PreprintArticleVersion 1This version is not peer-reviewed
Beneficial Effect of a Nutraceutical, Containing Red Yeast Rice and Polycosanols, on Lipid Profile in Children with Moderate and Severe Hypercholesterolemia
Version 1
: Received: 28 October 2024 / Approved: 28 October 2024 / Online: 30 October 2024 (07:54:48 CET)
How to cite:
Garoufi, A.; Papadaki, M.; Kalogiannis, M.; Zerva, U.; Charakida, M.; Marmarinos, A.; Attilakos, A. Beneficial Effect of a Nutraceutical, Containing Red Yeast Rice and Polycosanols, on Lipid Profile in Children with Moderate and Severe Hypercholesterolemia. Preprints2024, 2024102241. https://doi.org/10.20944/preprints202410.2241.v1
Garoufi, A.; Papadaki, M.; Kalogiannis, M.; Zerva, U.; Charakida, M.; Marmarinos, A.; Attilakos, A. Beneficial Effect of a Nutraceutical, Containing Red Yeast Rice and Polycosanols, on Lipid Profile in Children with Moderate and Severe Hypercholesterolemia. Preprints 2024, 2024102241. https://doi.org/10.20944/preprints202410.2241.v1
Garoufi, A.; Papadaki, M.; Kalogiannis, M.; Zerva, U.; Charakida, M.; Marmarinos, A.; Attilakos, A. Beneficial Effect of a Nutraceutical, Containing Red Yeast Rice and Polycosanols, on Lipid Profile in Children with Moderate and Severe Hypercholesterolemia. Preprints2024, 2024102241. https://doi.org/10.20944/preprints202410.2241.v1
APA Style
Garoufi, A., Papadaki, M., Kalogiannis, M., Zerva, U., Charakida, M., Marmarinos, A., & Attilakos, A. (2024). Beneficial Effect of a Nutraceutical, Containing Red Yeast Rice and Polycosanols, on Lipid Profile in Children with Moderate and Severe Hypercholesterolemia. Preprints. https://doi.org/10.20944/preprints202410.2241.v1
Chicago/Turabian Style
Garoufi, A., Antonios Marmarinos and Achilleas Attilakos. 2024 "Beneficial Effect of a Nutraceutical, Containing Red Yeast Rice and Polycosanols, on Lipid Profile in Children with Moderate and Severe Hypercholesterolemia" Preprints. https://doi.org/10.20944/preprints202410.2241.v1
Abstract
The aim of the present study was to evaluate the efficacy and safety of the long-term use of a dietary supplement containing red yeast rice (RYR), combined with other natural compounds, in children and adolescents with primary hypercholesterolemia. A nutraceutical, containing RYR, polycosanols, coenzyme Q10, astaxanthin and folic acid (commercial name: Armolipid), was administered once-daily in 84 children/adolescents with moderate or severe primary hypercholesterolemia. Moreover, 19 of the participants consumed 1.5-2.5g of phytosterols daily until the initiation of dietary supplementation with Armolipid. Clinical and laboratory evaluation took place before and 6 and 16 months after treatment. Nutraceutical consumption resulted in a significant decrease in total cholesterol, low density lipoprotein - cholesterol, non-high density lipoprotein – cholesterol and apolipoprotein B levels, that remained at the long-term administration (p
Keywords
dyslipidemia; lipid profile; nutraceuticals; red yeast rice; phytosterols
Subject
Medicine and Pharmacology, Cardiac and Cardiovascular Systems
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
