PreprintArticleVersion 1This version is not peer-reviewed
Computed Tomography-Measured Cranial Mediastinal Lymphadenomegaly Is Associated with Elevated C-Reactive Protein in Small Dogs with Non-Neoplastic Disorders
Version 1
: Received: 3 October 2024 / Approved: 3 October 2024 / Online: 4 October 2024 (09:21:18 CEST)
How to cite:
Ide, Y.; Furusawa, Y.; Sogawa, T.; Takahashi, K.; Kuramoto, T.; Noguchi, A.; Takahashi, M.; Miura, N. Computed Tomography-Measured Cranial Mediastinal Lymphadenomegaly Is Associated with Elevated C-Reactive Protein in Small Dogs with Non-Neoplastic Disorders. Preprints2024, 2024100284. https://doi.org/10.20944/preprints202410.0284.v1
Ide, Y.; Furusawa, Y.; Sogawa, T.; Takahashi, K.; Kuramoto, T.; Noguchi, A.; Takahashi, M.; Miura, N. Computed Tomography-Measured Cranial Mediastinal Lymphadenomegaly Is Associated with Elevated C-Reactive Protein in Small Dogs with Non-Neoplastic Disorders. Preprints 2024, 2024100284. https://doi.org/10.20944/preprints202410.0284.v1
Ide, Y.; Furusawa, Y.; Sogawa, T.; Takahashi, K.; Kuramoto, T.; Noguchi, A.; Takahashi, M.; Miura, N. Computed Tomography-Measured Cranial Mediastinal Lymphadenomegaly Is Associated with Elevated C-Reactive Protein in Small Dogs with Non-Neoplastic Disorders. Preprints2024, 2024100284. https://doi.org/10.20944/preprints202410.0284.v1
APA Style
Ide, Y., Furusawa, Y., Sogawa, T., Takahashi, K., Kuramoto, T., Noguchi, A., Takahashi, M., & Miura, N. (2024). Computed Tomography-Measured Cranial Mediastinal Lymphadenomegaly Is Associated with Elevated C-Reactive Protein in Small Dogs with Non-Neoplastic Disorders. Preprints. https://doi.org/10.20944/preprints202410.0284.v1
Chicago/Turabian Style
Ide, Y., Masashi Takahashi and Naoki Miura. 2024 "Computed Tomography-Measured Cranial Mediastinal Lymphadenomegaly Is Associated with Elevated C-Reactive Protein in Small Dogs with Non-Neoplastic Disorders" Preprints. https://doi.org/10.20944/preprints202410.0284.v1
Abstract
Lymphadenomegaly is well described in dogs with neoplastic diseases, but it can also reflect in-flammation. However, its role in assessments of inflammation is little reported in the veterinary literature. Lymph nodes are most easily assessed superficially through palpation, but computed tomography (CT) enables evaluation of deep lymph nodes. Accordingly, we investigated associ-ations between maximal lymph node diameter and plasma concentrations of C-reactive protein (CRP), a sensitive inflammatory marker, targeting three deep lymph nodes (sternal, cranial me-diastinal, and internal iliac). We evaluated data from small dogs with non-neoplastic diseases that underwent synchronous CT and blood biochemistry at our institution. We found that cranial mediastinal lymph node diameter was significantly greater in dogs with clinically elevated CRP than those with clinically unremarkable CRP (CRP 0.7-7.0< mg/dL vs.
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
