Ganaha, A.; Nojiri, N.; Nakamura, T.; Higa, T.; Kondo, S.; Tono, T. Diagnosis of Enlarged Vestibular Aqueduct using Wideband Tympanometry. Preprints2024, 2024100576. https://doi.org/10.20944/preprints202410.0576.v1
APA Style
Ganaha, A., Nojiri, N., Nakamura, T., Higa, T., Kondo, S., & Tono, T. (2024). Diagnosis of Enlarged Vestibular Aqueduct using Wideband Tympanometry. Preprints. https://doi.org/10.20944/preprints202410.0576.v1
Chicago/Turabian Style
Ganaha, A., Shunsuke Kondo and Tetsuya Tono. 2024 "Diagnosis of Enlarged Vestibular Aqueduct using Wideband Tympanometry" Preprints. https://doi.org/10.20944/preprints202410.0576.v1
Abstract
Background: Wideband tympanometry (WBT) has the potential to distinguish various mechanical middle ear and inner ear pathologies noninvasively. This study investigated the diagnostic value of WBT in the diagnosis of enlarged vestibular aqueduct (EVA). Methods: The absorbance and resonance frequency (RF) of patients with EVA (40 ears, 25 patients) and matched population controls (39 ears, 28 subjects) were compared, alongside receiver operating characteristic (ROC) analysis. Correlations between VA width and RF were also examined. Results: Patients with EVA had higher absorbance at low frequencies (226–917 Hz) and lower absorbance at high frequencies (2,520–4,896 Hz) compared to controls. The RF of the EVA group was significantly lower versus controls (751 [391–1,165] vs. 933 [628–1,346] Hz). ROC analysis revealed area under the curve values of 0.771 and 0.801 respectively, for absorbance and RF. RF had a sensitivity, specificity, positive predictive value, and negative predictive value of 74.4%, 82.5%, 76.7%, and 80.6%, respectively, for diagnosing EVA. In the EVA group, the VA midpoint width (r = −0.334) and VA petrous width (r = −0.402) both significantly correlated with RF. Conclusion: Our findings support the utility of WBT for diagnosing EVA, with RF as the optimal index used.
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
