PreprintArticleVersion 1This version is not peer-reviewed
Effect of Sevoflurane Combined with Propofol Continuous Anaesthesia on Anaesthetic Outcome and Postoperative Analgesia and Recovery in Elderly Patients Undergoing Lower Limb Fracture Surgery
Zhao, L.; Hou, J.-D.; Chen, Y.-X.; Wang, Z.-G.; Wang, X.-R.; Chen, S.-H.; Li, L.-Y.; Wei, X.-N. Effect of Sevoflurane Combined with Propofol Continuous Anaesthesia on Anaesthetic Outcome and Postoperative Analgesia and Recovery in Elderly Patients Undergoing Lower Limb Fracture Surgery. Preprints2024, 2024110112. https://doi.org/10.20944/preprints202411.0112.v1
APA Style
Zhao, L., Hou, J. D., Chen, Y. X., Wang, Z. G., Wang, X. R., Chen, S. H., Li, L. Y., & Wei, X. N. (2024). Effect of Sevoflurane Combined with Propofol Continuous Anaesthesia on Anaesthetic Outcome and Postoperative Analgesia and Recovery in Elderly Patients Undergoing Lower Limb Fracture Surgery. Preprints. https://doi.org/10.20944/preprints202411.0112.v1
Chicago/Turabian Style
Zhao, L., Li-ying Li and Xiao-na Wei. 2024 "Effect of Sevoflurane Combined with Propofol Continuous Anaesthesia on Anaesthetic Outcome and Postoperative Analgesia and Recovery in Elderly Patients Undergoing Lower Limb Fracture Surgery" Preprints. https://doi.org/10.20944/preprints202411.0112.v1
Abstract
Objective: To investigate the effects of sevoflurane combined with propofol continuous anaesthesia on anaesthesia and postoperative analgesia and recovery in elderly patients undergoing lower limb fracture surgery.Methods: In this study, 344 elderly patients who underwent surgical treatment for lower limb fractures in our hospital between June 2020 and May 2022 were enrolled for prospective analysis, and the patients were equally divided into a control group and an experimental group by the random number table method, with 172 patients in each group.In the control group, continuous anaesthesia with propofol was used, while in the experimental group, continuous anaesthesia with sevoflurane and propofol was used. The anesthetic effect, postoperative analgesic effect, recovery effect and adverse reactions of the patients in the two groups were compared.Results: The excellent anesthesia rate in the experimental group was significantly higher than that in the control group (P<0.05); VAS scores at T1, T2, T3 and T4 were significantly lower in the experimental group than in the control group (P>0.05); Time to awaken, time to extubation and time to leave the anesthesia recovery room were all significantly lower in the experimental group than in the control group (P<0.05); The difference in the incidence of postoperative adverse reactions between the two groups was not statistically significant (P>0.05).Conclusion: Sevoflurane combined with propofol continuous anaesthesia is ideal for anaesthesia in elderly patients undergoing lower limb fracture surgery. This protocol is effective in suppressing postoperative pain and facilitating recovery from anaesthesia and does not increase the risk of postoperative adverse effects in patients.
Medicine and Pharmacology, Medicine and Pharmacology
Copyright:
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