The growing demand for accessible and effective e-learning platforms has led to an increased focus on innovative solutions to address the challenges posed by diverse linguistic backgrounds of learners. This paper explores the use of AI-generated virtual speakers to enhance multilingual e-learning experiences. The study employs a system developed using Google Sheets and Google Script to create and manage multilingual courses, integrating AI-powered virtual speakers to deliver content in learners' native languages. The e-learning platform used is a customized Moodle, and three courses were developed: “Mental Wellbeing in Mining”, “Rescue in the Mine” and “Risk Assessment” for a European ERASMUS+ project. The study involved 150 participants from various educational and professional backgrounds. The main findings indicate that AI-generated virtual speakers significantly improve the accessibility of e-learning content. Participants preferred content in their native language and found AI-generated videos effective and engaging. The study concludes that AI-generated virtual speakers offer a promising approach to overcoming linguistic barriers in e-learning, providing personalized and adaptive learning experiences. Future research should focus on addressing ethical considerations, such as data privacy and algorithmic bias, and expanding the user base to include more languages and proficiency levels.