Miranda, J., Teran, E., Erazo, C., & Barba-Ostria, C. (2024). The Impact of Bioactive Molecules from Probiotics on Child Health: A Comprehensive Review. Preprints. https://doi.org/10.20944/preprints202410.0110.v1

Chicago/Turabian Style

Guamán, L. P., Cesar Erazo and Carlos Barba-Ostria. 2024 "The Impact of Bioactive Molecules from Probiotics on Child Health: A Comprehensive Review" Preprints. https://doi.org/10.20944/preprints202410.0110.v1

Abstract

This review investigates the impact of bioactive molecules produced by probiotics on child health, focusing on their roles in modulating gut microbiota, enhancing immune function, and supporting overall development. Key metabolites, including short-chain fatty acids (SCFAs), bacteriocins, exopolysaccharides (EPS), vitamins, and gamma-aminobutyric acid (GABA), are highlighted for their ability to maintain gut health, regulate inflammation, and support neurodevelopment. Clinical studies demonstrate that specific probiotics and their metabolites can reduce gastrointestinal disorders, enhance immune responses, and decrease the incidence of allergies and respiratory infections in pediatric populations. Additionally, postbiotics—bioactive compounds from probiotic fermentation—offer promising benefits, such as improved gut barrier function, reduced inflammation, and enhanced nutrient absorption, while presenting fewer safety concerns compared to live probiotics. By examining the mechanisms of action and clinical evidence, this review underscores the potential of integrating probiotics and postbiotics into pediatric healthcare strategies to promote optimal growth, development, and overall health in children.

Keywords

probiotics; short chain fatty acids; exopolissaccharide; vitamins; peptides; postbiotics

Subject

Biology and Life Sciences, Life Sciences

Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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