Preprint Article Version 1 This version is not peer-reviewed

Visualizing Treatment Pathways Leading to Amputation and Non Amputation Using Sankey Diagrams, Sunburst Plots, and Icicle Plots in Peripheral Artery Disease [PAD] patients

Version 1 : Received: 28 October 2024 / Approved: 29 October 2024 / Online: 29 October 2024 (12:38:20 CET)

How to cite: Korutla, R.; Tedder, D.; Brogan, K.; Milosevic, M.; Cavanaugh, R.; Shehadeh, N.; Shara, N.; Lary, C.; Correll, M.; Ross, E. G.; Amal, S. Visualizing Treatment Pathways Leading to Amputation and Non Amputation Using Sankey Diagrams, Sunburst Plots, and Icicle Plots in Peripheral Artery Disease [PAD] patients. Preprints 2024, 2024102306. https://doi.org/10.20944/preprints202410.2306.v1 Korutla, R.; Tedder, D.; Brogan, K.; Milosevic, M.; Cavanaugh, R.; Shehadeh, N.; Shara, N.; Lary, C.; Correll, M.; Ross, E. G.; Amal, S. Visualizing Treatment Pathways Leading to Amputation and Non Amputation Using Sankey Diagrams, Sunburst Plots, and Icicle Plots in Peripheral Artery Disease [PAD] patients. Preprints 2024, 2024102306. https://doi.org/10.20944/preprints202410.2306.v1

Abstract

Cardiovascular surgeries, though lifesaving, can lead to complications requiring further interventions, including amputations. This study uses Sankey diagrams, Sunburst plots, and Icicle plots to analyze treatment pathways in patients with peripheral artery disease (PAD), focusing on those that lead to amputation versus those that do not. We found that non-amputation outcomes commonly involve anti-platelet and lipid-lowering medications, while amputation pathways, although less frequent, often share similar initial treatments but diverge later, suggesting areas for early intervention. These visualizations highlight patterns in patient care and emphasize the importance of tailored treatment strategies to reduce amputations, offering insights to predict likely outcomes based on treatment sequences.

Keywords

Data Visualization; Treatment Pathways; Cardiovascular surgery; Sankey diagram; Sunburst Plot; Icicle Plot; visualization of treatment sequences; Peripheral Arterial Disease (PAD)

Subject

Medicine and Pharmacology, Cardiac and Cardiovascular Systems

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