Neuroendocrine tumors are tumors that can develop in any organ but show a predilection for the pancreas. These can be secreting or non-secreting tumors, they can be well differentiated or poorly differentiated, or neuroendocrine carcinomas. Surgical treatment is the only treatment with curative intent, but postoperatively it shows an increased incidence of postoperative pancreatic fistulas. We carried out a retrospective study, which included 26 patients with neuroendocrine tumors and neuroendocrine carcinomas, for whom we performed cephalic duodenopancreatectomies, distal pancreatectomies or enucleation. In our study group, the incidence of pancreatic fistula was 28%, and a series of risk factors such as the type of surgery, histological type, obesity and dynamic hemoglobin value was indicated.