ARTICLE
|
doi:10.20944/preprints202308.0796.v1
Subject:
Biology And Life Sciences,
Neuroscience And Neurology
Keywords:
anesthesia neurotoxicity; neuropathic pain; neural activity; mammalian target of rapamycin (mTOR); dorsal spinal cord (DSC), dorsal root ganglion (DRG).
Online: 10 August 2023 (08:17:30 CEST)
ARTICLE
|
doi:10.20944/preprints202306.0660.v1
Subject:
Engineering,
Chemical Engineering
Keywords:
Electrochemical Promotion of Catalysis (EPOC); non-Faradaic electrochemical modification of catalytic activity (NEMCA); CO2 Hydrogenation; Rh; Rhodium; YSZ; XPS
Online: 9 June 2023 (03:50:24 CEST)
ARTICLE
|
doi:10.20944/preprints202302.0017.v1
Subject:
Social Sciences,
Psychology
Keywords:
Digital Mental Health; deprivation; service activity; Mental health concerns; ethnicity; time-series analysis; Covid-19; Text-based online therapy
Online: 2 February 2023 (01:30:05 CET)
ARTICLE
|
doi:10.20944/preprints202212.0410.v1
Subject:
Medicine And Pharmacology,
Clinical Medicine
Keywords:
Heart rate variability; COVID-19; post-COVID-19 condition; long COVID; autonomic dysfunction; vagal nerve activity; symptomatology; lung function
Online: 22 December 2022 (03:13:53 CET)
ARTICLE
|
doi:10.20944/preprints202210.0380.v1
Subject:
Chemistry And Materials Science,
Organic Chemistry
Keywords:
sulfo-derivatives of azoles; alkaloid cytisine; spatial structure; hemorheological activity; 1H; 13C; 2D NMR spectroscopy; X-ray diffraction analysis
Online: 25 October 2022 (07:33:55 CEST)
ARTICLE
|
doi:10.20944/preprints202208.0511.v1
Subject:
Biology And Life Sciences,
Plant Sciences
Keywords:
Zingiber cassumunar Roxb.; essential oils; microencapsulated products; antibacterial activity; agricultural pathogens; foodborne pathogens; gram-positive bacteria; gram-negative bacteria
Online: 30 August 2022 (07:02:54 CEST)
ARTICLE
|
doi:10.20944/preprints202106.0245.v1
Subject:
Chemistry And Materials Science,
Analytical Chemistry
Keywords:
extract of humic substances; fulvic acid; standardization; nanoparticles of polyelectrolytes; antiviral activity; SARS-CoV-2; VERO-E6; Spirotox-method
Online: 9 June 2021 (07:42:16 CEST)
ARTICLE
|
doi:10.20944/preprints202102.0422.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
Hemocytes; Innate Immune Cells; Phagocytic Activity; Respiratory Burst; White-Shrimp; Microalgae; Immunomodulator; Toxicity; Extracellular Polysaccharide; Vibrio harveyi; Danio rerio
Online: 18 February 2021 (15:56:44 CET)
ARTICLE
|
doi:10.20944/preprints202407.2085.v1
Subject:
Chemistry And Materials Science,
Food Chemistry
Keywords:
Shading nets; blackberries; raspberries; phenolic compounds; anthocyanins; cyanidin-3-O-glucoside; cyanidin-3-O-sophoroside; HPLC-DAD; antioxidant activity; DPPH
Online: 25 July 2024 (14:51:43 CEST)
ARTICLE
|
doi:10.20944/preprints202405.1470.v1
Subject:
Chemistry And Materials Science,
Organic Chemistry
Keywords:
tuberculosis; sulfonyl hydrazones; acute toxicity; sub-acute toxicity; antioxidant activity; Mycobacterium tuberculosis; enoyl-ACP reductase; Single crystal x-ray diffraction
Online: 23 May 2024 (10:01:34 CEST)
ARTICLE
|
doi:10.20944/preprints202403.0693.v1
Subject:
Biology And Life Sciences,
Cell And Developmental Biology
Keywords:
miR-1; epigenetic regulator; cardiac sinoatrial region; molecular mechanisms; HDAC4; Calmodulin; pErk2/MAPK1; Mef2c activity; retinoic acid signaling; cardiac development
Online: 12 March 2024 (10:22:13 CET)
COMMUNICATION
|
doi:10.20944/preprints202312.0554.v1
Subject:
Computer Science And Mathematics,
Artificial Intelligence And Machine Learning
Keywords:
automated troubleshooting; real-time product activity detection; problem root cause analysis; machine learning; explainable AI; proactive SaaS support
Online: 8 December 2023 (04:34:50 CET)
ARTICLE
|
doi:10.20944/preprints202310.0688.v1
Subject:
Biology And Life Sciences,
Biology And Biotechnology
Keywords:
antimicrobial activity; Bacillus subtilis; Bacillus thuringiensis; Bacillus toyonensis; Bacillus acidiproducens; Bacillus cereus; Bacillus safensis; GC–MC analysis, volatile organic compounds.
Online: 11 October 2023 (07:38:12 CEST)
ARTICLE
|
doi:10.20944/preprints202309.0911.v1
Subject:
Chemistry And Materials Science,
Materials Science And Technology
Keywords:
hydrogel sodium alginate; active coating gel; thymol; halloysite nanotubes; hydrogels; gels; barrier properties; antioxidant activity; “tsalafouti” soft cheese preservation process;
Online: 13 September 2023 (14:15:49 CEST)
ARTICLE
|
doi:10.20944/preprints202308.1493.v1
Subject:
Medicine And Pharmacology,
Pharmacy
Keywords:
silver nanoparticles; chlorhexidine; conjunction; complexation; surface functionalization; nano-scaled drug delivery; antimicrobial synergism; antiviral activity; Camellia sinensis catechins; green synthesis
Online: 22 August 2023 (09:52:09 CEST)
ARTICLE
|
doi:10.20944/preprints202305.1086.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
antimicrobial activity; Cymbopogon citratus; Cyperus scariosus; GC/MS; headspace analysis; macrodilution; MTT assay; respiratory infections; Trachyspermum ammi; vapor phase; volatiles
Online: 16 May 2023 (04:56:04 CEST)
ARTICLE
|
doi:10.20944/preprints202301.0376.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
sulphur amino acids; anticancer activity; metastasis; cancer metabolism; colorectal cancer; ovari-an cancer; renal cancer; methionine; cysteine; taurine; amino acids
Online: 22 January 2023 (04:09:19 CET)
ARTICLE
Subject:
Chemistry And Materials Science,
Food Chemistry
Keywords:
pomegranate tannins; ellagic acid; molecular modelling; α2-adrenoreceptors; α2-ARs; molecular dynamic simulations; antioxidant; natural compounds; antidepressant activity; food chemistry
Online: 1 October 2021 (14:27:20 CEST)
ARTICLE
|
doi:10.20944/preprints202101.0478.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
ocular drug delivery system; topical liposomes; posterior segment of the eye; safety and toler-ability; biologic activity; diabetic macular edema
Online: 25 January 2021 (10:48:51 CET)
ARTICLE
|
doi:10.20944/preprints202011.0363.v1
Subject:
Chemistry And Materials Science,
Analytical Chemistry
Keywords:
cannabinoid receptor 1; synthetic cannabinoids; quantitative structure-activity relationship; multiple linear regression; partial least squares regression; dependence and abuse potential
Online: 13 November 2020 (07:19:36 CET)
ARTICLE
|
doi:10.20944/preprints202002.0345.v1
Subject:
Chemistry And Materials Science,
Electrochemistry
Keywords:
platinum electrocatalys; PtCu/C; oxygen electroreduction; methanol electrooxidation; catalyst activity; durability; fuel cell life tests; de-alloyed catalysts; PEM FC
Online: 24 February 2020 (03:56:11 CET)
ARTICLE
|
doi:10.20944/preprints202001.0182.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
dinoflagellate; Karenia mikimotoi; glycolipids; monogalactosyldiacylglycerol; monogalactosylmonoacylglycerol; polyunsaturated fatty acid methyl ester; Staphylococcus aureus; Escherichia coli; Candida albicans; anti-inflammatory activity
Online: 17 January 2020 (09:18:08 CET)
ARTICLE
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
DNA lesions; 7,8-dihydro-8-oxoguanine (8-oxoG); mutagenic activity; method of detection; cell nuclear extracts; mice organs and embryos
Online: 14 November 2019 (09:00:19 CET)
REVIEW
|
doi:10.20944/preprints201905.0338.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
castor bean; cancer therapy; immunotoxins; plant toxins; ribosome-inactivating proteins; ricin; rRNA N-glycosylase activity; traditional medicine; folk medicine; bioterrorism.
Online: 28 May 2019 (11:54:43 CEST)
ARTICLE
Subject:
Medicine And Pharmacology,
Psychiatry And Mental Health
Keywords:
physical activity; depression; elderly people living alone; Patient Health Questionnaire-10; flexibility exercise; muscular strength exercise; complex sample logistic regression
Online: 25 March 2019 (11:10:17 CET)
ARTICLE
|
doi:10.20944/preprints201810.0586.v1
Subject:
Computer Science And Mathematics,
Robotics
Keywords:
human activity recognition; gait analysis; human gait inference; wearable sensors; limb amputation; lower limbic prosthesis; machine learning; recurrent neural networks
Online: 25 October 2018 (04:51:27 CEST)
ARTICLE
|
doi:10.20944/preprints201704.0154.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
water bridging; dipole waves; coherent states; polymerase chain reaction; DNA amplification; DNA transduction; enzyme catalytic activity; fractal-like self-similarity
Online: 25 April 2017 (04:24:21 CEST)
ARTICLE
|
doi:10.20944/preprints202406.0303.v1
Subject:
Chemistry And Materials Science,
Materials Science And Technology
Keywords:
N-vinylpyrrolidone; acrylic acid; triethylene glycol dimethacrylate; radical terpolymerization; amphiphilic terpolymers; functional compound; methylphemophide a; biological activity; cell accumulation; medicinal chemistry
Online: 5 June 2024 (15:22:37 CEST)
ARTICLE
|
doi:10.20944/preprints202401.1029.v1
Subject:
Medicine And Pharmacology,
Cardiac And Cardiovascular Systems
Keywords:
premature ventricular contractions; right ventricular outflow tract; left ventricular outflow tract; catheter ablation; athletes; leisure-time athletes; agonist athletes; sports activity
Online: 14 January 2024 (15:49:41 CET)
COMMUNICATION
|
doi:10.20944/preprints202312.0651.v2
Subject:
Medicine And Pharmacology,
Hematology
Keywords:
alternative leukemia treatment; antileukemic agents; antimicrobial peptide; dual-activity compounds; bioconjugates; cell penetration peptide; ciprofloxacin; hematopoietic stem cell transplantation; levofloxacin; lactoferricin B; fluconazole; fluoroquinolones.
Online: 29 January 2024 (08:40:14 CET)
ARTICLE
|
doi:10.20944/preprints202309.0875.v1
Subject:
Chemistry And Materials Science,
Analytical Chemistry
Keywords:
nondestructive analysis, ratio spectral index (RSI); normalized difference spectral index (NDSI); difference spectral index (DSI); polyphenols; antioxidation; Aβ aggregation inhibitory activity
Online: 13 September 2023 (10:57:21 CEST)
ARTICLE
|
doi:10.20944/preprints202309.0732.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
2-aminobenzimidazole derivatives; ethyl, phenyl substituents; transition metal complexes; biological activity; non-covalent interactions H...π, lone pair...π, π...π
Online: 12 September 2023 (16:55:46 CEST)
ARTICLE
|
doi:10.20944/preprints202111.0028.v1
Subject:
Medicine And Pharmacology,
Obstetrics And Gynaecology
Keywords:
pregnant mothers, physical activity; maternal wellbeing; antenatal mothers; newborn outcomes; m-health; low birth weight; small for gestation; gestation age; hemoglobin
Online: 1 November 2021 (17:50:14 CET)
REVIEW
|
doi:10.20944/preprints201805.0426.v1
Subject:
Medicine And Pharmacology,
Medicine And Pharmacology
Keywords:
biological activity; crosslinking; drug delivery; cosmetic; food-supplement; functionalization; hyaluronan applications; hyaluronan derivatives; hyaluronan synthases; hyaluronic acid; hyaluronidases; physico-chemical properties
Online: 29 May 2018 (12:13:48 CEST)
ARTICLE
|
doi:10.20944/preprints201705.0132.v1
Subject:
Biology And Life Sciences,
Plant Sciences
Keywords:
Pittosporum tobira (Thunb.) Aiton; Essential oils (EOs); Headspace solid-phase microextraction (HS-SPME); Gas chromatography-mass spectrometry (GC-MS); Anticancer activity
Online: 17 May 2017 (13:08:12 CEST)
REVIEW
|
doi:10.20944/preprints202407.0536.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
SARS-CoV-2 Main Protease/3CLPro; mutations; vaccine efficacy; Enzymatic activity; therapeutic targeting; Structural alterations; Antiviral therapy; Dimerization interface
Online: 8 July 2024 (03:05:05 CEST)
ARTICLE
|
doi:10.20944/preprints202404.0375.v1
Subject:
Computer Science And Mathematics,
Artificial Intelligence And Machine Learning
Keywords:
Multivariate Time Series Classification; Human Motion Recognition; Human Activity Recognition; Medical Signal Classification; Two-stream Model; Depthwise Separable Convolution; Differential LSTM network
Online: 4 April 2024 (12:13:54 CEST)
ARTICLE
|
doi:10.20944/preprints202310.1074.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
mixed-based combinatorial library; structure–activity relationships; cyclic peptide; mu-opioid receptor; delta-opioid receptor; bifunctional ligand; antinociception; opioid antagonist; opioid liabilities
Online: 17 October 2023 (11:21:32 CEST)
ARTICLE
|
doi:10.20944/preprints202306.2141.v1
Subject:
Physical Sciences,
Condensed Matter Physics
Keywords:
membrane technologies; palladium-containing films; surface modification; nanostructured sur-face; pentagonal structured particles; catalytic activity; hydrogen permeability; hydrogen carriers; high-purity hydrogen
Online: 29 June 2023 (13:16:46 CEST)
ARTICLE
|
doi:10.20944/preprints201608.0162.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
bacterial ghosts (BGs); Vibrio parahaemolyticus; chemically induced lysis; minimum inhibition concentration (MIC); sodium hydroxide (NaOH); lipopolysaccharides (LPS); endotoxic activity; macrophages; cytotoxicity; cytokine
Online: 17 August 2016 (10:26:00 CEST)
COMMUNICATION
|
doi:10.20944/preprints202403.1105.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Boehmeria Nivea Extract (BNE-RRC); Epithelial-Mesenchymal Transition (EMT); Mesenchymal-Epithelial Transition (MET); Anchorage-Independent Growth; Telomerase Activity, and Reversal of EMT
Online: 20 March 2024 (04:42:35 CET)
REVIEW
|
doi:10.20944/preprints202401.2227.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
Cytolytic Activity (CYT); Tumor-Infiltrating Lymphocytes (TILs); Gene Expression Profiling; Spatial Analysis Techniques; Immune Checkpoint Pathways; Tumor Microenvironment (TME); Antigen Presentation; Metabolic Pathways
Online: 31 January 2024 (12:32:26 CET)
REVIEW
|
doi:10.20944/preprints202309.1520.v1
Subject:
Medicine And Pharmacology,
Obstetrics And Gynaecology
Keywords:
Stein-Leventhal Syndrome; Polycystic Ovary Syndrome; Sexuality; Sexual Activity; Sexual Dysfunction; Female Sexual Function Index; Sexual Function; Sexual Disorders; Sexual Behavior; Meta-analysis.
Online: 22 September 2023 (09:58:09 CEST)
ARTICLE
|
doi:10.20944/preprints202011.0305.v1
Subject:
Chemistry And Materials Science,
Analytical Chemistry
Keywords:
Leucophyllum frutescens; Total Phenolic Contents (TPC); Total Flavonoid Content (TFC); Total Antioxidant Activity (TAA); DPPH; CUPRAC; FRAP; gas chromatography-mass spectrometry (GC-MS)
Online: 10 November 2020 (12:00:06 CET)
ARTICLE
|
doi:10.20944/preprints201810.0729.v1
Subject:
Chemistry And Materials Science,
Nanotechnology
Keywords:
silver nanoparticles; laser ablation in liquids; laser synthesis of colloidal nanoparticle solution, nanoparticle impregnated paper; antimicrobial activity; fiber fines; sheet forming; vacuum filtration
Online: 30 October 2018 (16:14:31 CET)
REVIEW
|
doi:10.20944/preprints201807.0143.v1
Subject:
Biology And Life Sciences,
Endocrinology And Metabolism
Keywords:
Aromatic hydroxy metabolites; arenolic drug metabolites; metabolic O-dealkylation; metabolic aromatic ring hydroxylation; primary and auxiliary pharmacophores; auxophores; metabolic modification of drug activity
Online: 9 July 2018 (13:28:16 CEST)
ARTICLE
|
doi:10.20944/preprints202403.1156.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Staphylococcus aureus α -toxin; Bacillus cereus hemolysin II; cytotoxin K2; suppression of hemolytic activity; monoclonal antibodies; enzyme immunoassay
Online: 20 March 2024 (12:23:07 CET)
ARTICLE
|
doi:10.20944/preprints202403.1085.v1
Subject:
Biology And Life Sciences,
Agricultural Science And Agronomy
Keywords:
Solanum tuberosum; dry matter; starch; protein; ascorbic acid; carotenoids; anthocyanins; total acidity; reducing sugars; phenolic compounds; antioxidant activity; meteorological conditions of the growing season
Online: 19 March 2024 (10:17:31 CET)
REVIEW
|
doi:10.20944/preprints202308.0434.v1
Subject:
Medicine And Pharmacology,
Medicine And Pharmacology
Keywords:
In silico studies; drug discovery; SARS-CoV-2; molecular docking; virtual screening; molecular dynamics simulations; drug candidates; antiviral activity; receptor-ligand complex; drug design
Online: 4 August 2023 (11:11:21 CEST)
REVIEW
|
doi:10.20944/preprints202305.2152.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
cancer metabolism; anticancer activity; artificial diets; in vivo; mice; essential amino acids; non-essential amino acids; restriction; leucine; methionine; cysteine; arginine; serine; glutamine; asparagine
Online: 30 May 2023 (13:24:11 CEST)
ARTICLE
|
doi:10.20944/preprints202301.0071.v1
Subject:
Physical Sciences,
Astronomy And Astrophysics
Keywords:
Carrington event; craters; cratering; currents in plasma; electric discharge machining; geology; heliophysics; impact craters; Late Heavy Bombardment; piezoelectricity; transient crater; solar activity; Solar System
Online: 4 January 2023 (07:19:46 CET)
ARTICLE
|
doi:10.20944/preprints202111.0018.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
Newcastle Disease Virus (NDV); NDV ZG1999HDS; NDV La Sota; TLT (Human macrophage cell line; Immunomodulation; Anti - Gram Positive bacteria; Anti - Gram - Negative bacteria; activity
Online: 1 November 2021 (13:01:38 CET)
ARTICLE
|
doi:10.20944/preprints202012.0414.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
galantamine; curcumin; in vivo AChE inhibition; acute toxicity in mice; antioxidant activity; malondialdehide levels; glutathione levels; brain homogenate; complete blood count; biochemical serum parameters
Online: 16 December 2020 (13:45:10 CET)
ARTICLE
|
doi:10.20944/preprints201808.0457.v1
Subject:
Engineering,
Bioengineering
Keywords:
Sleep, Office workers, office workstation, wellbeing, stress, physical activity, wearables, digital health, sleep quality index, tracking sleep quality, workstation types, accelerometry, heart rate variability
Online: 27 August 2018 (11:33:23 CEST)
ARTICLE
|
doi:10.20944/preprints202310.0143.v2
Subject:
Public Health And Healthcare,
Physical Therapy, Sports Therapy And Rehabilitation
Keywords:
Adolescents; Physical Activity; Muscle Power; Handgrip Strength; Dynamic Knee Val-28 gus; Screen Time; Movement Behavior; BMI; body mass index; Single Leg Drop Jump Test
Online: 6 October 2023 (08:35:34 CEST)
ARTICLE
|
doi:10.20944/preprints202306.0763.v1
Subject:
Biology And Life Sciences,
Agricultural Science And Agronomy
Keywords:
Mycogone perniciosa; Bacillus subtilis; industrial Bacillus strains; microbiocontrol; antifungal activity; producer strains; biological efficacy; multirecycled spent mushroom substrates; multirecycled SMS aqueous extracts; submerged multibiorecycled biologics
Online: 12 June 2023 (04:56:57 CEST)
ARTICLE
|
doi:10.20944/preprints202008.0056.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
Cornu aspersa mucus; antimicrobial peptides; antibacterial activity; bacterial strains; Pseudomonas aureofaciens AP9; Escherichia coli NBIMCC 8785; Brevibacillus laterosporus strain BT-271; Clostridium perfringens NBIMCC 8615
Online: 3 August 2020 (00:25:22 CEST)
ARTICLE
|
doi:10.20944/preprints202401.0050.v1
Subject:
Environmental And Earth Sciences,
Atmospheric Science And Meteorology
Keywords:
sea surface temperature (SST); El-Nino - Southern Oscillation (ENSO); long-term variability; numerical simulation; reanalysis data; stratospheric ozone; stratosphere polar vortex (SPV); residual circulation; wave activity
Online: 2 January 2024 (07:57:50 CET)
ARTICLE
|
doi:10.20944/preprints201801.0022.v1
Subject:
Chemistry And Materials Science,
Analytical Chemistry
Keywords:
Phaleria macrocarpa; extraction; free radical scavenging activity (DPPH); ferric ion reducing power assay (FRAP); total phenolic content (TPC); total flavonoid content (TFC); response surface methodology (RSM)
Online: 3 January 2018 (10:15:16 CET)
ARTICLE
|
doi:10.20944/preprints201909.0001.v2
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
treating filler complications; hyaluronidase; red king crab; hepatopancreas; hyaluronic acid (HA); hyaluronidase activity; turbidimetric method; atomic force microscopy (AFM); nuclear magnetic resonance (NMR); Revofil Ultra filler; Hyaluform deep filler; Lydase; Liporase
Online: 14 October 2019 (15:42:23 CEST)
REVIEW
|
doi:10.20944/preprints201809.0281.v1
Subject:
Biology And Life Sciences,
Cell And Developmental Biology
Keywords:
axon guidance; growth cone; cytoskeleton; caspases; apoptosis; signal integration; basal level of caspase activity; death associated inhibitor of apoptosis; axon branching; Netrin; DCC; frazzled; slit; robo; Drosophila
Online: 16 September 2018 (09:43:52 CEST)
REVIEW
|
doi:10.20944/preprints202408.1827.v1
Subject:
Computer Science And Mathematics,
Mathematical And Computational Biology
Keywords:
Predictive Toxicology; Omics Technologies; Machine Learning; Structure-Activity Relationship; Fragment-Based Drug Design; Microphysiological Systems; Physiologically Based Pharmacokinetic Modeling; Virtual Screening; Biochemical Targets; Automated De Novo Drug Design
Online: 26 August 2024 (11:31:51 CEST)
BRIEF REPORT
|
doi:10.20944/preprints202106.0341.v2
Subject:
Medicine And Pharmacology,
Medicine And Pharmacology
Keywords:
Impact of COVID on TB; TB Notification in India; Integrated TB COVID Activity; Threats and Opportunity during COVID; Initiatives to improve TB Surveillance; TB Surveillance during COVID Pandemic
Online: 22 June 2021 (14:05:04 CEST)
REVIEW
|
doi:10.20944/preprints202308.1948.v2
Subject:
Physical Sciences,
Astronomy And Astrophysics
Keywords:
Sun: corona; Sun: radio radiation; acceleration of particles; magnetic reconnection; Sun: Radiation mechanisms: non-thermal; Sun: Meter-Wavelengths and Longer; Sun: activity; Sun: Flares; Sun: Ejections; Sun: magnetic fields
Online: 19 September 2023 (03:38:47 CEST)
ARTICLE
|
doi:10.20944/preprints202406.0729.v1
Subject:
Medicine And Pharmacology,
Complementary And Alternative Medicine
Keywords:
hormonal replacement therapy (HRT); mindfulness-based stress reduction (MBSR); Risk reducing salpingo-oophorectomy (RRSO); Breast Cancer Associated Susceptibility Protein Type 1/2 (BRCA1/2) mutations; Menopause rating scale (MRS); menopause/perimenopause/postmenopausal; psychological symptoms; physical activity/exercise; breast cancer
Online: 12 June 2024 (00:04:00 CEST)
REVIEW
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
metabolic functionalization of alkyl moieties in drug molecules; structure influence on metabolic functionalization of alkyl moieties; mechanism of alkyl free radical hydroxy functionalization; pharmacologic activity of hydroxy and carboxy functionalized alkyl moieties in drug molecules; primary and auxiliary pharmacophores; auxophores
Online: 11 March 2020 (03:20:58 CET)
ARTICLE
|
doi:10.20944/preprints202301.0489.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
multidrug resistance; MDR; EPB (Xenorhabdus; (X. budapestensis; X. szentirmaii; X. innexii); and Photorhabdus) species); CFCM (cell-free conditioned media); NR-AMP (non-ribosomal-templated antimicrobial peptides); anti-microbial; (anti-bacterial; - anti-coccidial; -anti-protist; - activity; cytotoxicity; in vitro; in situ (local) bioavailablity; XENOFOOD; allometry
Online: 27 January 2023 (06:21:56 CET)
ARTICLE
|
doi:10.20944/preprints201810.0088.v1
Subject:
Chemistry And Materials Science,
Biomaterials
Keywords:
There are many molecules used as drug carrier. TUD-1 is a newly synthesized mesoporous silica (SM) molecule possess two important features; consists of mesoporous so it is very suitable to be drug carrier in addition to that it has the ability to induce apoptosis in cancer cells. However, the effect of TUD-1 appears to act as cell death inducer, regardless of whether it is necrosis or apoptosis. Unfortunately, recent studies indicate that a proportion of cells undergo necrosis rather than apoptosis, which limits the use of TUD-1 as a secure treatment. On the other hand, lithium considered as necrosis inhibitor element. Hence, current study based on the idea of production a new Li/TUD-1 by incorporated mesoporous silica (TUD-1 type) with lithium in order to produce a new compound that has the ability to activate apoptosis by mesoporous silica (TUD-1 type) and at the same time can inhibit the activity of necrosis by lithium. Herein, lithium was incorporated in TUD-1 mesoporous silica by
Online: 4 October 2018 (15:54:02 CEST)