Search | Preprints.org

Preprint ARTICLE | doi:10.20944/preprints202102.0359.v2

Factors Affecting Customer Satisfaction & Loyalty in Online Food Delivery Service during COVID-19 Pandemic: Its Relation with Open Innovation

Yogi Tri Prasetyo, Hans Tanto, Martinus Mariyanto, Christopher Hanjaya, Michael Nayat Young, Satria Fadil Persada, Bobby Ardiansyah Miraja, A.A.N. Perwira Redi

Subject: Engineering, Automotive Engineering Keywords: food delivery; customer satisfaction; new normal; COVID-19; theory of planned behavior

Online: 19 February 2021 (10:01:10 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202012.0463.v1

Burnout Prevalence and Its Associating Factors among Malaysian Healthcare Workers during COVID-19 Pandemic: An Embedded Mixed-Method Study

Nurhanis Syazni Roslan, Muhamad Saiful Bahri Yusoff, Asrenee Ab Razak, Karen Morgan

Subject: Medicine And Pharmacology, Immunology And Allergy Keywords: psychological wellbeing; burnout; health personnel; caregiver; pandemic

Online: 18 December 2020 (11:58:12 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202007.0639.v2

Asymmetric Conservation within Pairs of Co-occurred Motifs Mediates Weak Direct Binding of Transcription Factors in ChIP-seq Data

Victor Levitsky, Dmitry Oshchepkov, Elena Zemlyanskaya, Tatyana Merkulova

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: chromatin immunoprecipitation with massively parallel sequencing, transcription factors binding sites prediction; cooperative binding of transcription factors; composite elements; motifs conservation; classification of transcription factors; ETS transcription factor family; direct binding of transcription factors; overlap of motifs

Online: 20 August 2020 (13:43:09 CEST)

Show abstract| Download PDF| Supplementary Files| Share

Preprint REVIEW | doi:10.20944/preprints202007.0674.v1

Over-production of Therapeutic Growth Factors for Articular Cartilage Regeneration by Protein Production Platforms and Protein Packaging Cell Lines

Ali Mobasheri, Heonsik Choi, Pablo Martín-Vasallo

Subject: Biology And Life Sciences, Anatomy And Physiology Keywords: osteoarthritis; articular cartilage; degeneration; regeneration; therapeutic protein; growth factor; protein production platform; protein packaging cell line; transforming growth factor β (TGF-β); GP2-293 cells; TissueGene-C

Online: 28 July 2020 (10:16:51 CEST)

Show abstract| Download PDF| Share

This review article focuses on the current state-of-the-art in the area of cellular and molecular biotechnology for over-production of clinically relevant therapeutic and anabolic growth factors. We discuss how the currently available tools and emerging technologies can be used for the regenerative treatment of osteoarthritis (OA). Transfected protein packaging cell lines such as GP-293 cells may be used as “cellular factories” for large-scale production of therapeutic proteins and pro-anabolic growth factors, particularly in the context of cartilage regeneration. However, when irradiated with gamma or x-rays, these cells lose their capacity for replication, which actually makes them safe for use as a live cell component of intra-articular injections. This innovation is already here, in the form of TissueGene-C, a new biological drug which consists of normal allogeneic primary chondrocytes combined with transduced GP2-293 cells that overexpress the growth factor transforming growth factor β1 (TGF-β1). TissueGene-C has revolutionized the concept of cell therapy, allowing drug companies to develop live cells as biological drug delivery systems for direct intra-articular injection of growth factors whose half-lives are in the order of minutes. Therefore, in this paper, we discuss the potential for new innovations in regenerative medicine for degenerative diseases of synovial joints using mammalian protein production platforms, specifically protein packaging cell lines, for over-producing growth factors for cartilage tissue regeneration and give recent examples. Mammalian protein production platforms that incorporate protein packaging eukaryotic cell lines are superior to prokaryotic bacterial expression systems and are likely to have a significant impact on the development of new humanized biological growth factor therapies for treating focal cartilage defects and more generally for the treatment of degenerative joint diseases such as OA, especially when injected directly into the joint.

Preprint ARTICLE | doi:10.20944/preprints202006.0237.v1

Cardiovascular Risk Factors and Evolution of Patients Attended with COVID-19 in a National Reference Hospital from Lima, Peru

Germán V. Valenzuela, Alfonso J. Rodriguez-Morales, Roxana Mamani, Ricardo Ayala, Katherine Pérez, Cynthia Sarmiento, Jessica Calcino, Luis García, José Amado

Subject: Medicine And Pharmacology, Epidemiology And Infectious Diseases Keywords: COVID-19; SARS-CoV-2; risk factors; outcomes; cardiovascular; Latin America.

Online: 19 June 2020 (10:22:50 CEST)

Show abstract| Download PDF| Share

Working Paper REVIEW

Genetic Interaction Between the Non-homologous End Joining Factors during B and T Lymphocyte Development: In Vivo Mouse Models

Sergio Castañeda-Zegarra, Marion Fernandez-Berrocal, Max Tkachov, Rouan Yao, Nikki Lyn Esnardo Upfold, Valentyn Oksenych

Subject: Biology And Life Sciences, Cell And Developmental Biology Keywords: B cell; V(D)J recombination; mouse model; NHEJ; DNA repair

Online: 12 June 2020 (07:53:17 CEST)

Show abstract| Download PDF| Share

Preprint REVIEW | doi:10.20944/preprints202005.0452.v1

Optimising ‘Positive’ Findings from Judgement Bias Tests: A Consideration of Inherent Confounding Factors Associated with Test Design and Biology

Alexandra Whittaker, Timothy Barker

Subject: Social Sciences, Sociology Keywords: Judgement Bias; Personality; Social Status; Test Design

Online: 27 May 2020 (12:10:45 CEST)

Show abstract| Download PDF| Share

Preprint REVIEW | doi:10.20944/preprints202002.0451.v1

Identifying Tools That Assess Factors That May Lead to Adverse Effects in Australian Aged-Care Facilities: A Scoping Review

Haider Saddam Qasim, Maree Simpson, Yann Guisard, Barbora de Courten

Subject: Medicine And Pharmacology, Clinical Medicine Keywords: systematic review; ADR assessment; elderly; aged-care facilities; medications monitoring; nursing home; drug review

Online: 29 February 2020 (03:41:22 CET)

Show abstract| Download PDF| Supplementary Files| Share

Preprint ARTICLE | doi:10.20944/preprints201906.0202.v1

Developing a Data Mining Based Model to Extract Predictor Factors in Energy Systems: Application of Global Natural Gas Demand

Reza Hafezi, Amir Naser Akhavan, Mazdak Zamani, Saeed Pakseresht, Shahab Shamshirband

Subject: Engineering, Mechanical Engineering Keywords: Natural gas demands; Prediction; Energy market; Genetic algorithm; Artificial neural network; Data mining.

Online: 20 June 2019 (15:58:25 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints201905.0268.v1

Study on the Spatial Pattern of Innovation Output and Influencing Factors in Guangdong-Hong Kong-Macao Greater Bay Area

Dongliang Yang, Chunfeng Li

Subject: Business, Economics And Management, Economics Keywords: Guangdong-Hong Kong-Macao Greater Bay Area; innovation sustainable development; innovation output; spatial pattern; empirical study

Online: 22 May 2019 (08:45:37 CEST)

Show abstract| Download PDF| Share

Preprint REVIEW | doi:10.20944/preprints201902.0038.v1

Does the Bilingual Advantage in Cognitive Control Exist and if so, what are Its Modulating Factors? A Systematic Review

Prof. Dr. Maurits Van den Noort, Esli Struys, Peggy Bosch, Lars Jaswetz, Benoît Perriard, Sujung Yeo, Pia Barisch, Katrien Vermeire, Sook-Hyun Lee, Sabina Lim

Subject: Social Sciences, Cognitive Science Keywords: bilingual advantage; bilingualism; cognitive control; individual differences; longitudinal studies; methodology

Online: 4 February 2019 (14:02:53 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints201901.0274.v1

Prevalence and Work-Related Factors Associated with Lower Back Musculoskeletal Disorders in Female Shellfish Gatherers in Saubara, Bahia – Brazil

Maria Carolina Barreto Moreira Couto, Ila Rocha Falcão, Juliana dos Santos Müller, Ivone Batista Alves, Wendel da Silva Viana, Verônica Maria Cadena Lima, Paulo Gilvane Lopes Pena, Courtney Georgette Woods, Rita Franco Rego

Subject: Medicine And Pharmacology, Orthopedics And Sports Medicine Keywords: musculoskeletal disorders; lower back pain; female artisanal fisher; shellfish gatherers

Online: 28 January 2019 (10:19:59 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints201809.0024.v1

Effects of Glycine in Collagen Expression and Factors Growth, Platelet (PDGF) and Epidermal (EGF) in Oral Mucositis Induced Hamster

Odara Maria de Sousa Sá, Nilza Nelly Fontana Lopes, Maria Teresa Seixas Alves, Eliana Maria Monteiro Caran

Subject: Chemistry And Materials Science, Medicinal Chemistry Keywords: oral mucositis; glycine; intercellular signaling peptides and proteins

Online: 3 September 2018 (11:09:30 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints201805.0281.v1

Construction Technology Adoption Cube: An Investigation on Process, Factors, Barriers, Drivers, and Decision Makers using NVivo and AHP Analysis

Samad Sepasgozar, Steven Davis

Subject: Engineering, Control And Systems Engineering Keywords: construction technology adoption process; construction; mining; digital technology; diffusion; implementation; mix methods; grounded theory; thematic analysis; data and methodological triangulation techniques; AHP; NVivo

Online: 22 May 2018 (04:52:39 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints201802.0152.v1

Factors Associated with Lamina Cribrosa Displacement After Trabeculectomy Measured by Optical Coherence Tomography in Advanced Primary Open Angle Glaucoma

Hamed Esfandiari, Ali Efatizadeh, Azadeh Doozandeh, Mehdi Yaseri, Nils A. Loewen

Subject: Medicine And Pharmacology, Ophthalmology Keywords: glaucoma; lamina cribrosa; optic nerve head; optical coherence tomography; corneal hysteresis; visual field; trabeculectomy

Online: 24 February 2018 (11:06:05 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints201802.0016.v1

Applicability of Commonly Accepted Factors on preventing the Pit Latrines Correlated Ground Water Contamination in Kalpitiya Peninsula, Sri Lanka

Ranjana U.K. Piyadasa, H.M.M. Sonali D. Herath

Subject: Environmental And Earth Sciences, Environmental Science Keywords: ground water; pit latrines; fecal contamination; common factors

Online: 2 February 2018 (09:06:10 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints201709.0117.v1

Significance Tests for Binomial Experiments: Ordering the Sample Space by Bayes Factors and Using Adaptive Significance Levels for Decisions

Carlos A. de B. Pereira, Adriano Polpo, Eduardo Y. Nakano

Subject: Computer Science And Mathematics, Applied Mathematics Keywords: significance level; sample size; bayes ratio; likelihood function; optimal decision; significance test

Online: 25 September 2017 (08:33:18 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints201708.0030.v1

Modeling NDVI Using Joint Entropy Method considering Hydro-Meteorological Driving Factors in the Middle Reaches of Hei River Basin

Zhang Gengxi, Xiaoling Su, Vijay P. Singh, Olusola O. Ayantobo

Subject: Environmental And Earth Sciences, Environmental Science Keywords: Joint entropy; NDVI; temperature; precipitation; groundwater depth; Hei River basin

Online: 8 August 2017 (08:42:54 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints201612.0123.v1

Using Radiofrequency Identification Automated Technologies for Predictive Analytics of Signaling Factors to Determining In-Patient Post Treatment Sleep Quality

Haley Hudson, Erick Jones, Dawit Aberra, Shalini Gupta, Felicia Jefferson

Subject: Public Health And Healthcare, Other Keywords: EMG; EEG; ECG; EOG; polysomnography

Online: 25 December 2016 (08:34:20 CET)

Show abstract| Download PDF| Supplementary Files| Share

Preprint ARTICLE | doi:10.20944/preprints202402.0890.v1

Characterization of Industrial High-Strength Aluminum Alloys by Laser-Induced Breakdown Spectroscopy, With Special Emphasis on the Detection of Low Contents of Mg, Mn, Cr, Cu, Zn and Sensing of Molecular Diatomic Emission of AlO During Ablation

Svetlana Rytchkova, Luc Lévesque

Subject: Physical Sciences, Optics And Photonics Keywords: Laser-induced breakdown spectroscopy (LIBS); Aluminum (Al); Magnesium (Mg); Manganese (Mn); Chromium (Cr); Copper (Cu); Zinc (Zn); Aluminum Monoxide (AlO).

Online: 16 February 2024 (07:01:12 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202409.1857.v1

Determinant Factors of Entrepreneurial Culture in University Students: An Analysis from the Theory of Planned Behavior at a Peruvian University

KERWIN JOSE CHAVEZ VERA, JOEL JOAB ALDERETE VELITA, TOMAS ALCALA MARTINEZ, RAUL MARCELO FERRER

Subject: Business, Economics And Management, Business And Management Keywords: Entrepreneurial culture; entrepreneurial self-efficacy; innovation; entrepreneurial intention; institutional support

Online: 24 September 2024 (05:14:08 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202409.0823.v1

The Impact of Breast Cancer Risk Factors: Socio-Economic, Hormonal, and Clinical Insights from Hassan II Regional Oncology Center, Morocco

Mouas Fatima Ezahra, Doudach Latifa, Addoum Boutaina, Attaleb Mohammed, Mohammed El Mzibri, Benbacer Laïla, Rais Ghizlane, Fechtali Taoufiq

Subject: Medicine And Pharmacology, Other Keywords: Breast cancer; socio-economic; factors; hormonal; clinical; treatments; stategies

Online: 11 September 2024 (00:14:10 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202408.2258.v1

An Analysis of Key Factors Driving Food Tourism Develop-ment: A Scenario-Based Approach in the Rural Areas of Iran

Amir Karbassi Yazdi, Davood Jamini, Hossein Komasi, Giuliani Coluccio

Subject: Social Sciences, Tourism, Leisure, Sport And Hospitality Keywords: Tourism; Tourism Development; Food Tourism; Futures Studies; Scenario Planning

Online: 30 August 2024 (15:43:54 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202408.2195.v1

Prevalence of Lower Back Pain (LBP) and its Associated Risk Factors Among Alfaisal University Medical Students in Riyadh, Saudi Arabia

Mohamad Behairy, Samir Odeh, Jouri Alsourani, Mohamad Talic, Sara Alnachef, Sadia Qazi, Muhammad Atif Mazhar, Hani Tamim

Subject: Public Health And Healthcare, Public, Environmental And Occupational Health Keywords: Lower Back Pain; Medical Students; Saudi Arabia; Prevalence; Oswestry Disability Index; Ergonomics; Physical Activity; Risk Factors; Disability

Online: 29 August 2024 (16:17:53 CEST)

Show abstract| Download PDF| Supplementary Files| Share

Preprint ARTICLE | doi:10.20944/preprints202408.0629.v1

Adult Respiratory Syncytial Virus Infection: Defining Incidence, Risk Factors for Hospitalization and Poor Outcomes, A Regional Cohort Study, 2016-2022

Tal Brosh-Nissimov, Daniel Ostrovsky, Amos Cahan, Nir Maaravi, Daniel Leshin-Carmel, Nitzan Burrack, Rotem Gorfinkel, Lior Nesher

Subject: Medicine And Pharmacology, Epidemiology And Infectious Diseases Keywords: Respiratory syncytial virus (RSV); Incidence; hospitalization; Adult; Epidemiology; Influenza

Online: 9 August 2024 (10:16:25 CEST)

Show abstract| Download PDF| Supplementary Files| Share

Preprint ARTICLE | doi:10.20944/preprints202407.2441.v1

Understanding Risk Factors of Recurrent Anxiety Symptomatology in an Older Population with Mild to Severe Depressive Symptoms: A Bayesian Approach

Eduardo Maekawa, Mariana Martins, Carina Akemi Nakamura, Ricardo Araya, Tim J Peters, Pepijn Van De Ven, Marcia Scazufca

Subject: Computer Science And Mathematics, Artificial Intelligence And Machine Learning Keywords: Bayesian network; machine learning; anxiety; older population; clinician

Online: 30 July 2024 (13:42:56 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202407.0774.v1

A Retrospective Analysis of Breast Cancer Mortality among Jewish and Muslim Arab Women in Israel: The Role of Sociodemographic Factors

Ronit Pinchas-Mizrachi, Dan Bouhnik

Subject: Public Health And Healthcare, Public Health And Health Services Keywords: Breast cancer mortality; ethnic disparities; socioeconomic status; reproductive factors; Israeli women; health inequalities

Online: 10 July 2024 (10:48:28 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202407.0507.v1

Chest X-Ray Findings and Prognostic Factors in Survival Analysis in Peritoneal Dialysis and Hemodialysis Patients: A Retrospective Cohort Study

Nilgün Tan Tabakoglu, Osman Nuri Hatipoglu

Subject: Medicine And Pharmacology, Other Keywords: Peritoneal dialysis; Hemodialysis; Etiology; Mortality; Survival; Chest radiography

Online: 5 July 2024 (09:47:57 CEST)

Show abstract| Download PDF| Share

Background and Objectives: To analyze survival in peritoneal and hemodialysis patients using chest radiography and biochemical parameters, determine dialysis etiologies and common mortality causes, reveal prognostic factors, and contribute to clinical practice. Materials and Methods: This retrospective cohort study was based on the analysis of data from 33 peritoneal dialysis and 37 hemodialysis patients who were followed and treated in our hospital between October 2018 and February 2020. Chest X-ray measurements (cardiothoracic index, pulmonary vascular pedicle width, right pulmonary artery diameter, diaphragmatic height) and biochemical parameters (urea, albumin, creatinine, parathormone, ferritin, hemoglobin, arterial blood gas, potassium) were analyzed to assess their impact on survival. Statistical analyses were performed using the Shapiro-Wilk, Wilcoxon signed rank test, Mann-Whitney U test, McNemar test, Kaplan-Meier survival analysis, Cox regression analysis, Spearman correlation test, Phi test, and ROC analysis. Results: The most common etiologies of dialysis were hypertension, type 2 diabetes mellitus, and urogenital disorders. The most common cause of death in peritoneal dialysis patients was peritonitis (38.5%), while in hemodialysis patients, it was cardiovascular diseases (47.4%). In chest X-ray measurements, pulmonary vascular pedicle width (p=0.003) and pulmonary artery diameter increased significantly (p=0.002) in hemodialysis patients, while pulmonary vascular pedicle width (p=0.028) and diaphragmatic height (p=0.004) increased significantly in peritoneal dialysis patients. No significant difference was found between the two groups in terms of biochemical parameters. Kaplan-Meier survival analysis showed that there was no significant difference in survival between peritoneal dialysis and hemodialysis methods (P>0.05). Significant correlations were found between both radiologic status and clinical status and between intact parathormone levels and pulmonary vascular pedicle width (p=0.016, p=0.024). In Cox regression analysis, age, intact parathormone levels, iPTH/PVPW ratio, and clinical status were found to be factors affecting survival (p

Preprint ARTICLE | doi:10.20944/preprints202407.0326.v1

Evaluation of Urban Resilience and Its Influencing Factors: Case Study of the Yichang-Jingzhou-Jingmen-Enshi Urban Agglomeration in China

Zhilong Zhao, Zengzeng Hu, Xu Han, Lu Chen, Zhiyong Li

Subject: Environmental And Earth Sciences, Sustainable Science And Technology Keywords: urban resilience; spatio-temporal differentiation; influencing factors; Yichang-Jingzhou-Jingmen-Enshi urban agglomeration; China

Online: 3 July 2024 (11:29:47 CEST)

Show abstract| Download PDF| Share

In the context of global urbanization and climatic change, the frequency of various uncertainties and disturbances faced by urban system is increasing, and enhancing urban resilience has become one of the vital components of sustainable development of modern cities. At the same time, urban resilience has become a hot topic in interdisciplinary research such as economics, ecology, and geography. This paper constructs urban resilience evaluation indicator system based on four dimensions—economy, ecology, society, and infrastructure. The evaluation indicator is used to measure the resilience levels of Yichang-Jingzhou-Jingmen-Enshi (YJJE) urban agglomeration in China from 2010 to 2023. Using the entropy weight method, the Getis-Ord Gi* model, and the robustness testing, this paper analyzes the spatiotemporal evolution characteristics of urban resilience in YJJE urban agglomeration. Then, the factor contribution model is used to explore the influencing factors of urban resilience. Finally, the CA-Markov model is used to predict urban resilience in 2030. The results are as follows: From 2010 to 2023, the urban resilience values of all prefecture-level and county-level cities in YJJE urban agglomeration showed an upward trend, and it indicated that the resilience of urban system is improving. Meanwhile, the urban resilience of YJJE urban agglomeration increased with an average annual growth rate of 3.25%. Furthermore, the urban resilience exhibited a significant spatially heterogeneity distribution, with Xiling, Wujiagang, Xiaoting, Yidu, Zhijiang, Dianjun, Dangyang, Yuan’an, Yiling, Duodao being the high-value agglomerations of urban resilience, and Hefeng, Jianli, Shishou, Wufeng being the low-value agglomerations of urban resilience. Then, we identified critical driving factors of urban resilience in YJJE urban agglomeration. Finally, the urban resilience of all cities within YJJE urban agglomeration will reach the medium level or higher than medium level in 2030. Xiling, Wujiagang, Xiaoting, Zhijiang, Dianjun, Dangyang, Yuan’an will remain hot spots of urban resilience, while Jianli will remain cold spots of urban resilience in the future. This study can provide the scientific reference and policy recommendation for the government to build resilient cities and improve sustainable urban development.

Preprint DATA DESCRIPTOR | doi:10.20944/preprints202406.1685.v1

The Incidence of Respiratory Infections and Nutritional Deficiency in Chadian Under-Five Female and Male Children: Trends and Risk Factors

Martial Nodjimadji Tamlengar, Ngaba Neguemadji Ngardig, Sweetyben Patel, Lidya Metekia, Imteyaz Ahmad Khan, Amit Gulati, Sakshi Khurana, Ousmane Ahmat Mahamat

Subject: Public Health And Healthcare, Public Health And Health Services Keywords: Lower respiratory infections 1; Upper respiratory infections 2; Nutritional deficiency 3; Under-5 children 4; Maternal health and environmental risk factors 5; Chad 6.

Online: 24 June 2024 (11:48:23 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202406.1563.v1

Exploring Sustainable Factors Shaping Sustainable Value Creation In Managing Transit Oriented Development Area Mass Rapid Transit: A Systematic Literature Review

Zulfadli Ardiansyah, Marimin Marimin, Yurianto Yurianto, Dikky Indrawan

Subject: Business, Economics And Management, Business And Management Keywords: Sustainable; Value Creation; VRIO; Transit Oriented Development; Mass Rapid Transport; Systematic Literature Review

Online: 24 June 2024 (07:31:00 CEST)

Show abstract| Download PDF| Share

Preprint BRIEF REPORT | doi:10.20944/preprints202406.1384.v1

A Brief Report on the Caregiver Burden: Exploring the Risk and Psychological Factors in Caregivers of Patients with Parkinson’s Disease

Luna Carpinelli, Giulia Savarese, Ettore Luisi, Francesca Pellegrino, Maria Teresa Pellecchia

Subject: Social Sciences, Psychology Keywords: Caregiver burden; Parkinson's disease; Quality of life; psychiatric morbidity; anxiety-depressive distress.

Online: 20 June 2024 (10:03:31 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202406.0577.v1

Factors Associated With Complications of Snakebite Envenomation in Health Facilities in the Cascades Region of Burkina Faso, 2016 to 2021

Réné Kinda, Sidikiba Sidibe, Dramane Zongo, Tieba Millogo, Alexandre Delamou, Seni Kouanda

Subject: Public Health And Healthcare, Public Health And Health Services Keywords: Snakebite; Envenomation; Complications

Online: 11 June 2024 (08:48:50 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202405.1919.v1

Under-Five Mortality and Associated Risk Factors in Children Hospitalized at David Bernardino Pediatric Hospital (DBPH), Angola: A Hierarchical Approach

Israel Avelino, Joaquim Van-Dúnem, Luís Varandas

Subject: Medicine And Pharmacology, Pediatrics, Perinatology And Child Health Keywords: under-five mortality; hierarchical approach; risk factors; case-control studies; hospitalization; logistic regression

Online: 29 May 2024 (07:47:32 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202405.1093.v1

The Hidden Hunger among Nepalese Non-pregnant Women Aged 15–49 Years: The Role of Individual, Household, Community-Level Factors

Kingsley Emwinyore Agho, Stanley Chitekwe, Biniyam Sahiledengle, Lucy Ngaihbanglovi Pachuau, Sanjay Rijal, Naveen Paudyal, Sanjeev Kumar Sahani, Andre Renzaho

Subject: Public Health And Healthcare, Nursing Keywords: Micronutrients; women; deficiencies; non-pregnant women; Nepal

Online: 16 May 2024 (13:43:06 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202404.1771.v1

Exploring Predictive Factors for Heart Failure Progression in Hypertensive Patients Based on Medical diagnosis Data from the MIMIC-IV Database

Jinmyung Jung, Doyoon Kim, Inkyung Hwang

Subject: Public Health And Healthcare, Public Health And Health Services Keywords: heart failure; hypertension; predictive factors; MIMIC-IV database; data mining; XGBoost modeling; chi-square test

Online: 26 April 2024 (20:12:01 CEST)

Show abstract| Download PDF| Supplementary Files| Share

Preprint ARTICLE | doi:10.20944/preprints202404.0963.v1

Retrospective Study on the Risk Factors for Resuscitation at Birth and Admission to the NICU in a Third Level Maternity

Florica Ramona Dorobanțu, Nicolae Ovidiu Pop, Dana Carmen Zaha, Dorina Gabriela Dascal, Ioana Coralia Codreanu, Carmen Pantiș, Parascovia Pop, Cătălin Dorin Dorobanțu

Subject: Public Health And Healthcare, Other Keywords: newborn; risk factors; resuscitation; emergency.

Online: 15 April 2024 (11:32:28 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202404.0314.v1

Impact of Psychosocial Factors on Crohn's Disease Activity: A Cross-Sectional Analysis of Social Support, Stress, and Flare-Up Incidence

María José de Dios-Duarte, Andrés Arias, Ana Barrón

Subject: Public Health And Healthcare, Public Health And Health Services Keywords: Social Support; Stress; Crohn's disease; Flare-up

Online: 3 April 2024 (15:46:02 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202403.0209.v1

Estimating the influencing factors of Gas-Water Relative Permeability in Condensate Gas Reservoirs under High-Temperature and High-Pressure Conditions

Shuheng Cui, QiLin Wu, Zixuan Wang

Subject: Engineering, Energy And Fuel Technology Keywords: gas-water relative permeability; high temperature; high pressure; condensate gas reservoir; influencing factors

Online: 5 March 2024 (10:57:23 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202402.0237.v1

Prevalence, Resistance Profiles and Factors Associated with Skin and Soft-Tissue Infections at Jinja Regional Referral Hospital: A Retrospective Study

Fahad Lwigale, Daniel Kibombo, Simon Dembe Kasango, Dickson Tabajjwa, Joseph Kungu, John Bosco Kalule, Morgan Otita, Francis Kakooza, Immaculate Nabukenya, Jonathan Mayito, Innocent B. Rwego

Subject: Public Health And Healthcare, Public Health And Health Services Keywords: skin and soft-tissue infections; antimicrobial resistance; multidrug-resistance; hospital-acquired infections; global antimicrobial resistance surveillance system

Online: 5 February 2024 (07:28:57 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202401.1799.v1

Suboptimal Nutritional Status of School-Age Children in Addis Ababa: Evidence from the Analysis of Sociodemographic, Environmental, and Behavioral Factors

Yimer Mihretie Mihretie, Abebe Ayelign, Tadesse Alemu Zerfu

Subject: Public Health And Healthcare, Public Health And Health Services Keywords: ; Addis Ababa; dietary factors; nutritional status; school-age children

Online: 25 January 2024 (09:53:52 CET)

Show abstract| Download PDF| Share

Preprint REVIEW | doi:10.20944/preprints202401.0075.v1

Harmonizing Learning Spaces: A Comprehensive review of Environmental Factors in Italian Schools with a Focus on the Impact of Acoustics

Samantha Di Loreto, Sergio Montelpare

Subject: Engineering, Other Keywords: Acoustic Comfort; Indoor Air Quality; Thermal Comfort; Ventilation; Visual Comfort; Heat storage; ISO Standards

Online: 2 January 2024 (09:44:00 CET)

Show abstract| Download PDF| Share

Preprint COMMUNICATION | doi:10.20944/preprints202401.0057.v1

Use of Remote Sensing and Biogeochemical Modelling to Simulate the Impact of Climatic and Anthropogenic Factors on Forest Carbon Fluxes

Marta Chiesi, Luca Fibbi, Silvana Vanucci, Fabio Maselli

Subject: Environmental And Earth Sciences, Remote Sensing Keywords: forest ecosystem; GPP; NEP; Modified C-Fix; BIOME-BGC.

Online: 2 January 2024 (08:36:08 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202312.1936.v1

Studying for Characterization of Ovarian Development and Associated Factors during the Breeding Migration of Coilia nasus in the Yangtze River

Shuwei Wei, Zhong Hua, Yanping Yang, Fengjiao Ma, Wei Han, Wei Zhang, Congping Ying, Yanmin Deng, Kai Liu

Subject: Biology And Life Sciences, Aquatic Science Keywords: Coilia nasus; ovarian development; organizational observation; sex steroid hormones; gene expression

Online: 26 December 2023 (06:59:53 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202312.1731.v1

Circuit training improves the levels of Aβ and BDNF related to cognitive impairment risk factors in obese elderly Korean women

Duwang Kang, Suhan Koh, Taekyu Kim, Eadric Bressel, Do-yeon Kim

Subject: Medicine And Pharmacology, Clinical Medicine Keywords: circuit training; β-amyloid; BDNF; cognitive function; obese elderly women

Online: 22 December 2023 (10:20:35 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202312.1180.v1

Demystifying the Factors Contributing to Alienation and Fostering Social Justice in Higher Education: A Case of First-Year University Students

Innocent Zitha, Georgina Mokgaetji Mokganya, Takalani Yolanda Tshililo

Subject: Arts And Humanities, Humanities Keywords: Estrangement; Acculturation; Assimilation; Student dropout; Under- preparedness

Online: 15 December 2023 (11:11:20 CET)

Show abstract| Download PDF| Share

Preprint REVIEW | doi:10.20944/preprints202311.1752.v1

Wen Ting Tong, Ananta Seth, Mary Ng, Shao Chuen Tong, Amanda Lau, Tina Chen, Suan Ee Ong, Joanne Yoong

Subject: Public Health And Healthcare, Public Health And Health Services Keywords: vaccine uptake; immunisation; adults; older people; elderly; Asia-Pacific; barriers; facilitators; factors; interventions

Online: 28 November 2023 (07:15:38 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202311.1617.v1

Asymmetry of Motifs Conservation within Homotypic Composite Elements Differentiates DNA-Binding Domains of Target Transcription Factors in ChIP-Seq Data

Victor G. Levitsky, Vladimir V. Raditsa, Anton Tsukanov, Aleksey M. Mukhin, Tatyana I Merkulova

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: Chromatin immunoprecipitation followed by sequencing; transcription factors binding sites prediction; cooperative binding of transcription factors; motifs conservation; classification of transcription factors; direct binding of transcription factors

Online: 27 November 2023 (07:26:54 CET)

Show abstract| Download PDF| Supplementary Files| Share

Preprint ARTICLE | doi:10.20944/preprints202311.0725.v1

Factors Associated with Candidiasis in Pemphigus Vulgaris Patients: Results from a Retrospective Study in Two Second‐Care Hospitals in Mexico

Andrés Tirado-Sánchez, Alexandro Bonifaz, María Guadalupe Frías De León

Subject: Medicine And Pharmacology, Epidemiology And Infectious Diseases Keywords: pemphigus vulgaris; neutrophil-lymphocyte ratio; platelet-neutrophil ratio; corticosteroids; candidiasis; candidemia

Online: 13 November 2023 (08:37:11 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202311.0266.v1

Genetic Alterations and Risk Factors for Recurrence in Patients with Non-Small Cell Lung Cancer Who Underwent Complete Surgical Resection

Hwa Kyung Park, Yoo Duk Choi, Ju-Sik Yun, Sang-Yun Song, Kook-Joo Na, Joon Young Yoon, Chang-Seok Yoon, Hyung-Joo Oh, Young-Chul Kim, In-Jae Oh

Subject: Medicine And Pharmacology, Pulmonary And Respiratory Medicine Keywords: Lung neoplasm, early stage, epidermal growth factor receptor

Online: 6 November 2023 (09:26:40 CET)

Show abstract| Download PDF| Share

Definitive surgical resection is the preferred treatment for early-stage non-small-cell lung cancer (NSCLC). Research into genetic alterations, including epidermal growth factor receptor (EGFR) mutation, in early stage NSCLC remains insufficient. Here, we investigated the prevalence of genetic alterations in early-stage NSCLC and the association between EGFR mutation and recurrence after complete resection. Between January 2019 and December 2021, 659 patients with NSCLC who underwent curative surgical resection at a single regional cancer center were recruited. We compared the clinical and pathological data between the recurrence and non-recurrence groups. Multivariate logistic regression was used to predict the risk factors for recurrence. Among the 659 enrolled cases, the most common histology was adenocarcinoma (74.5%), followed by squamous cell carcinoma (21.7%). The prevalence of EGFR mutation was 43% (194/451). Among them, L858R point mutation and exon 19 deletion was 52.3% and 42%, respectively. ALK rearrangement was found at 5.7% (26/453), and ROS1 fusion was found at 1.6% (7/441). The recurrence rate of the entire population was 19.7%. In multivariate analysis, the presence of EGFR mutation, stage II or III (vs. stage I), and pathologic subtype (presence of solid type) were associated with recurrence. Among the recurred group, 86.5% of the patients with EGFR mutation experienced distant recurrence compared to only 66.7% of wild-type (p = 0.016), with no significant difference in median disease-free survival (p = 0.983). In conclusion, the prevalence of EGFR mutation, ALK rearrangement, and ROS1 fusion was 43.0%, 5.7%, and 1.6%, respectively in patients with early-stage NSCLC who underwent curative resection. Along with stage II/III and solid pathologic subtype, EGFR mutation was an independent risk factor for recurrence. In the recurrence group, the rate of distant metastasis was higher in patients with EGFR mutation than in those with wild-type.

Preprint ARTICLE | doi:10.20944/preprints202310.0786.v1

Factors Affecting Exclusive Breastfeeding Practices among Working Class Women Attending Antenatal Clinic in Egbedore Local Government Area, Osun State, Nigeria

Ruth T. Abioye, Adeyemi O. Omoge, Olawumi J. Ajao, Blessing O Olatunji, Elizabeth O. Olatunji, Oluwatoromoleyin M. Olamide, Adedapo O. Dada

Subject: Public Health And Healthcare, Primary Health Care Keywords: Exclusive breastfeeding, Working class, Women, Knowledge.

Online: 13 October 2023 (08:27:52 CEST)

Show abstract| Download PDF| Share

Background: Exclusive breastfeeding (EBF) for the first 6 months of life improves the growth, health and survival status of newborns. Breastfeeding has been accepted as the most vital intervention for reducing infant mortality and ensuring optimal growth and development of children. Objectives: The general objective was to identify the factors affecting exclusive breastfeeding among working class women in selected wards in Egbedore Local Government in Osun state, Nigeria. Methodology: This was descriptive cross-sectional study. Leslie Kish formula was used for sample size calculation and multistage sampling was used in selecting 316 working class women for the study. A structured, self-administered questionnaire was used for data collection. Data was analyzed using SPSS version 21.0 and level of significance was set at 5%. Results: 58% of the respondents were between the ages of 25-30. 72% demonstrated good understanding of exclusive breastfeeding based on the 6 months WHO recommendation for exclusive breast feeding, 25.9% had a fair knowledge and awareness of exclusive breastfeeding. 63.3% of the working class mother has a good practice of exclusive breast feeding, 19.6% of the women moderately practices exclusive breastfeeding while 17.1% poorly practices exclusive breastfeeding. Less than 3-months maternity leave for mothers, lack of crèche closer to place of work and lack of breastfeeding break were identified as barriers to exclusive breastfeeding practices among the working class women. The findings demonstrated a significant relationship between knowledge and practices of exclusively breastfeeding among working class women (P-value .009). Conclusion: This study demonstrated that working class women had good knowledge of exclusive breastfeeding and this influenced their breastfeeding practices. A good knowledge was associated with favorable attitudes to the practice of exclusive breast feeding. To derive long-term benefits from early childhood nutrition, interventions should focus on health education and community-based sensitization programs on the needs for mothers to engage in exclusive breast needing for global development.

Preprint ARTICLE | doi:10.20944/preprints202308.0179.v1

Influence of Various Factors on the Structure of Fibriallar Matrices Based on Ultrafine Poly-3-Hydroxybutyrate Fibers Obtained by Electrospinning

A. A. Olkhov, Tyubaeva P.М., Yulia Zernova, Valery Markin, Regina Kosenko, Anna G. Filatova, Kristina G. Gasparyan, Alexey L. Iordanskii

Subject: Chemistry And Materials Science, Materials Science And Technology Keywords: poly-3-hydroxybutyrate; fibers; electrospinning; solution parameters; dipyridamole; Fe(III)Cl tetraphenyl porphyrin complex; structure

Online: 2 August 2023 (09:59:45 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202307.1714.v1

Epidemiological Trends in Cardiovascular Disease Mortality Attributable to Modifiable Risk Factors and Its Association with Sociodemographic Transition across BRICS-Plus

Nawsherwan ---, Sumaira Mubarik, Wang Bin, Zhang Le, Mangmang Sang, Yijun Lin, Jinrong Zheng, Yan Wang

Subject: Public Health And Healthcare, Public Health And Health Services Keywords: Cardiovascular diseases; mortality; modifiable risk factors; sociodemographic index; BRICS-Plus

Online: 25 July 2023 (11:32:10 CEST)

Show abstract| Download PDF| Supplementary Files| Share

Preprint ARTICLE | doi:10.20944/preprints202307.1335.v1

Factors Associated with Late Diagnosis of HIV/AIDS in a University Hospital in Brazil: Challenges to Achieving the 2030 Target

Ligia Maria Nascimento Arantes, Andrey Oeiras Pedroso, Mayra Gonçalves Menegueti, Elucir Gir, Eliã Pinheiro Botelho, Ana Cristina de Oliveira e Silva, Renata Karina Reis

Subject: Medicine And Pharmacology, Clinical Medicine Keywords: HIV; Acquired Immunodeficiency Syndrome; late diagnosis; Nursing

Online: 19 July 2023 (11:40:18 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202307.0704.v1

Developing the Social Ecology of Occupational Zoonoses Instrument: A Comprehensive Tool for Measuring Social and Behavioral Factors in Agricultural Settings

Jairo E. Palomares Velosa, Sangeeta Rao, Ivette N. Roman-Muniz, Katie Steneroden, Mo D. Salman

Subject: Public Health And Healthcare, Public, Environmental And Occupational Health Keywords: Instrument; questionnaire; survey; measurement validity evidence; AERA/APA standards; occupational risks; zoonotic diseases; Social Ecological Model; prevention

Online: 11 July 2023 (09:55:17 CEST)

Show abstract| Download PDF| Supplementary Files| Share

Preprint ARTICLE | doi:10.20944/preprints202306.2173.v1

Spatiotemporal Dynamics of Cropland Area and Its Driving Factors in the Farming-Pastoral Ecotone of Northern China during 1992−2020

Wencun Zhou, Zhengjia Liu

Subject: Environmental And Earth Sciences, Geography Keywords: Cropland area trend; Contribution rate; Ridge regression model; Extreme events; Ecological construction; Urban expansion

Online: 30 June 2023 (07:20:11 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202306.2112.v1

Risk Factors and Outcomes of Children with Congenital Heart Disease on Extracorporeal Membrane Oxygenation, a 10-Year Single-Center Report

Antonio Amodeo, Milena Stojanovic, Tugba Erdil, Hitendu Dave, Robert A. Cesnjevar, Sebastian Paal, Oliver Kretschmar, Martin Schweiger

Subject: Medicine And Pharmacology, Cardiac And Cardiovascular Systems Keywords: ongenital heart disease; extracorporeal life support; ECMO; single ventricle; complications; risk factors; mortality

Online: 30 June 2023 (03:41:18 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202306.1333.v1

CGT Feeding Amid Feed Scarcity in Sheep and Factors Driving Inclusion in Yarn Spinning Industrial Cluster of Tamil Nadu, India

Sri Balaji N, Ramakrishnan S, Muralidharan J, Vasan P, Thiruvenkadan A K T, Sivakumar K, Sankar V, Kumaravel V, Thirunavukkarasu D

Subject: Biology And Life Sciences, Animal Science, Veterinary Science And Zoology Keywords: Cotton gin trash (CGT); Feeding practices; Feed scarcity; Non-Conventional feed resources (NCFR); Sheep farming

Online: 19 June 2023 (09:05:49 CEST)

Show abstract| Download PDF| Share

CGT is composed of fiber residues, leaves, dust particles, soil and others derived during the ginning and yarn spinning process at processing industries,. In the cotton spinning industrial clusters, farmers are using CGT) as one of the alternative roughage feed for their sheep, mainly during forage shortages in the summer months. To have baseline information on farmers using gin and factors driving them to choose CGT as a roughage source, which need to be identified for future planning on the usage of CGT in sheep feeding. Considering the above facts, the present study was undertaken to assess socio-personal characteristics, managemental practices associated with farmers using cotton gin in the feeding of sheep and also identify the factors driving the choice of the CGT as the primary source of roughage in the cotton spinning industry cluster of Tamil Nadu. For this, a survey among 80 sheep farmers was carried out using a pre-tested in-terview schedule. The collected data was analysed using descriptive statistics and logit regres-sion. The results indicated that the majority of male, aged, and large-land farmers were involved in practicing CGT feeding during the summer and also indicated the non-availability of green fodder during the summer season. The coarse type of CGT preferred more than the fine type of CGT trash in that area due to quality perception and price. The replacement level of CGT as roughage ranged from 33 to 75% of the total roughage requirement per day. About 88 percent-age of farmers were highly satisfied with the results of using CGT and they also expressed that the presence of foreign particles and dust were the major problems with using CGT. The choice of CGT as primary roughage among sheep farmers was primarily influenced by selective farming contexts, namely landholding, access to labour, and feeding practices of other livestock with cotton gin. Further, research has to be focused on to improve the quality of CGT in the future, as it is being utilised largely by sheep farmers.

Preprint ARTICLE | doi:10.20944/preprints202306.0542.v1

Geographical Factors Determining the Transmission of COVID-19: Lessons Learned from Turkish Black Sea Region to Face Next Pandemic Crisis

Aytac Perihan Akan, Mario Coccia

Subject: Social Sciences, Other Keywords: COVID-19; Coronavirus Disease; SARS-CoV-2; Humidity; Rainfall; Coastal regions; Pandemic plans; Health Policy

Online: 7 June 2023 (11:03:07 CEST)

Show abstract| Download PDF| Supplementary Files| Share

Preprint ARTICLE | doi:10.20944/preprints202306.0369.v1

Factors of Sustainable Consumption Behavior Based on Health Risk Perception: The Example of Electronic Vehicles in Kunming, Yunnan Province, China

Yuexin Dou, Ji Chen

Subject: Social Sciences, Behavior Sciences Keywords: sustainable consumption behavior; electronic vehicles; SEM; Kunming

Online: 6 June 2023 (03:50:11 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202305.1690.v1

Association of Positive Hepatitis B Serology Markers With Risk and Behavior Factors in Kazakhstan Blood Donors: A Cross Sectional Study

Tatyana Savchuk, Yelena Grinvald, Mohamed Ali, Ramune Sepetiene, Saniya Saussakova, Kuralay Zhagazieva, Dulat Imashpayev, Saniya Abdrakhmanova

Subject: Biology And Life Sciences, Virology Keywords: hepatitis B; anti HBcore; risk factors; blood donors

Online: 24 May 2023 (04:37:56 CEST)

Show abstract| Download PDF| Share

Background and Aim. Recently made analysis for anti-HBcor prevalence within Kazakhstan blood donors population concluded 17.2% rate. Considering these data are among the highest of infectivity results worldwide, an objective of this study was to define an association of positive Hepatitis B serology markers with risk and behavior factors. Methods. The blood donors’ samples were tested for anti-HBcore total (IgG/IgM) and anti-HBs, by CLIA on the Architect i2000SR platform (Abbott). Surrogate alanine transferase (ALT) markers for all blood donors were tested by kinetic method on the Biosystems A25 analyzer. A questionnaire was developed for socio-demographic characteristics, donors’ nutrition habits, cholesterol levels and history of smoking, alcohol consumption. Informed consent was obtained from all study participants. Statistics was calculated using the R software program (version 4.1.1, USA, 2021). Results. A group of 5709 blood donors participated in the study. Participants with positive anti-HBcore scores were on average older (41.8 vs 34.4 years, p<0.001), Kazakh (88.7% vs 83.0%, p<0.001), married (74.0% vs 55.6%, p<0.001), had a secondary education (70.1% vs. 59.4%, p=0.03), smoked (27.9% vs. 24.3%, p=0.05), had a longer smoking history (13.6±9.5 years vs. 9.8±8.5 years, p<0.001), and various hypercholestesterolaemia (6.2% vs 3.9%, p=0.02). Predominantly their main meal was dinner (17.0% vs 14.2%, p=0.03). Analysis for associations of socio-demographics characteristics, risk factors, nutrition with anti-HBs, showed that those who have secondary education level (70.1%) were more likely to be anti-HBs-positive (p=0.03). No other significant correlations for anti-HBs were observed. Conclusions. The risk factors and behavior analysis highlighted the blood donors’ overall health status. Positive Hepatitis B markers associated with statistically significant characteristics from socio-demography, nutrition habits or risk factors could support further pathogenesis studies looking for HBV treatment guides fulfilling the existing gaps.

Preprint ARTICLE | doi:10.20944/preprints202305.1181.v1

Influenza Vaccination Uptake and Prognostic Factors Among Health Professionals in Italy: Results From the Nationwide Sur-Veillance PASSI 2015–2018

Valentina Minardi, Rosaria Gallo, Valentina Possenti, Benedetta Contoli, Davide Di Fonzo, Elvira D’Andrea, Maria Masocco

Subject: Public Health And Healthcare, Public Health And Health Services Keywords: influenza vaccination; health personnel; health care worker; surveillance system; epidemiology; prevention; public health

Online: 17 May 2023 (04:27:18 CEST)

Show abstract| Download PDF| Supplementary Files| Share

Preprint ARTICLE | doi:10.20944/preprints202305.0679.v1

Factors Informing the Development of a Clinical Pathway and Quality of Life Post Non-union Fractures of the Lower Limb

Nontembiso Magida, Hellen Myezwa, Witness Mudzi

Subject: Public Health And Healthcare, Public Health And Health Services Keywords: clinical pathways; lower limbs; quality of life; non-union fractures

Online: 10 May 2023 (04:00:12 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202305.0243.v1

Unraveling the Green Growth Matrix: Exploring the Impact of Green Technology, Climate Change Adaptation, and Macroeconomic Factors on Sustainable Development

Busra Agan, Mehmet Balcilar

Subject: Business, Economics And Management, Economics Keywords: green growth; green technology; technology diffusion; climate change adaptation; sustainable development; panel data

Online: 4 May 2023 (09:03:36 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202302.0008.v1

Factors Associated with Extended Length of Stay for Paediatric Mental Health Presentations to Emergency Departments in South Western Sydney, Australia

Jahidur Rahman Khan, James Rufus John, Paul M. Middleton, Yao Huang, Ping-I Lin, Nan Hu, Bin Jalaludin, Paul Chay, Raghu Lingam, Valsamma Eapen

Subject: Medicine And Pharmacology, Psychiatry And Mental Health Keywords: extended length of stay; emergency department; mental health

Online: 1 February 2023 (06:01:41 CET)

Show abstract| Download PDF| Supplementary Files| Share

Background: Evidence suggests that children and young people (CYP) who present to the emergency department (ED) for mental health (MH) difficulties may have extended lengths of stay (LOS); however, there is a paucity of research in Australia regarding the factors associated with extended LOS. This study aimed to determine the factors associated with extended LOS for paediatric MH-related presentations to the EDs in South Western Sydney (SWS), a multicultural community in Australia. Methods: We analysed electronic medical records (eMR) of 7,409 MH-related ED encounters of CYP aged 0 up to 18 years from all six public hospitals in SWS from January 2016 to April 2022. Extended LOS was defined as encounters of more than 4 hours. We assessed factors associated with extended LOS using a multilevel logistic regression model, accounting for hospital-level clustering. Results: Approximately 57.6% of all ED presentations for paediatric MH involved extended LOS. ED presentations by adolescents (adjusted odds ratio (AOR) 2.23, 95% CI 1.20-4.17 for 12-14 years and AOR 2.69, 95% CI 1.44-5.00 for 15-17 years), and patients with a preferred language other than English (AOR 1.47, 95% CI 1.15-1.89) had increased odds of extended LOS compared to their counterparts. Deliberate self-harm related presentations, the most commonly presented MH condition, had higher odds of extended LOS than other MH-related presentations (AOR 1.77, 95% CI 1.59-1.98). Patients with MH presentations that required urgent evaluation (triage levels 1-2) had higher odds of extended LOS (AOR 1.38, 95% CI 1.15-1.65) compared to triage level 3, whereas those with triage levels 4-5 had lower odds (AOR 0.66, 95% CI 0.58-0.74). Further, patients with MH-related presentations that came by ambulance (compared to other mode of presentations) and presentations that happened at night and late at night (compared to early morning and daytime presentations). The odds of extended LOS were considerably lower during the COVID-19 period compared to the pre-COVID-19 period (AOR 0.74, 95% CI 0.67-0.82). Additionally, extended paediatric LOS for MH issues in the ED showed notable hospital-level heterogeneity. Conclusion: A large proportion of extended LOS in ED and sociodemographic disparities reflect inequality in access to paediatric MH care. Our findings highlight the need for equitable distribution of resources directed towards at-risk CYP to improve MH outcomes and reduce health system burden.

Preprint ARTICLE | doi:10.20944/preprints202301.0194.v1

Something Still Remains: Factors Affecting Tsunami Risk Perception on the Coasts Hit by the Reggio Calabria – Messina 1908 Event (Italy)

Andrea Cerase, Lorenzo Cugliari

Subject: Social Sciences, Sociology Keywords: tsunami; risk communication; risk perception; local knowledge; media; scientific communication; 1908 Reggio Calabria - Messina Earthquake and tsunami

Online: 11 January 2023 (03:41:55 CET)

Show abstract| Download PDF| Supplementary Files| Share

Preprint ARTICLE | doi:10.20944/preprints202211.0496.v1

Factors Associated with Treatment Outcomes among Patients Living with HIV and Hypertension Comorbidity in the Eastern Cape Province, South Africa

Monwabisi Faleni, Sikhumbuzo A. Mabunda, Ncane Ziphelele, Guillermo Alfredo Pulido Estrada, Teke Apalata, Sibusiso Cyprian Cyprian Nomatshila

Subject: Medicine And Pharmacology, Epidemiology And Infectious Diseases Keywords: hypertension, comorbidity, HIV, antiretroviral treatment, treatment outcomes

Online: 28 November 2022 (06:04:48 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202205.0408.v2

Physician’s Hesitancy in Treating COVID-19 Patients and Its Associated Occupational Risk Factors in Indonesia: An Online Cross-Sectional Survey

Dewi Sumaryani Soemarko, Aria Kekalih, Ari Fahrial Syam, Evy Yunihastuti, Herikurniawan Herikurniawan, Mikhael Yosia

Subject: Medicine And Pharmacology, Other Keywords: hesitancy; covid-19; post-covid; medical doctors; indonesia

Online: 13 September 2022 (05:13:14 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202208.0499.v1

Variables Influencing the Pressure and Volume of the Pulmonary Circulation as Risk Factors for Developing High Altitude Pulmonary Edema (HAPE)

Thomas Küpper, Christian Apel, Daniela Bertsch, Michael Van der Giet, Simone Van der Giet, Maren Graß, Carina Gschwandtl, Nikole Heussen, Christian Kühn, Miriam Hundt, Julia Risse, Sonja Schmitz, Lisa Timmermann, Knut Wernitz, Ulf Gieseler, Audry Morrison, Nina Hundt

Subject: Medicine And Pharmacology, Pulmonary And Respiratory Medicine Keywords: HAPE; risk factors; echocardiography; pulmonary pressure; workload

Online: 30 August 2022 (03:18:35 CEST)

Show abstract| Download PDF| Share

Background: At altitudes beyond 2500 m the risk of developing high altitude pulmonary edema (HAPE) grows with the increases in pulmonary arterial pressure. HAPE is characterized by severe pulmonary hypertension, though the incidence and relevance of individual risk factors are not yet predictable. However, the systolic pulmonary pressure (SPAP) and peak in tricuspid regurgitation velocity (TVR) are crucial factors when diagnosing pulmonary hypertension by echocardiography. Methods: The SPAP and TVR of 27 trekkers aged 20-65 years en route in the Solu Khumbu region of Nepal was assessed. Echocardiograph measurements were performed at Lukla (2,860 m), Gorak Shep (5170 m), and the summit of Kala Patthar (5,675 m). The altitude profile and the participant’s characteristics were also compiled for correlation with the measured data. Results: The results showed a highly significant increase of SPAP and TVR after ascending Kala Patthar. The study revealed a lower increase of SPAP and TVR in the group of older participants, although the initial respective measurements in Gorak Shep were significantly higher for this group. A similar finding occurred in those using Diamox® as prophylaxis. There was an inverse relationship between TVR and SPAP, the peripheral capillary oxygen saturation and heart rate. Conclusions: The echocardiograph results indicate that older people are a risk group for developing a HAPE. The prophylactic use of acetazolamid led to higher initial SPAP values in Gorak Shep, and a lower increase of SPAP as well as TRV after ascending Kala Patthar. Arterial oxygen saturation measurements can provide an indicator for the self-assessment for the risk of developing HAPE and provide a rule of thumb for the altitude profile but does not replace a HAPE diagnosis. The collected data variables concerning backpack weight, sex, workload (actual ascent speed), and pre-existing diseases were not statistically significant factors related to SPAP and TVR (p=<0.05).

Preprint ARTICLE | doi:10.20944/preprints202207.0151.v1

Psychological Distress in South African Healthcare Workers early in the COVID-19 Pandemic: An Analysis of Associations and Mitigating Factors

Hsin-Ling Lee, Kerry Wilson, Colleen Bernstein, Nisha Naicker, Annalee Yassi

Subject: Medicine And Pharmacology, Psychiatry And Mental Health Keywords: psychological distress; COVID-19 pandemic; health care workers; perceived risks; workplace relationship; support; training; workplace hazards; perceived barriers; job tension

Online: 11 July 2022 (07:40:12 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202204.0217.v1

Factors Associated with the Prevalence of Malnutrition among Adult Haemodialytic Patients: A Two-Centre Study in Jeddah Region, Saudi Arabia

Firas S. Azzeh, Waad M. Turkistani, Mazen M. Ghaith, Lujain A. Bahubaish, Osama A. Kensara, Hussain A. Almasmoum, Abdullah F. Aldairi, Anmar A. Khan, Ahmad A. Alghamdi, Ghalia Shamlan, Maha H. Alhussain, Reham M. Algheshairy, Abdullah M. AlShahrani, Maysoun S. Qutob, Awfa Y. Alazzeh, Haitham M. Qutob

Subject: Medicine And Pharmacology, Dietetics And Nutrition Keywords: Chronic Kidney Disease; Protein-Energy Wasting; Modified-Subjective Global Assessment

Online: 25 April 2022 (04:53:13 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202202.0097.v1

Predictors of Adrenal and Gonadal Hormones in Relation to Biological and Management Factors Among Captive Red Pandas in Indian Zoos

Aamer Sohel Khan, Janine Brown, Vinod Kumar, Govindswamy Umapathy, Nagarajan Baskaran

Subject: Biology And Life Sciences, Endocrinology And Metabolism Keywords: Captive breeding; endangered; red panda; reproductive hormone; stress hormone; welfare

Online: 7 February 2022 (16:07:29 CET)

Show abstract| Download PDF| Supplementary Files| Share

Animals in human care are affected by stressors that can ultimately reduce fitness. When reproduction is affected, endangered species’ conservation programmes can be severely compromised. Thus, understanding factors related to stress and reproduction, and measures of related hormones, are important to ensure captive breeding success. Red pandas are endangered and populations in the wild are threatened with extinction. A global captive breeding programme has been launched to conserve the species with the goal of reintroduction. However there is little informaiton on how stressors impact reproductive aspects of the species. This study measured fecal glucocorticoid (fGCM), fecal progestagen (fPM) and fecal androgen (fAM) metabolite concentrations in 12 female and 8 male red pandas (Ailurus fulgens fulgens) at three zoos in northeastern India to determine predictors of adrenal and gonadal steroid activity and the influence of fGCM on reproduction. Results indicated that fGCM concentrations were higher in males than females, and positively correlated with number of visitors, while negatively related to frequency of feedings and enclosure area. Sex, visitor number, frequency of feeding, and enclosure area explained 67% of the variations in fGCM concentrations in the study population. Concentrations of fPM were positively associated with tree density in the enclosure, explaining 47% of the variation among females. For fAM, positive associations were found with frequency of feeding, but concentrations were negatively related to age and number of visitors; these three covariates explained 45% of the variation in fAM concentration among males. Comparison of fGCM with fPM showed a negative trend, indicating increasing adrenal hormones may decrease reproductive function among female red pandas. The study thus suggests that zoo management should consider increasing feeding frequency, providing larger enclosures with more trees, and regulating visitor numbers to reduce stress and increase reproductive fitness among red pandas.

Preprint ARTICLE | doi:10.20944/preprints202111.0534.v1

Research on Regional Differences and Influencing Factors of Chinese Industrial Green Technology Innovation Efficiency Based on Dagum Gini Coefficient Decomposition

Liyuan Zhang, Pengzhen Liu, Heather Tarbert, Qingyu Bu

Subject: Social Sciences, Geography, Planning And Development Keywords: Industrial green technology innovation efficiency; Dagum Gini coefficient; spatial econometrics; Regional differences

Online: 29 November 2021 (12:34:49 CET)

Show abstract| Download PDF| Share

Industrial green technology innovation has become an important content in achieving high-quality economic growth and comprehensively practicing the new development concept in the new era. This paper measures the efficiency of industrial green technology innovation and regional differences based on Chinese provincial panel data from 2005 to 2018, using a combination of the super-efficient SBM model for considering undesirable outputs and the Dagum Gini coefficient method, and discusses and analyses the factors influencing of the industrial green technology innovation efficiency by constructing a spatial econometric model. The results show that: firstly, the industrial green technology innovation efficiency in China shows a relatively stable development trend, going through three stages: " stationary period", " recession period " and "growth period ". However, the efficiency gap between different regions is obvious, specifically in the eastern > central > western regions of China, and the industrial green technology efficiency innovation in the central and western regions is lower than the national average. Secondly, regional differences in the efficiency of industrial green technology innovation in China are evident but tend to narrow overall, with the main reason for the overall difference being regional differences. In terms of intra-regional variation, variation within the eastern region is relatively stable, variation within the central region is relatively low and shows an inverted 'U' shaped trend, and variation within the western region is high and shows a fluctuating downward trend. Thirdly, the firm size, government support, openness to the outside world, environmental regulations and education levels contribute to the efficiency of industrial green technology innovation. In addition, the industrial structure hinders the efficiency of industrial green technology innovation, and each influencing factor has different degrees of spatial spillover effects.

Preprint ARTICLE | doi:10.20944/preprints202111.0485.v1

Analysis on Spatio-temporal Characteristics and Influencing Factors of Industrial Green Innovation Efficiency——From the Perspective of Innovation Value Chain

Liyuan Zhang, Pengzhen Liu, Heather Tarbert

Subject: Social Sciences, Geography, Planning And Development Keywords: Industrial green innovation efficiency; Innovation value chain perspective; Super-efficient network SBM model; Spatial Dubin model

Online: 25 November 2021 (16:06:00 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202110.0188.v1

Modifiable Lifestyle Factors and their Relationships with Metabolic Disorders among Adults in Burkina Faso: Findings from the First National Survey

Jeoffray Diendéré, Jean Kaboré, Augustin Nawidimbasba Zeba, William Kofi Bosu, Jérôme Winbetourefa Somé, Franck Garanet, Victor Pingdéwendé Ouédraogo, Abdoul Aziz Savadogo, Athanase Millogo

Subject: Medicine And Pharmacology, Endocrinology And Metabolism Keywords: Modifiable lifestyle factors; Metabolic disorders; Prevalence; Relationships; Burkina Faso

Online: 12 October 2021 (21:02:23 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202110.0142.v1

Multiple Effects of Topographic Factors on Spatio-temporal Variations of Vegetation Patterns in the Three Parallel Rivers Region, Southeast Tibet

Chunya Wang, Jinniu Wang, Niyati Naudiyal, Ning Wu, Xia Cui, Yanqiang Wei, Qingtao Chen

Subject: Environmental And Earth Sciences, Environmental Science Keywords: MODIS NDVI; Vegetation cover; Trend analysis; Sen+Mann-Kendall; Topography; GWR; Qinghai-Tibetan Plateau

Online: 8 October 2021 (13:16:27 CEST)

Show abstract| Download PDF| Share

Topographic factors are recognized as one of the key factors influencing vegetation distribution patterns, and studying the interactions between them can contribute to enhancing our understanding of future vegetation dynamics. We used the Moderate-resolution Imaging Spectroradiometer Normalized Differential Vegetation Index (MODIS NDVI) image dataset (2000-2019), combined with Digital Elevation Model (DEM), and vegetation type data for trend analysis, and explored NDVI variation and its relationship with topographic factors through an integrated geographically-weighted model in the Three Parallel Rivers Region (TPRR) of southeastern Tibetan plateau in the past 20 years. Our results indicated that there was no significant increase of NDVI in the entire basin between 2000-2019, except for the Lancang River basin. In the year 2004, abrupt changes in NDVI were observed across the whole basin and each sub-basin. During 2000-2019, the mean NDVI value of the whole basin increased initially and then decreased with the increasing elevation. However, it changed marginally with changes in slope and aspect. We observed a distinct spatial heterogeneity in vegetation patterns with elevation, with vegetation in the southern regions showing higher NDVI than the north as a whole. Most of the vegetation cover was concentrated in the slope range of 8~35°, with no significant difference in distribution except flat-land. Furthermore, from 2000 to 2019, the vegetation cover in the TPRR showed an improving trend with the changes of various topographic factors, with the largest improvement area (36.10%) in the slightly improved category. The improved region was mainly distributed in the source area of the Jinsha River basin and the southern part of the whole basin. Geographically weighted regression (GWR) analysis showed that elevation was negatively correlated with NDVI trends in most areas, especially in the middle reaches of Nujiang River basin and Jinsha River basin, where the influence of slope and aspect on NDVI change was considerably much smaller than elevation.

Preprint ARTICLE | doi:10.20944/preprints202110.0074.v1

Multiple Effects of Topographic Factors on Spatio-temporal Variations of Vegetation Patterns in the Three Parallel Rivers Region, Southeast Tibet

Chunya Wang, Jinniu Wang, Niyati Naudiyal, Ning Wu, Xia Cui, Yanqiang Wei, Qingtao Chen

Subject: Environmental And Earth Sciences, Geography Keywords: MODIS NDVI; Vegetation cover; Trend analysis; Sen+Mann-Kendall; Topography; GWR; Qinghai-Tibetan Plateau

Online: 5 October 2021 (09:16:14 CEST)

Show abstract| Download PDF| Share

Topographic factors are recognized as one of the key factors influencing vegetation distribution patterns, and studying the interactions between them can contribute to enhancing our understanding of future vegetation dynamics. We used the Moderate-resolution Imaging Spectroradiometer Normalized Differential Vegetation Index (MODIS NDVI) image dataset (2000-2019), combined with Digital Elevation Model (DEM), and vegetation type data for trend analysis, and explored NDVI variation and its relationship with topographic factors through an integrated geographically-weighted model in the Three Parallel Rivers Region (TPRR) of southeastern Tibetan plateau in the past 20 years. Our results indicated that there was no significant increase of NDVI in the entire basin between 2000-2019, except for the Lancang River basin. In the year 2004, abrupt changes in NDVI were observed across the whole basin and each sub-basin. During 2000-2019, the mean NDVI value of the whole basin increased initially and then decreased with the increasing elevation. However, it changed marginally with changes in slope and aspect. We observed a distinct spatial heterogeneity in vegetation patterns with elevation, with vegetation in the southern regions showing higher NDVI than the north as a whole. Most of the vegetation cover was concentrated in the slope range of 8~35°, with no significant difference in distribution except flat-land. Furthermore, from 2000 to 2019, the vegetation cover in the TPRR showed an improving trend with the changes of various topographic factors, with the largest improvement area (36.10%) in the slightly improved category. The improved region was mainly distributed in the source area of the Jinsha River basin and the southern part of the whole basin. Geographically weighted regression (GWR) analysis showed that elevation was negatively correlated with NDVI trends in most areas, especially in the middle reaches of Nujiang River basin and Jinsha River basin, where the influence of slope and aspect on NDVI change was considerably much smaller than elevation.

Preprint ARTICLE | doi:10.20944/preprints202107.0446.v1

Non-Modifiable Risk Factors (Age and Sex), Stroke Types, and Outcomes in Rivers State, Nigeria: A Retrospective Hospital-Based Study

Osborne Ikechuckwu Osuegbu, Foluke Olukemi Adeniji, Golden Chukwuemaka Owhonda, Rogers Bariture Kanee, M Alblihed, Gaber El-Saber Batiha, Eric Osamudiamwen Aigbogun

Subject: Medicine And Pharmacology, Immunology And Allergy Keywords: Age; Sex; Stroke Types; Outcomes; SEM; Tertiary Hospitals; Rivers State

Online: 20 July 2021 (11:45:13 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202105.0582.v1

Prevalence and Associated Factors of Under-Five Mortality in Ethiopia: Further Analysis of Ethiopian Mini Demographic and Health Surveys 2019

girma gilano, Samuel Hailegeberael

Subject: Medicine And Pharmacology, Immunology And Allergy Keywords: under-five; mortality; demographic health survey data; Ethiopia

Online: 24 May 2021 (15:12:13 CEST)

Show abstract| Download PDF| Share

Introduction: Over decades, much have been said and done regarding under-five mortality in Ethiopia. The country has been following the lead of sustainable development goals and UNICEF with its transformation plan targets. However, unless the efforts supported by status assessing studies, it might be difficult for the country to progress. Thus, the current study was directed to identify the prevalence and associated factors of under-five mortality in 2019. Methods: According to the study criteria, we extract and cleaned data in STATA v. 15.0. The data then weighted as per the sampling weight, primary sampling unit, and strata before analyzing in STATA 15.0. Data management consisted of descriptive (mean, standard deviation, and proportion or percent) and association statistics. We deliberated binary logistic regression for this analysis and we checked each variable at 0.25 p-values to include in the model. The final p-value to declare association was p <0.05 and AOR with 95% CI was also applied to describe the results. The data source was the Ethiopian Mini Demographic Health Survey (EMDHS) 2019. EMDHS collected the data from 8,885 in a face-to-face manner with a 99% response rate. Results: From 5,527 numbers of weighted women with under-five analysed in this study, the proportion of under-five mortality was 277.23(5.02%). Factors like 2nd birth order 0.52(0.35, 0.79), 3rd-4th 0.49(0.28, 0.84), 1-2 ANC visits 0.24(0.12, 0.49, ANC visit three’ 0.14(0.07, 0.28), ANC visit four and above 0.22(0.14, 0.36), in marriage mother 0.43(0.19, 0.96), ‘1-2 under-five children 0.02(0.011, 0.03), and greater than three under-five children 0.007(0.0007, 0.004) were all negatively associated with under-five mortality rate. Conclusion: To obtain the exalted outcome out of this study, the government might need to increase antenatal care, women education, institutional delivery, and the modern contraceptive methods use through enhanced community mobilization, health education using community health workers, increasing access to essential cares of mothers and children, and the policy commitment for the issues related to family size, birth order, and birth interval.

Preprint ARTICLE | doi:10.20944/preprints202104.0211.v1

Emerging Industry: Identifying the Effective Institutional Factors on the Exploitation of Entrepreneurial Opportunities of Sports Tourism Industry in Developing Countries

Reza Heydari, Mohammad Keshtidar, Haywantee Ramkissoon, Mahdi Esfahani, Ehsan Asadollahi

Subject: Business, Economics And Management, Accounting And Taxation Keywords: Tourism industry; sports tourism; entrepreneurship; institutional factors; development

Online: 7 April 2021 (15:28:25 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202012.0759.v1

The Prevalence of Insulin Resistance and the Associated Risk Factors in a Sample of 14–18-Year-Old Slovak Adolescents

Jana Jurkovicova, Katarina Hirosova, Diana Vondrova, Martin Samohyl, Zuzana Stefanikova, Alexandra Filova, Ivana Kachutova, Jana Babjakova, Lubica Argalasova

Subject: Medicine And Pharmacology, Dietetics And Nutrition Keywords: adolescents; cardiometabolic risk factors; insulin resistance; abdominal obesity; lifestyle; nutritional habits

Online: 30 December 2020 (15:16:17 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202011.0148.v1

Risk Factors for Depression Among Returnee Migrants and Non-migrants Working Adults in Nepal: A Cross-Sectional Community Based Study

Pratik Adhikary, Hridaya Raj Devkota, Arthur L. Reingold, Dirgha J. Ghimire

Subject: Medicine And Pharmacology, Immunology And Allergy Keywords: mental health; working population; labour; migration; depression

Online: 3 November 2020 (13:52:38 CET)

Show abstract| Download PDF| Share

Preprint BRIEF REPORT | doi:10.20944/preprints202009.0711.v1

Prevalence and Associated Factors of Hand and Oral Hygiene Behaviour among Adolescents in Dominican Republic, Suriname and Trinidad and Tobago

Supa Pengpid, Karl Peltzer

Subject: Social Sciences, Psychology Keywords: oral hygiene; hand hygiene; adolescents; Caribbean

Online: 29 September 2020 (12:49:06 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202009.0430.v1

Determination of Risk Factors Associated With Walking Disorders After Anterior Cruciate Ligament Surgery With Hamstring Graft : A Controlled Multicenter Study

Marine Gaignon, Jean Mazeas, Maude Traullé, Amaury Vandebrouck, Pascal Duffiet, Louis Ratte, Florian Forelli

Subject: Medicine And Pharmacology, Orthopedics And Sports Medicine Keywords: anterior cruciate ligament; gait disorder; gait analysis; risk factors

Online: 18 September 2020 (11:17:01 CEST)

Show abstract| Download PDF| Share

Today, rupture of the anterior cruciate ligament is the most common heavy injury in athletes, but it can also occur in sedentary subjects. Its treatment, always adapted to the lifestyle, age and will of the patient, often remains surgical. However, despite its frequency and universality, there are still walking disorders following the operation. These disorders sometimes persist for several months, or even several years after surgery. The present study is therefore interested in determining the risk factors linked to walking disorders following reconstruction of the anterior cruciate ligament. The objective of this study is to determine what risk factors associated with walking disorders are after reconstruction of the anterior cruciate ligament by hamstring graft. This study focused on factors that may exist at 3 and 6 months postoperatively. Two populations participated in this study, a healthy population and a population having benefited from reconstruction of the anterior cruciate ligament. The operated test group is divided into two subgroups, one with a postoperative period of 3 months and the second at 6 months. All subjects were subjected to the same protocol, their gait on the treadmill was analyzed and evaluated with an Optogait® analysis system. A univariate analysis was carried out first. Then, a multivariate analysis by adjustment method was carried out in order to eliminate the potential confounding factors. The comparison of the results between the populations in the univariate analysis shows an absence of significant results however there are trends. The statistical results of the multivariate analysis showed interactions in the two subgroups of the operated population.In fact, it turns out that at 3 months there is a tendency to worse gait disorders in subjects with a high BMI reflecting overweight, when an associated surgical procedure has taken place on the meniscus, in subjects over 35 years of age and males. On the other hand, at 6 months, the tendency to worsening is visible only in the strata represented by subjects with a BMI corresponding to overweight, as well as in subjects having benefited from a meniscal suture associated with ACL reconstruction. .The results of the present study show that there are certain factors which tend to increase the risk of these walking disorders after reconstruction of the anterior cruciate ligament by hamstring graft, these factors are different depending on the time postoperative.

Preprint ARTICLE | doi:10.20944/preprints202007.0679.v1

Prevalence of Sub-clinical Mastitis and Associated Risk Factors at Cow Level in Dairy Farms in Southwestern Part of Bangladesh

Md. Abu Sayeed, Md. Ashikur Rahman, Md. Saiful Bari, Ariful Islam, Md. Mizanur Rahman, Md. Ahasanul Hoque

Subject: Biology And Life Sciences, Animal Science, Veterinary Science And Zoology Keywords: Sub Clinical Mastitis; prevalence; Surf Field Mastitis Test; Jhenaidah

Online: 28 July 2020 (10:40:34 CEST)

Show abstract| Download PDF| Supplementary Files| Share

Preprint REVIEW | doi:10.20944/preprints202006.0120.v1

Why Children Are Less Affected by COVID-19 Than Adults: Potential Immunological Factors and the Renin-Angiotensin System Associated Mechanisms

Olga Krogh-Jensen, Irina Nikitina, Andrew Donnikov, Anna Lenyushkina, Nataliya Degtyareva, Anna Degtyareva

Subject: Medicine And Pharmacology, Epidemiology And Infectious Diseases Keywords: SARS-CoV-2; COVID-19; pathogenesis; children; neonates; immune response; secondary hemophagocytic lymphohistiocytosis; renin-angiotensin system; genetic polymorphisms; ACE2; AGTR2; AGTR1; NOS; lung injury

Online: 9 June 2020 (08:07:40 CEST)

Show abstract| Download PDF| Share

The spread of the infection caused by the new coronavirus SARS-CoV-2 (COVID-19) became pandemic on March 11, 2020. From the time of the first cases (in November 2019, Wuhan, China), to date, a large number of COVID-19 observations have been accumulated in different age groups of patients both in China and abroad. Published scientific data allows us to conclude that children suffer from COVID-19 much less often than adults and tolerate the disease in a milder form, often appear to be asymptomatic. There is currently no final answer why children are less susceptible to this virus; however, scientists are increasingly inclined to consider a complex effect of the immune response and components of the renin-angiotensin system (RAS), which according to recent studies affects not only the cardiovascular system, but is also responsible for the activation of inflammatory reactions. A hypothesis of genetic predisposition to the development of severe forms of COVID-19 has recently been made. We conducted a search for publications in the databases and showed current scientific ideas about COVID-19 pathogenesis and factors influencing the disease development in childhood. Childhood immunity may have several protective features against SARS-CoV-2: immaturity of particular elements of the innate immune response, constitutional lymphocytosis with a shift towards anti-inflammatory Th2-response, as well as "trained" immunity. The influence of renin-angiotensin system reactions in this review is shown from two perspectives: expression of ACE2 receptors and polymorphisms of certain genes of this system. It was established that ACE2 transmembrane protein is not only the entry point for the virus but also plays a regulatory role, turning the pro-inflammatory vasoconstrictor angiotensin II into anti-inflammatory angiotensin (1-7), which has vasodilating properties. Higher ACE2 content in children compared with adults helps maintain balance in the renin-angiotensin system and prevents the development of complications. It was also shown that the presence of certain genetic polymorphisms (AGTR1, AGTR2, ACE2, ACE) could determine the imbalance inside the RAS, leading to more pronounced reactions of alveolocytes, vascular endothelium and smooth muscle fibers in response to SARS-CoV-2 infection due to a shift towards vasoconstrictor, proliferative and profibrotic mechanisms.

Preprint ARTICLE | doi:10.20944/preprints201911.0362.v1

Extending the Models of Employee Turnover to Include External Drivers such as Client-related Factors: A Multi-country, Qualitative Assessment

Katrina Radford, Amber L. Stephenson

Subject: Business, Economics And Management, Human Resources And Organizations Keywords: employee retention; employee turnover; client embeddedness; human resource management

Online: 28 November 2019 (11:22:28 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints201910.0063.v1

Factors Affecting Bulblet Growth of Lilium sp. – A Timeline for Bulblet to Bulb Production Via in Vitro vs Conventional Pathway

Md. Saiful Islam, Kazuhiko Shimasaki

Subject: Biology And Life Sciences, Plant Sciences Keywords: lilium sp.; in vitro protocol; conventional pathway; bulb production; timeline

Online: 7 October 2019 (11:16:43 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints201908.0151.v1

Analysis of Factors Giving the Opportunity for Implementation of Innovations on the Example of Manufacturing Enterprises in the Silesian Province

Henryk Wojtaszek, Ireneusz Miciuła

Subject: Business, Economics And Management, Business And Management Keywords: innovation; innovative activities; analysis of factors; production enterprises

Online: 13 August 2019 (07:34:13 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints201908.0089.v1

On the Key Factors in Higher Education Classroom Design: Physical Aspects of the Undergraduate Teaching and Learning Experience in Malaysia

Laura De Pretto, Ching Lik Hii, Choon Lai Chiang, Sze Pheng Ong, Darlene Elizabeth Sin Yi Tan, Cheng Heng Pang

Subject: Social Sciences, Education Keywords: classroom design; higher education; Malaysia; undergraduate

Online: 7 August 2019 (05:56:20 CEST)

Show abstract| Download PDF| Share

The design, facilities and conditions inside a classroom play a significant role in the teaching and learning experience for both students and lecturers. Prior studies of primary schoolchildren indicate three design principles affecting student learning, namely: naturalness, individualisation and stimulation. The current study extends these investigations to Higher Education through a survey of undergraduate students and university lecturers aimed at determining the most critical factors in undergraduate classroom design. One-to-one interviews were conducted with students and lecturers (n. 31) at the University of Nottingham, Malaysia Campus. Interviewees were encouraged to express their opinions, comments, concerns and suggestions through open-ended questions. The interviews were recorded and then transcribed and coded using NVivo10. Results show a strong desire among lecturers and students for improved classroom equipment, greater flexibility in classroom arrangement, more attractive decoration and for the addition of natural elements to the classroom environment. Of the three design principles, individualisation and naturalness emerged most strongly from the interviews and appear to be more important factors for undergraduates than stimulation. These findings could make a novel and significant contribution to the physical aspects of classroom design in Higher Education settings. Educational institutions are increasingly employing non-traditional classroom designs, which are expected to provide for more flexible, collaborative, and active learning and teaching experiences. Taking into consideration the environmental psychology of teaching and learning, several of the reported design attributes can serve as benchmarks for upgrading current classroom design and facilities in the future, as institutions look to upgrade their physical infrastructures to meet the changing demands of teachers and learners arising from technological innovations and shifts in our understanding of the methods and purposes of Higher Education.

Preprint ARTICLE | doi:10.20944/preprints201906.0023.v1

A Robust Vision-based Method for Displacement Measurement under Adverse Environmental Factors using Spatio-Temporal Context Learning and Taylor Approximation

Chuan-zhi Dong, Ozan Celik, Fikret Catbas, Eugene OBrien, Su Taylor

Subject: Engineering, Civil Engineering Keywords: structural health monitoring; displacement measurement; non-contact; computer vision, environmental factors; spatio-temporal context; Taylor approximatio

Online: 3 June 2019 (12:59:00 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints201806.0129.v1

In Search of Factors Negatively Affecting Vaccine Immunity to Pertussis in Preschool Children Before the Administration of the First Booster

Anna Bednarek, Anna Bodajko-Grochowska, Barbara Hasiec, Robert Klepacz, Katarzyna Szczekala, Danuta Zarzycka, Andrzej Emeryk

Subject: Medicine And Pharmacology, Pediatrics, Perinatology And Child Health Keywords: negatively factors; pertussis; preschool children; vaccine immunity

Online: 8 June 2018 (11:28:56 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints201805.0361.v1

Socio-Economic Factors Influencing Use and Adoption of Family-Sized Bio-digesters as Renewable Energy Sources in Ngoma District, Rwanda

Danson Musinguzi, Emmanuel Kayinamura, Anne Tumushabe, Daniel Omuna, Emmaniel Innocent Eniru, Oluwole Olusegun Akiyode, Hadijjah Katongole, Edson Mwebesa, Twaha Ali Basamba, Dominic Byarugaba

Subject: Engineering, Energy And Fuel Technology Keywords: bio-digesters; household income levels; renewable energy; socio-economic

Online: 25 May 2018 (10:55:58 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints201801.0201.v1

Risk Factors of Extended-Spectrum β-Lactamase Producing Enterobacteriaceae Occurrence in Farms in Reunion, Madagascar and Mayotte Islands, 2016–2017

Noellie Gay, Alexandre Leclaire, Morgane Laval, Guillaume Miltgen, Mael Jego, Stéphane Ramin, Julien Jaubert, Olivier Belmonte, Eric Cardinale

Subject: Biology And Life Sciences, Animal Science, Veterinary Science And Zoology Keywords: Indian ocean; livestock; Extended-Spectrum β-Lactamase producing Enterobacteriaceae; risk factors; CTX-M; enzymes

Online: 22 January 2018 (12:02:53 CET)

Show abstract| Download PDF| Supplementary Files| Share

Preprint ARTICLE | doi:10.20944/preprints202409.1855.v1

Antimicrobial Susceptibility of Uropathogenic Escherichia coli with Analysis of Impact of Socio-Economic Factors in Low, Medium and High-Income Countries

Meher Rizvi, Maria Khan, Amina AL Jardani, Ujjala Ghoshal, Zaaima AL Jabri, Mohammad Ahanjan, Azza AL Mamari, Nawal AL Shizawi, Hiba Sami, Abdullah Balkhair, Adila Shaukat, Alwarith Nasser Salem Alkharusi, Abdulrahman Almahrouqi, Afreenish Hassan, Ajay Kumar, Amal Malehi, Amina Gul, Ashima Singh, Asma Said Hamed AL Shidhani, Areena Hoda Siddiqui, Aruna Poojary, Azza AL Rashdi, Bradley Langford, Dmytro Stepanskyi, Abbas Dolatabadi, Aisha Al Mufraji AL Mufraji, Elham Said Ahmed AL Risi, Garima Kapoor, Isabella Princess, Hatim Ali Eltahir, Hilal Al Sidairi, Kaitlyn Dougherty, Katia Iskandar, Ken Masters, Ibrahim Khalaf Hamdan AL Busaidi, Laila AL Yazidi, Mahfuza Nasrin, Mahmood Salim AL Subhi, Mallika Sengupta Mallika Sengupta, Manisha Khandait, Nada Khalfan AL Tamtami, Nada Khafan Alsiyabi, Nawal AL Kindi, Nazla Musthafa Luthfee, Neha Shreshtha, Nihal Mohamed Amur AL Riyami, Noora Hilal Ali AL Busaidi, Nupur Goel, Oksana Ishchenko, Omnia Mohamed Elnabawy Ahmed Taher, Pragnya Paramita Jena, Rajni Ekadashi, Razan Zadjali, Reba Kanungo, Sara Abolghasemi, Salima Al-maqbali, Sanjay Jaju, Sayantan Banerjee, Shadma Yaqoob, Shahnaz Sali, Shafqat Husnain Khan, Shalini Malhotra, Stephen Hughes, Sundas Shaukat, Syed Mohammed Atif, Vrushali Vishwas Patwardhan, Victorien Dougnon, Wahid Khan, Walid Wali, Zakariya AL Muharrmi, Zeeshana Basit, Jasashree Choudhury, Rachita Pravalina, Sanjeev Singh, Sarman Singh, Neelam Taneja, Raman Sardana, Pawan Kapoor, Rajeev Soman, Rashid Al Abri

Subject: Medicine And Pharmacology, Epidemiology And Infectious Diseases Keywords: community acquired UTI; Escherichia coli; antimicrobial susceptibility; Indian subcontinent; MENA; GDP; temperature

Online: 24 September 2024 (12:32:05 CEST)

Show abstract| Download PDF| Supplementary Files| Share

Preprint ARTICLE | doi:10.20944/preprints202409.1253.v1

Distribution Characteristics of Trichiurus japonicus and Its Relationship with Environmental Factors in Central and Southern East China Sea and Yellow Sea

Xinyu Shi, Zhanhu Lu, Zhongming Wang, Jianxiong Li, Xin Gao, Zhuang Kong, Wenbin Zhu

Subject: Physical Sciences, Other Keywords: East China Sea; south central Yellow Sea; Trichiurus japonicus; Species distribution model; Spatial distribution; Environmental factor

Online: 17 September 2024 (02:55:51 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202409.0705.v1

Importance-Performance Analysis of Factors Affecting the Sustainability and Development of Poultry Farms (Evidence from Broiler Farms in Baghlan Province, Afghanistan)

Muhammad Asef Shaiq, Moienuddin Naiemi, Khalil Razavi, Shir Agha Asim Hamidi

Subject: Business, Economics And Management, Business And Management Keywords: Poultry farming; Importance -performance; Baghlan; Afghanistan

Online: 10 September 2024 (13:04:07 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202408.1151.v1

“It Is My Responsibility to Escort My Child to School …” Factors Influencing Parental Involvement in Educating Children with Disabilities in Malawi

David John Musendo, Maria Zuurmond, Thomas Nkhonjera, Sarah Polack, Daksha Patel

Subject: Social Sciences, Education Keywords: parent or family involvement; children with disabilities; school; parent‐teacher relationships; education; COM‐B model

Online: 15 August 2024 (12:25:10 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202407.2112.v1

Sociodemographic Factors Related to Perceived Physical Activity on Chilean Adults: Consequences of Post-pandemic COVID-19 Movement Habits and Sedentary Lifestyle

Rodrigo Gallardo-Rodríguez, Felipe Poblete-Valderrama, Viviana Rodas-Kürten, J. Paulo Vilas-Boas

Subject: Public Health And Healthcare, Physical Therapy, Sports Therapy And Rehabilitation Keywords: physical activity; sedentarism; COVID-19; sociodemographic

Online: 26 July 2024 (09:10:57 CEST)

Show abstract| Download PDF| Share

Preprint REVIEW | doi:10.20944/preprints202407.1231.v1

Deciphering the Complexities of Acute Myeloid Leukemia: Emerging Roles of Epithelial to Mesenchymal Transition Transcription Factors (EMT-TFs) in Disease Progression

Diego Cuevas, Roberto Amigo, Adolfo Agurto, Adan Andreu Heredia, Catherine Guzmán, Antonia Recabal-Beyer, Valentina González-Pecchi, Teresa Caprile, Jody J. Haigh, Carlos Farkas

Subject: Biology And Life Sciences, Other Keywords: AML Classification; MLL-AF9 Fusion; Hematopoietic Stem Cells; Epithelial-Mesenchymal Transition (EMT); Genetic Aberrations in AML; Therapy-Resistant AML; Extramedullary Engraftment

Online: 15 July 2024 (16:25:10 CEST)

Show abstract| Download PDF| Share

Search Results

71240 articles found