PreprintArticleVersion 1This version is not peer-reviewed
Outcomes Of Treating Tuberculosis Patients With Drug-resistant Tuberculosis, Human Immu-nodeficiency Virus, And Nutritional Status: The Combined Impact Of Triple Challenges In Rural Eastern Cape
Version 1
: Received: 3 November 2024 / Approved: 4 November 2024 / Online: 5 November 2024 (10:36:09 CET)
How to cite:
Dlatu, N.; Faye, L. M.; Apalata, T. Outcomes Of Treating Tuberculosis Patients With Drug-resistant Tuberculosis, Human Immu-nodeficiency Virus, And Nutritional Status: The Combined Impact Of Triple Challenges In Rural Eastern Cape. Preprints2024, 2024110244. https://doi.org/10.20944/preprints202411.0244.v1
Dlatu, N.; Faye, L. M.; Apalata, T. Outcomes Of Treating Tuberculosis Patients With Drug-resistant Tuberculosis, Human Immu-nodeficiency Virus, And Nutritional Status: The Combined Impact Of Triple Challenges In Rural Eastern Cape. Preprints 2024, 2024110244. https://doi.org/10.20944/preprints202411.0244.v1
Dlatu, N.; Faye, L. M.; Apalata, T. Outcomes Of Treating Tuberculosis Patients With Drug-resistant Tuberculosis, Human Immu-nodeficiency Virus, And Nutritional Status: The Combined Impact Of Triple Challenges In Rural Eastern Cape. Preprints2024, 2024110244. https://doi.org/10.20944/preprints202411.0244.v1
APA Style
Dlatu, N., Faye, L. M., & Apalata, T. (2024). Outcomes Of Treating Tuberculosis Patients With Drug-resistant Tuberculosis, Human Immu-nodeficiency Virus, And Nutritional Status: The Combined Impact Of Triple Challenges In Rural Eastern Cape. Preprints. https://doi.org/10.20944/preprints202411.0244.v1
Chicago/Turabian Style
Dlatu, N., Lindiwe Modest Faye and Teke Apalata. 2024 "Outcomes Of Treating Tuberculosis Patients With Drug-resistant Tuberculosis, Human Immu-nodeficiency Virus, And Nutritional Status: The Combined Impact Of Triple Challenges In Rural Eastern Cape" Preprints. https://doi.org/10.20944/preprints202411.0244.v1
Abstract
Background: Treatment outcomes are vital measures of the success of TB treatment programs, especially in areas with limited re-sources, as tuberculosis continues to be a major public health issue. The study aimed to evaluate clinical data from TB-infected pa-tients' clinic files in rural areas of the Olivier Reginald Tambo District Municipality, Eastern Cape, South Africa, to understand the treatment outcomes of tuberculosis in patients with drug-resistant tuberculosis, human immunodeficiency virus, and nutritional status.
Methods: The study analyzed 360 patient files to investigate the treatment outcomes of patients with drug-resistant tuberculosis (DR-TB) and HIV, as well as a body mass index (BMI) indicating moderate to severe classification. The data included patient de-mographics, clinical characteristics, and social history. The study also detailed and analyzed culture conversion, time in treatment, and treatment outcomes. Additionally, BMI data were presented using a scatter plot to display the distribution of BMI across different age groups and genders to identify patterns and trends in obesity prevalence.
Results: The study demonstrated the high rates of both overweight and underweight individuals among middle-aged and elderly people, emphasizing the need for personalized nutritional interventions. It found that Type 1 (RR-TB) and Type 2 (MDR-TB) were the most common forms of DR-TB, with a higher prevalence of HIV-positive individuals in Type 1 (RR-TB). The study also showed the distribution of different BMI categories among DR-TB types and HIV statuses. Overall, it suggests limited connections between DR-TB type, BMI category, and HIV status in the research.
Conclusion: It is imperative to prioritize the management of co-morbid conditions in DR-TB patients, as these conditions signifi-cantly influence treatment outcomes. Targeted interventions are essential for patients with severe or complex co-morbidities.
Keywords
DR-TB; HIV status; BMI; RR-TB Type; TB-treatment outcomes; Overweight; Underweight; Nutritional Status
Subject
Public Health and Healthcare, Health Policy and Services
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
