Preprint Review Version 1 This version is not peer-reviewed

Role of Lipoprotein(a) Reduction in Cardiovascular Disease

Version 1 : Received: 8 October 2024 / Approved: 8 October 2024 / Online: 9 October 2024 (09:25:50 CEST)

How to cite: Schuth, U. H.; Gill, K.; Bawamia, B.; Telyuk, P.; Austin, D.; Zaman, A. G. Role of Lipoprotein(a) Reduction in Cardiovascular Disease. Preprints 2024, 2024100673. https://doi.org/10.20944/preprints202410.0673.v1 Schuth, U. H.; Gill, K.; Bawamia, B.; Telyuk, P.; Austin, D.; Zaman, A. G. Role of Lipoprotein(a) Reduction in Cardiovascular Disease. Preprints 2024, 2024100673. https://doi.org/10.20944/preprints202410.0673.v1

Abstract

Recent studies have shown that Lipoprotein(a) (Lp(a)) is an important risk factor for a plethora of different cardiovascular diseases. It has been proven that Lp(a) levels are genetically determined, and correlate with risk of cardiovascular disease, independent of lifestyle factors. As of yet, treatment options to reduce Lp(a) levels are limited, but new research into Lp(a) reduction yields promising results. This review delves into Lp(a) biochemistry, mechanism of effect, association between Lp(a) and cardiovascular diseases, and possible therapies to minimize cardiovascular disease.

Keywords

Lipoprotein(a); cardiovascular disease; atherosclerosis

Subject

Biology and Life Sciences, Life Sciences

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