PreprintArticleVersion 1This version is not peer-reviewed
Nutritional, Metabolic and Inflammatory Alterations in Children with Chylous Effusion in the Postoperative Period of Cardiac Surgery: A Descriptive Cohort
Version 1
: Received: 17 October 2024 / Approved: 18 October 2024 / Online: 18 October 2024 (14:21:33 CEST)
How to cite:
da Silva, S. V.; Hortencio, T. D.; Teles, L. O.; Esteves, A. L.; José Negrão Nogueira, R. Nutritional, Metabolic and Inflammatory Alterations in Children with Chylous Effusion in the Postoperative Period of Cardiac Surgery: A Descriptive Cohort. Preprints2024, 2024101477. https://doi.org/10.20944/preprints202410.1477.v1
da Silva, S. V.; Hortencio, T. D.; Teles, L. O.; Esteves, A. L.; José Negrão Nogueira, R. Nutritional, Metabolic and Inflammatory Alterations in Children with Chylous Effusion in the Postoperative Period of Cardiac Surgery: A Descriptive Cohort. Preprints 2024, 2024101477. https://doi.org/10.20944/preprints202410.1477.v1
da Silva, S. V.; Hortencio, T. D.; Teles, L. O.; Esteves, A. L.; José Negrão Nogueira, R. Nutritional, Metabolic and Inflammatory Alterations in Children with Chylous Effusion in the Postoperative Period of Cardiac Surgery: A Descriptive Cohort. Preprints2024, 2024101477. https://doi.org/10.20944/preprints202410.1477.v1
APA Style
da Silva, S. V., Hortencio, T. D., Teles, L. O., Esteves, A. L., & José Negrão Nogueira, R. (2024). Nutritional, Metabolic and Inflammatory Alterations in Children with Chylous Effusion in the Postoperative Period of Cardiac Surgery: A Descriptive Cohort. Preprints. https://doi.org/10.20944/preprints202410.1477.v1
Chicago/Turabian Style
da Silva, S. V., Alexandre Lima Esteves and Roberto José Negrão Nogueira. 2024 "Nutritional, Metabolic and Inflammatory Alterations in Children with Chylous Effusion in the Postoperative Period of Cardiac Surgery: A Descriptive Cohort" Preprints. https://doi.org/10.20944/preprints202410.1477.v1
Abstract
Objective: The occurrence of chylous effusion in children undergoing cardiac surgery is progressively increasing due to technical advances that have led to a rise in the number of surgeries. In this context, the objective was to describe the clinical profile of a cohort of patients at the time of chylous effusion diagnosis.
Methods: A retrospective cohort analysis was conducted between January 2011 and July 2023, involving patients aged zero to 18 years, treated at a Quaternary University Hospital in southeastern Brazil. Data were obtained from the follow-up records of the Multidisciplinary Nutritional Therapy Team (MNTT) for patients who received nutritional support after developing chylous effusion in the postoperative period of cardiac surgery.
Results: The younger population predominated (median age of 6 months), with a high prevalence of malnutrition (60.9%). At the time of chylous effusion diagnosis, 83% had lymphopenia, and 74% had hypoalbuminemia. The longer the time elapsed after surgery for the onset of chylous effusion, the lower the HDL cholesterol, the lower the albumin levels, the greater the surgical complexity, and the younger and lower weight the patient. Hypocalcemia occurred in nearly half of the sample, and hypophosphatemia in 26% of the analyzed cases.
Conclusions: There was a notable presence of lymphopenia, hypoalbuminemia, and low HDL cholesterol, as well as a high incidence of mineral imbalances, particularly hypocalcemia and hypophosphatemia, which, if untreated, may lead to unfavorable outcomes. Therefore, clinical and laboratory monitoring of children in the postoperative period of cardiac surgery is important and can aid in the early diagnosis of chylous effusion and, consequently, in the timely initiation of treatment.
Keywords
Chylous effusion; cardiac surgery; chylothorax; children
Subject
Medicine and Pharmacology, Pediatrics, Perinatology and Child Health
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
