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Preprint
Article
Viral Markers Inside Neoplastic Tissues in a Set of 68 Samples from 57 Upper Airways Cancer Cases
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This version is not peer-reviewed
Abstract
A contribution of Epstein-Barr Virus (EBV), Human Cytomegalovirus (HCMV), and certain types of Human Papilloma Virus (HPV) to the overall pathogenesis of upper airways cancers seems a priori reasonably conceivable. The existing evidence mostly relates them to nasopharyngeal squamous and undifferentiated carcinomas; indications emerge about their involvement in other upper airways cancers too. Markers of EBV, HCMV, HPV16, HPV18, (and Mycoplasma pneumoniae as a negative control) were searched in a series of 68 samples of neoplastic tissues from 57 patients diagnosed with different upper airways cancers. The results provide clues in favor of an actual role of EBV, HCMV, and HPV18, in the web of causation of upper airways squamous and undifferentiated carcinomas, possibly of upper airways adenocarcinomas too.
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Subject: Public Health and Healthcare - Public, Environmental and Occupational Health
Copyright: This open access article is published under a Creative Commons CC BY 4.0 license, which permit the free download, distribution, and reuse, provided that the author and preprint are cited in any reuse.
Submitted:
14 October 2024
Posted:
16 October 2024
You are already at the latest version
Alerts
This version is not peer-reviewed
Submitted:
14 October 2024
Posted:
16 October 2024
You are already at the latest version
Alerts
Abstract
A contribution of Epstein-Barr Virus (EBV), Human Cytomegalovirus (HCMV), and certain types of Human Papilloma Virus (HPV) to the overall pathogenesis of upper airways cancers seems a priori reasonably conceivable. The existing evidence mostly relates them to nasopharyngeal squamous and undifferentiated carcinomas; indications emerge about their involvement in other upper airways cancers too. Markers of EBV, HCMV, HPV16, HPV18, (and Mycoplasma pneumoniae as a negative control) were searched in a series of 68 samples of neoplastic tissues from 57 patients diagnosed with different upper airways cancers. The results provide clues in favor of an actual role of EBV, HCMV, and HPV18, in the web of causation of upper airways squamous and undifferentiated carcinomas, possibly of upper airways adenocarcinomas too.
Keywords:
Subject: Public Health and Healthcare - Public, Environmental and Occupational Health
Copyright: This open access article is published under a Creative Commons CC BY 4.0 license, which permit the free download, distribution, and reuse, provided that the author and preprint are cited in any reuse.
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