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Preprint REVIEW | doi:10.20944/preprints202404.1000.v1

Telomeres and Telomerase as Promising Targets for Malaria Therapy: A Comprehensive Review

Theophilus Nang Wakai, Dorathy Olo Anzaku, Israel Sunmola Afolabi

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: Malaria; Telomeres Maintenance; Plasmodium; Therapeutic Target

Online: 16 April 2024 (07:39:39 CEST)

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Preprint REVIEW | doi:10.20944/preprints202404.0659.v1

Gerontogen as the Toxicology of Aging

Rahma Rahma, Agian Jeffilano Barinda

Subject: Medicine And Pharmacology, Pharmacology And Toxicology Keywords: aging; senescence; toxicology; gerontogen; senotherapy

Online: 10 April 2024 (03:17:10 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.0505.v1

Inspiring Sustainability in Undergraduate Engineering Programs

Tina Griesinger, Kenneth Reid, David Knight, Andrew Katz, John Somers

Subject: Engineering, Other Keywords: environmental sustainability; engineering education; learning experiences; career interests

Online: 8 April 2024 (08:30:57 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202403.1553.v1

Environmental Accounting Disclosures and Financial Performance of Listed Oil and Gas Companies in Nigeria: An Application of Driscoll-Kraay Standard Errors Approach

Adegboyega R. Afolabi, Olayemi Oluwadamilola Amosun, Solomon Oluwaseun Okunade, MaryAnn Njong Agbor

Subject: Business, Economics And Management, Finance Keywords: environmental accounting; financial performance; oil and gas companies; Nigeria; Driscoll-Kraay standard errors

Online: 26 March 2024 (10:48:56 CET)

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Preprint ARTICLE | doi:10.20944/preprints202402.0512.v1

Dazzling Evaluation of High-repetition-rate CO2 Pulsed Laser on Infrared Imaging Systems

Hanyu Zheng, Yunzhe Wang, Yang Liu, Tao Sun, Junfeng Shao

Subject: Engineering, Electrical And Electronic Engineering Keywords: Laser dazzling; edge extraction; contour curvature; target detection

Online: 8 February 2024 (10:42:38 CET)

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Preprint ARTICLE | doi:10.20944/preprints202403.0916.v1

Effects of Specific Training Using a Rowing Ergometer on Sport Performance in Adolescents

Juan Gavala-González, Mª Elena Porras-García, José Carlos Fernández-García, Mateo Real-Pérez

Subject: Public Health And Healthcare, Physical Therapy, Sports Therapy And Rehabilitation Keywords: rowing; sport performance; adolescents

Online: 15 March 2024 (11:47:33 CET)

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Preprint CASE REPORT | doi:10.20944/preprints202409.1967.v1

Cervical Mesonephric Adenocarcinoma Treated with Neoadjuvant Chemotherapy. A Case Report and a Literature Review

Hiroaki Ishida, Megumi Manrai, Hiroki Egashira, Mizuki Nonaka, Nobuyuki Hiruta, Reiko Watanabe, Akiko Takashima

Subject: Medicine And Pharmacology, Obstetrics And Gynaecology Keywords: Cervical mesonephric adenocarcinoma; Neoadjuvant chemotherapy; Adjuvant chemotherapy

Online: 25 September 2024 (08:52:06 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202408.0131.v1

Salmonella Inactivation Model by UV-C Light Treatment in Chicken Breast

Rosa María García-Gimeno*, Guiomar Denisse Posada-Izquierdo, Eva Palomo-Manzano, Poliana Mendes de Souza

Subject: Public Health And Healthcare, Other Keywords: non-thermal treatment; UV-C; low transmittance food; mathematical modelling; foodborne pathogens

Online: 2 August 2024 (06:04:32 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202407.1425.v1

Effect of Biomass Burnings on Population Exposure and Health Impact at the End of 2019 Dry Season in Southeast Asia

Hiep Duc Nguyen, Bang Quoc Ho, Quan Hong Nguyen, Quang Xuan Ngo, Duong Anh Tran

Subject: Environmental And Earth Sciences, Environmental Science Keywords: Southeast Asia; biomass burnings; dry season 2019; health impact; PM2.5 pollutants

Online: 17 July 2024 (11:36:28 CEST)

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Preprint REVIEW | doi:10.20944/preprints202404.0054.v1

Proteomic Insights into Osteoporosis: Unraveling Diagnostic Markers and Therapeutic Targets for the Metabolic Bone Disease

Jihan Wang, Mengju Xue, Ya Hu, Jingwen Li, Zhenzhen Li, Yangyang Wang

Subject: Biology And Life Sciences, Life Sciences Keywords: osteoporosis; bone metabolism; proteomics; diagnostic biomarkers; therapeutic targets

Online: 1 April 2024 (17:09:17 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202408.2075.v1

3D Reconstruction of Indoor Scenes Based on Neural Implicit

Zhaoji Lin, Yutao Huang, Li Yao

Subject: Computer Science And Mathematics, Computer Vision And Graphics Keywords: 3D reconstruction; indoor scene; neural radiance fields; signed distance function; normal prior; mesh

Online: 29 August 2024 (03:13:26 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202408.0986.v1

Beyond Profit. Exploring the Motivators of Local Producers in Multiple Sub-regions in Western Hungary

András Schlett, Marietta Balázsné Lendvai, Judit Beke

Subject: Social Sciences, Other Keywords: Local producers, Sustainable producer attitudes, Mental and spiritual well-being, Autotelic factors, Hungary, Local identity, Local entrepreneurship, Work well-being

Online: 14 August 2024 (09:07:51 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202406.0707.v1

Energy Management System for an Industrial Microgrid using Optimization Algorithms based Reinforcement Learning Technique

Saugat Upadhyay, Ibrahim Ahmed, Lucian Mihet-Popa

Subject: Engineering, Electrical And Electronic Engineering Keywords: EMS; PPO; BESS; Optimization Algorithm; Peak Shaving; Price Arbitrage

Online: 11 June 2024 (11:41:32 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202405.1872.v1

Proline Metabolism Genes in Transgenic Plants: Meta-Analysis under Drought and Salt Stress

Marco Renzetti, Elisa Bertolini, Maurizio Trovato

Subject: Biology And Life Sciences, Plant Sciences Keywords: proline metabolism genes; drought tolerance; salinity tolerance; transgenic plants; meta-analysis

Online: 29 May 2024 (07:00:23 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202403.1295.v1

Investigation on Cement Stabilized Base with Recycled Aggregate and Desert Sand

Fengchao Liu, Yongjun Qin, Yiheng Yang

Subject: Engineering, Civil Engineering Keywords: Recycled coarse aggregate; Desert sand; Cement-stabilized macadam; Mechanical property; Microstructure

Online: 22 March 2024 (07:53:02 CET)

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Preprint ARTICLE | doi:10.20944/preprints202403.1068.v1

Charting the Ethical Frontier in Newborn Screening: Insights from the NBSTRN ELSI Researcher Needs Survey

Yekaterina Unnikumaran, Kee Chan, Amy Brower

Subject: Public Health And Healthcare, Public Health And Health Services Keywords: Newborn Screening, Ethical, Legal, Social Issues, ELSI, Research, Rare Disease,, NBSTRN, Privacy, Informed Consent.

Online: 19 March 2024 (10:22:27 CET)

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Preprint ARTICLE | doi:10.20944/preprints202403.0825.v1

Revitalising the Coastal Landscape of Qatar: The Urban Renewal Approach in Westbay

Shikha Patel, Deepthi John, Raffaello Furlan, Deepthi John

Subject: Engineering, Architecture, Building And Construction Keywords: coastal land reclamation; urban planning; urban policy; assessment framework; sustainable development; sustainability indicators.

Online: 14 March 2024 (05:58:15 CET)

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Preprint ARTICLE | doi:10.20944/preprints201612.0151.v1

Expression and Potential Function of Plasma Exosomal microRNAs (miR-483-5p, miR-671-5p, and miR-150-3p) in a Mouse Mode and in Mesial Temporal Lobe Epilepsy Patients

Shaofeng Yan, Guiyang Liu, Wenyan Xie, Dawei Meng, Hua Zhang, Fangang Meng, Kai Zhang, Yin Jiang, Xin Zhang, Jianguo Zhang

Subject: Biology And Life Sciences, Anatomy And Physiology Keywords: epilepsy; exosoma; microRNA

Online: 30 December 2016 (07:43:42 CET)

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Preprint ARTICLE | doi:10.20944/preprints202409.1173.v1

Risk of Hepatitis B Virus Reactivation in COVID-19 Patients Receiving Immunosuppressive Treatment – Prospective Study

Nicoleta Mihai, Mihaela Cristina Olariu, Oana-Alexandra Ganea, Aida-Isabela Adamescu, Violeta Molagic, Ștefan Sorin Aramă, Cătălin Tilișcan, Victoria Aramă

Subject: Medicine And Pharmacology, Epidemiology And Infectious Diseases Keywords: SARS-CoV-2; COVID-19; immunosuppressive agents; hepatitis B virus; reactivation

Online: 17 September 2024 (05:09:04 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202408.1617.v1

Analysis of Adipose Tissue Characteristics and Lipid Metabolism in Natural Grazing Mongolian Cattle

Xueting Yu, Lu Chen, Xige He, Yunfei Han, Yajuan Huang, Jindi Wu, Rina Sha, Gerelt Borjigin

Subject: Biology And Life Sciences, Animal Science, Veterinary Science And Zoology Keywords: Mongolian cattle; Subcutaneous fat; Fat color; Lipids

Online: 22 August 2024 (08:25:07 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202407.0720.v1

Dietary Probiotic Prototypes and Their Effects on Growth Performance, Immune Function, and Gut Microbiota of Rainbow Trout (Oncorhynchus mykiss)

Sahar Mahmoodian, Amir Meimandipour, Monireh Faeed, Mehdi Shamsara, Javad Daghigh roohi, Seyed Safa-Ali Fatemi, Mohades Ghasemi, Mahsa Chaharmahali

Subject: Biology And Life Sciences, Aquatic Science Keywords: Rainbow trout; Probiotics; Growth performance; Immunity; Gut microbiota; liver enzymes; Blood parameters

Online: 9 July 2024 (08:47:24 CEST)

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This study investigated the development of novel probiotic formulations specifically designed for rainbow trout aquaculture. The project evaluated the effects of two formulations containing potential probiotic strains isolated from rainbow trout itself. These effects were assessed on various parameters including growth performance, immune response, liver enzyme activity, gene expression related to immunity, and the composition of the bacterial gut microbiota in rainbow trout (Oncorhynchus mykiss). In a completely randomized experimental design, a total of 450 rainbow trout were randomly divided into 70-liter fiberglass tank. The study included six treatments of three replicates (n=18 tanks). Six dietary treatments were included (A) and (B) containing three strains of Pediococcus sp P15, Lactococcus lactis ml3, Weissella cibaria ml6 at two dosages (300 and 500 mg/kg), treatments (C) and (D) containing five strains of P. sp P15, L. lactis ml3, W. cibaria ml6, Enterococcus faecium E10 and Lactobacillus curvatus 13A at two dosages (300 and 500 mg/kg), a commercial probiotic (E) at 300 mg/kg, and a control group (F) without probiotics. Treatments of (A), (B) and (E) resulted in the highest final weights in compared to control group. Fish fed treatments (A) and (B) had the lowest FCR than other groups. Treatments (A) and (D) showed a significant increase in immunoglobulin M (IgM) concentration compared to other groups. The expression of tumor necrosis factor (TNF) was significantly lower in group (A) than the control. In contrast, the expression of interleukin 6 (IL6) and immunoglobulin T (IgT) was increased 4.4-fold and 41-fold, respectively, in group (A) compared to control group. Among the probiotic fed treatments, group (A) showed a significant higher number of lactic acid bacteria compared to other groups during the experiment. This study highlights the significant role of treatment (A) containing three strains of P. sp P15, L. lactis ml3, and W. cibaria ml6 at a dosage of 300 mg/kg as a potential probiotic product for the rainbow trout industry.

Preprint ARTICLE | doi:10.20944/preprints202406.1774.v1

Dynamic Characterization of Microscopic Pore Structure in Mid-High Permeability Sandstones during Long-term Water-flooding

Jiayi Wu, Yan Zhu, Yuhang He, Qingyu Wang, Junhui Guo, Shuai Shao, Rubin Li, Yi Bao

Subject: Engineering, Energy And Fuel Technology Keywords: Pore classification; local permeable capacity; pore size; mid-high permeability sandstone; pore structure variation; long-term waterflooding

Online: 26 June 2024 (06:33:25 CEST)

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Most of the mid-high permeability sandstone oilfields in China have entered the ultra-high water cut stage, accompanied with the highly-dispersed residual oil, and the control effect of mi-cro-heterogeneity on the residual oil is increasingly prominent. Understanding the microscopic characteristics of pore structural and its evolution during the long-term waterflooding is critical for enhancing the accuracy and efficiency of oil field exploitation. While the previous insights paid more attention to the geometrical and morphological features of pore structure and ignores the relation of pore structure with the fluid flow capacity. In this study, we propose a microscopic pore structure classification method considering pore size and local permeable capacity, which realizes the physical classification and quantitative evaluation of pore structure characteristics for different permeability rocks. The micro-pore structure is classified into 6 types based on the key evaluation parameters of pore diameter and flow flux area. By taking six mid-high permea-bility sandstone core samples from Daqing oilfield in China, a series of long-term waterflooding experiments are carried out and the interior pore structure was captured using high precision CT scanning technique. The results reveals that high-permeability reservoirs exhibit concentrated pores diameters and finer throats, whereas mid-permeability reservoirs exhibit smaller pores and throats in greater quantity. With the increase of water injection volumes, the permeable ca-pacity and connectivity of the high-connectivity pore space in ultra-high- and high-permeability reservoirs are enhanced, and in mid-permeability reservoirs, the micro-heterogeneity intensifies the increase in low-connectivity small pores. These findings provide new insights for the micro-scopic heterogeneity and a solid theoretical basis for investigating the occurrence of microscopic residual oil and optimising enhanced oil recovery strategies at the late stage of ultra-high water cut.

Preprint ARTICLE | doi:10.20944/preprints202406.0764.v1

Study of Plant Biodiversity of Various Gorges of the Mountain System of Western Karatau Based on the Important Plant Areas (Mangistau, Kazakhstan)

Imanbayeva Akzhunis, Mukhtubayeva Saule, Duisenova Nurzhaugan, Adamzhanova Zhanna, Zharassova Dinara, Orazov Aidyn, Musaeva Zhanna, Lukmanova Akimzhan

Subject: Biology And Life Sciences, Plant Sciences Keywords: biodiversity; biogeography; arid land; important plant areas; phytosociology; plant communities

Online: 12 June 2024 (08:16:26 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202402.1630.v1

The Use of Sargassum spp. Ashes Like a Raw Material for Mortars Production: Composite Performance and Environmental Outlook

Gabriela Pitolli Lyra, Ana Letícia Colombo, Afonso José Felício Peres Duran, Igor Machado da Silva Parente, Cristiane Bueno, João Adriano Rossignolo

Subject: Engineering, Architecture, Building And Construction Keywords: Seaweed Ash; Cementitious Composites; Biomass; Civil Construction; LCA

Online: 28 February 2024 (12:06:04 CET)

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The accumulation of brown algae from the genus Sargassum has been increasing over the years in coastal regions of the Caribbean, Africa, Brazil, and Mexico. This causes harmful effects to the ecosystem, health, economy, and climate due to gas emissions from its decomposition process. There is the possibility of this biomass being reused in civil construction, and few studies have been carried out on its application to common Portland cement mortar. As such, the objective of this study is to evaluate the potential of sargassum ash as a mineral addition to partial replacement of fine aggregates in Portland cement mortar. Characterizations of the raw materials were carried out through X-ray fluorescence spectroscopy, loss on ignition, particle size distribution, Brunauer–Emmett–Teller (BET), real density, X-ray diffraction, scanning electron microscopy, and dispersion spectroscopy of electrons. The mortars were prepared by partially replacing the fine aggregate (sand) with sargassum ash, at 0%, 5%, 10% and 20%. Mortar performance was evaluated through water absorption, apparent porosity, apparent specific mass, compressive strength after 7, 28, and 63 days after curing. Lastly, a life cycle assessment in accordance with ISO standards 14040:2006 and 14044:2006. The results showed that replacing sand with sargassum ash increases water absorption, apparent porosity, and decreases the apparent specific mass and compressive strength as replacement increases. Nevertheless, the compressive strength results after 63 days, for 5 and 10% replacement did not differ statistically from reference values. The life cycle assessment indicates that mortars with partial replacement of sand by sargassum ash showed positive environmental impacts when compared to reference values for most categories regardless of the scenario analyzed, especially for mortar with 10% replacement. As such, the use of sargassum ash at 10% does not alter compressive strength values after 63 days while reducing its environmental impact. The application of this biomass in civil construction materials provides a destination for this algae that has been causing several social, environmental, and economic problems.

Preprint ARTICLE | doi:10.20944/preprints202402.1027.v1

TRIM2 Selectively Regulates Inflammation-Driven Pathological Angiogenesis without Affecting Physiological Hypoxia-Mediated Angiogenesis

Nathan K.P. Wong, Emma L. Solly, Richard Le, Victoria A. Nankivell, Jocelyne Mulangala, Peter J. Psaltis, Stephen J. Nicholls, Martin K.C. Ng, Christina A. Bursill, Joanne T.M. Tan

Subject: Biology And Life Sciences, Cell And Developmental Biology Keywords: Inflammation; Ischemia; Neovascularization; HIF-1α ; eNOS

Online: 19 February 2024 (08:33:17 CET)

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Preprint ARTICLE | doi:10.20944/preprints202407.1185.v1

Follicular Immune Landscaping Reveals a Distinct Profile of FOXP3hi CD4+ T Cells in Treated Compared to Untreated HIV

Spiros Georgakis, Michail Orfanakis, Cloe Brenna, Simon Burgermeister, Perla Mariana Del Rio Estrada, Mauricio Gonzalez Navarro, Fernanda Torres-Ruiz, Gustavo Reyes Terán, Santiago Avila Rios, Yara Andrea Luna-Villalobos, Oliver Y. Chen, Giuseppe Pantaleo, Richard A. Koup, Constantinos Petrovas

Subject: Biology And Life Sciences, Immunology And Microbiology Keywords: HIV; germinal center; imaging; CD4 T cells

Online: 16 July 2024 (03:17:26 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202408.0074.v1

Series Solution and Its Extension for the Nonlinear Flow Response of Soft Hair Beds

Bo Hua Sun, Bo Pang, Meng Li

Subject: Physical Sciences, Fluids And Plasmas Physics Keywords: soft hair beds; Stokes flow; series solution; perturbation solution

Online: 6 August 2024 (03:11:27 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202407.0555.v1

The Effect of Monthly Disposable Soft Contact Lenses on Retinal Straylight

Gatis Ikaunieks, Inese Petrovica

Subject: Public Health And Healthcare, Public, Environmental And Occupational Health Keywords: retinal straylight; soft contact lenses; quality of vision

Online: 8 July 2024 (12:21:38 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202405.2042.v2

Blended Learning and Flipped Classroom in Higher Engineering Education: Case Study and Students’ Perception in the Post-COVID-19 Period

Andrzej Ożadowicz

Subject: Engineering, Electrical And Electronic Engineering Keywords: blended learning; flipped classroom; e-learning; learning management system; engineering higher education; ICT; building automation

Online: 4 June 2024 (08:17:45 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1614.v1

Impacts of Land Use Transition on Ecosystem Services in the Dongting Lake Area

Xuan Shi, Qimeng Ning

Subject: Environmental And Earth Sciences, Sustainable Science And Technology Keywords: ecosystem service; Dongting Lake area; land use transitions; InVEST model; GWR

Online: 1 May 2024 (04:24:11 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201611.0107.v1

Inhibition of Autophagy by Deguelin Sensitizes Pancreatic Cancer Cells to Doxorubicin

Xiao-Dong Xu, Yan Zhao, Min Zhang, Rui-Zhi He, Xiu-Hui Shi, Xing-Jun Guo, Cheng-Jian Shi, Feng Peng, Min Wang, Min Shen, Xin Wang, Xu Li, Ren-Yi Qin

Subject: Medicine And Pharmacology, Gastroenterology And Hepatology Keywords: pancreatic cancer; deguelin; autophagy; doxorubicin

Online: 21 November 2016 (10:01:23 CET)

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Preprint ARTICLE | doi:10.20944/preprints202408.2081.v1

Prevalence, Characteristics, and Awareness of Chronic Kidney Disease in Croatia. The EH-UH 2 Study

Ana Jelaković, Danilo Radunović, Josipa Josipović, Tajana Željković Vrkić, Lana Gellineo, Marija Domislović, Vladimir Prelević, Marijana Živko, Mirjana Fuček, Mihaela Marinović Glavić, Nikolina Bašić‐Jukić, Ivan Pećin, Marija Bubaš, Krunoslav Capak, Bojan Jelaković

Subject: Public Health And Healthcare, Public, Environmental And Occupational Health Keywords: albuminuria; awareness; chronic kidney disease; cardiovascular risk; eGFR (CKD Epi) formula; glomerular filtration rate; national population survey

Online: 28 August 2024 (14:45:52 CEST)

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Preprint REVIEW | doi:10.20944/preprints202408.2025.v1

Evolution of Auriferous Fluids in the Kraaipan-Amalia Greenstone Belts: Evidence from Mineralogical and Isotopic Constraints

Kofi Adomako-Ansah, Napoleon Quaye Hammond, Yuichi Morishita, Daizo Ishiyama

Subject: Environmental And Earth Sciences, Geophysics And Geology Keywords: Kraaipan; Amalia; greenstone belt; gold; oxide BIF; strontium isotopes; South Africa; Kaapvaal Craton

Online: 28 August 2024 (10:41:25 CEST)

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The Kraaipan and Amalia greenstone belts in South Africa occurs in the western part of the Kaapvaal Craton. The two belts stretch discontinuously in an approximately north-south orientation over a distance of about 250 km from southern Botswana in the north to the Vaal River near Christiana in the south and are separated by a distance of about 90 km. Gold mineralization is hosted in banded iron-formation at both the Kalahari Goldridge deposit (Kalgold) in the Kraaipan greenstone belt in the north, and the Amalia deposit in the Amalia greenstone belt in the south, with the mineralization associated with quartz-carbonate veins. The footwall of these deposits is generally composed of mafic volcanic schist and hanging wall consisting of graywackes, schist and shale units. The Kalgold and Amalia gold deposits show some variation in the redox condition of the mineralizing system, mineralization temperatures and fluid chemistry. The ore mineral assemblage is characterized by magnetite-pyrrhotite-pyrite at Kalgold, which is indicative of reducing conditions, and magnetite-hematite-pyrite assemblage at Amalia that suggest a relatively oxidizing environment. Average mineralizing temperatures determined from chlorite geothermometry were relatively higher at the Kalahari Goldridge deposit ranging from 350 to 400oC compared to 335 to 370oC (mean, 352± 18, n = 113) at Amalia. The composition of the fluids derived from fluid inclusions are indicative of low salinity H2O-CH4-CO2-rich fluids at Kalgold against relatively H2O-CO2-rich fluids at Amalia. Evidence from strontium-carbon-oxygen isotopic ratios from carbonates suggests differences in redox conditions in the deposits could be attributed to different flow pathways by the evolving fluid from a common source (with minimum 87Sr/86Sr=0.70354) to the sites of gold deposition; with significant ore fluid interaction with thick sequence of carbonaceous meta-pelitic rock units at the Kalahari Goldridge deposit, that is absent in the Amalia deposit.

Preprint ARTICLE | doi:10.20944/preprints202408.0546.v1

Corrosion Behaviour of Weld Metal of Ultra-High Strength Steels Weldments in a Sodium Chloride Aqueous Solution

Mariana Dimitrova Ilieva, Danail Dimitrov Gospodinov, Nikolay Vasilev Ferdinandov, Rossen Hristov Radev

Subject: Chemistry And Materials Science, Materials Science And Technology Keywords: ultra-high strength steel; weldments; weld metal; corrosion; microstructure; potentiodynamic scan

Online: 8 August 2024 (12:37:23 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202408.0207.v1

Ordered versus Non-Ordered Mesoporous CeO₂-Based Systems for the Direct Synthesis of Dimethyl Carbonate from CO₂

Nicoletta Rusta, Fausto Secci, Valentina Mameli, Carla Cannas

Subject: Chemistry And Materials Science, Materials Science And Technology Keywords: CO₂ utilization; dimethyl carbonate; ceria; mesoporous; nanocomposites; catalysis

Online: 6 August 2024 (03:39:27 CEST)

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Preprint REVIEW | doi:10.20944/preprints202407.1092.v1

Recent Advances and Future Perspectives in Vascular Organoids and Vessel-on-Chip

Gowtham Reddy Cheruku, Chloe Veronica Wilson, Suriya Raviendran, Qingzhong Xiao

Subject: Medicine And Pharmacology, Cardiac And Cardiovascular Systems Keywords: Vascular organoid; Vessel-on-chip; Pluripotent stem cell; Induced pluripotent stem cell, Cardiovascular disease; Vascular disease

Online: 14 July 2024 (03:11:49 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202406.0079.v1

Investigation of Toughening Mechanisms in Elastomeric PC Blends through Morphological and Mechanical Characterization at Small and Medium Strain Rates

Pedro Veiga Rodrigues, Bruno Ramoa, Maria Cidália R. Castro, Ana Vera Machado

Subject: Chemistry And Materials Science, Polymers And Plastics Keywords: polycarbonate elastomeric blends; toughening mechanism; small strain rate; medium strain rate

Online: 6 June 2024 (03:12:19 CEST)

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Preprint REVIEW | doi:10.20944/preprints202405.1308.v1

Navigating the Future of PHA Composites: A Review of Challenges and Opportunities

Abhishek Thakur, Marta Musiol̥, Khadar Duale, Marek Kowalczuk

Subject: Chemistry And Materials Science, Biomaterials Keywords: polyhydroxyalkanoate (PHA); polymer composites; biocomposites; waste natural fillers

Online: 20 May 2024 (16:49:56 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1782.v1

Efficient Refinement of Complex Structures of Flexible Histone Peptides Using Post-Docking Molecular Dynamics Protocols

Bayartsetseg Bayarsaikhan, Balázs Zoltán Zsidó, Rita Börzsei, Csaba Hetényi

Subject: Computer Science And Mathematics, Mathematical And Computational Biology Keywords: peptide; histones; docking; refinement; molecular dynamics; water

Online: 26 April 2024 (19:23:39 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202402.1387.v1

Assessment of Sugar-Related Dietary Patterns to Personality Traits, Cognitive-Behavioural and Emotional Functioning in Women

Agnieszka Garbacz, Bogusław Stelcer, Michalina Wielgosik, Magdalena Czlapka-Matyasik

Subject: Biology And Life Sciences, Food Science And Technology Keywords: sweet taste preferences; diet; personality traits

Online: 23 February 2024 (16:20:32 CET)

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Preprint ARTICLE | doi:10.20944/preprints201612.0139.v1

A Kinematic Model to Compensate the Structural Deformations in Machine Tools Using Fibre Bragg Grating (FBG) Sensors

Francesco Aggogeri, Alberto Borboni, Rodolfo Faglia, Angelo Merlo, Nicola Pellegrini

Subject: Engineering, Mechanical Engineering Keywords: kinematic model; fiber Bragg grating; deformations; machine tools calibration; predicted model; multiple regression analysis; finite element analysis

Online: 29 December 2016 (07:39:26 CET)

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Preprint ARTICLE | doi:10.20944/preprints201611.0089.v1

Estimation of the Daily Salt Intake by 24-Hour Urinary Sodium Excretion in Morocco: A Pilot Study

Abdelfettah Derouiche, Younes El-Kardi, Karima Mohtadi, Ali Jafri

Subject: Medicine And Pharmacology, Urology And Nephrology Keywords: hypertension; salt intake; urinary excretion; Morocco

Online: 17 November 2016 (10:49:28 CET)

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Preprint ARTICLE | doi:10.20944/preprints202406.1163.v1

Assessment of the Efficacy of the Antihistamine Drug Rupatadine Used Alone or in Combination against Mycobacteria

Xirong Tian, Wanli Ma, Buhari Yusuf, Biyi Su, Jinxing Hu, Tianyu Zhang

Subject: Medicine And Pharmacology, Medicine And Pharmacology Keywords: Mycobacteria; Drug resistance; Rupatadine; Drug repurposing; Nonreplicating

Online: 17 June 2024 (15:53:28 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202405.0611.v1

Plastid Phylogenetics, Biogeography and Character Evolution of the Chinese Endemic Genus Sinojackia Hu.

Xing Jian, Yuliang Wang, Qiang Li, Yongmei Miao

Subject: Biology And Life Sciences, Forestry Keywords: Sinojackia; Plastome; Species delimitation; Evolutionary history

Online: 13 May 2024 (04:31:54 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202409.1855.v1

Antimicrobial Susceptibility of Uropathogenic Escherichia coli with Analysis of Impact of Socio-Economic Factors in Low, Medium and High-Income Countries

Meher Rizvi, Maria Khan, Amina AL Jardani, Ujjala Ghoshal, Zaaima AL Jabri, Mohammad Ahanjan, Azza AL Mamari, Nawal AL Shizawi, Hiba Sami, Abdullah Balkhair, Adila Shaukat, Alwarith Nasser Salem Alkharusi, Abdulrahman Almahrouqi, Afreenish Hassan, Ajay Kumar, Amal Malehi, Amina Gul, Ashima Singh, Asma Said Hamed AL Shidhani, Areena Hoda Siddiqui, Aruna Poojary, Azza AL Rashdi, Bradley Langford, Dmytro Stepanskyi, Abbas Dolatabadi, Aisha Al Mufraji AL Mufraji, Elham Said Ahmed AL Risi, Garima Kapoor, Isabella Princess, Hatim Ali Eltahir, Hilal Al Sidairi, Kaitlyn Dougherty, Katia Iskandar, Ken Masters, Ibrahim Khalaf Hamdan AL Busaidi, Laila AL Yazidi, Mahfuza Nasrin, Mahmood Salim AL Subhi, Mallika Sengupta Mallika Sengupta, Manisha Khandait, Nada Khalfan AL Tamtami, Nada Khafan Alsiyabi, Nawal AL Kindi, Nazla Musthafa Luthfee, Neha Shreshtha, Nihal Mohamed Amur AL Riyami, Noora Hilal Ali AL Busaidi, Nupur Goel, Oksana Ishchenko, Omnia Mohamed Elnabawy Ahmed Taher, Pragnya Paramita Jena, Rajni Ekadashi, Razan Zadjali, Reba Kanungo, Sara Abolghasemi, Salima Al-maqbali, Sanjay Jaju, Sayantan Banerjee, Shadma Yaqoob, Shahnaz Sali, Shafqat Husnain Khan, Shalini Malhotra, Stephen Hughes, Sundas Shaukat, Syed Mohammed Atif, Vrushali Vishwas Patwardhan, Victorien Dougnon, Wahid Khan, Walid Wali, Zakariya AL Muharrmi, Zeeshana Basit, Jasashree Choudhury, Rachita Pravalina, Sanjeev Singh, Sarman Singh, Neelam Taneja, Raman Sardana, Pawan Kapoor, Rajeev Soman, Rashid Al Abri

Subject: Medicine And Pharmacology, Epidemiology And Infectious Diseases Keywords: community acquired UTI; Escherichia coli; antimicrobial susceptibility; Indian subcontinent; MENA; GDP; temperature

Online: 24 September 2024 (12:32:05 CEST)

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Preprint REVIEW | doi:10.20944/preprints202408.1413.v1

Reactive Oxygen Species Mechanisms That Regulate Protein-Protein Interactions in Cancer

Stavros Iliadis, Nikolaos A Papanikolaou

Subject: Medicine And Pharmacology, Oncology And Oncogenics Keywords: ROS; PPI; cancer; degradation; phosphorylation; kinases; phosphatase

Online: 20 August 2024 (12:04:15 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202409.0524.v1

Differences in Diet Assessment and Body Composition among Young Spanish Elite Footballers: Morning Training vs. Evening Training

Antonio Almendros-Ruiz, Jose Antonio Latorre, Javier Conde-Pipo, José Fernández-Martínez, Darío Acuña-Castroviejo, Bernardo Requena, Miguel Mariscal-Arcas

Subject: Medicine And Pharmacology, Dietetics And Nutrition Keywords: football; soccer; body composition; exercise time of day; training schedule

Online: 6 September 2024 (10:55:46 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202408.2214.v1

Nature of Charge Transfer Effects in Complexes of Dopamine Derivatives Adsorbed on Graphene-Type Nanostructures

Alex-Adrian Farcas, Attila Bende

Subject: Physical Sciences, Chemical Physics Keywords: TDDFT; charge-transfer; Graphene; Dopamine; Zwitterion; Quinone

Online: 30 August 2024 (04:57:55 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202406.0893.v1

Sweat Electrolyte Detection Patch for Non-invasive Hydration Monitoring

Jorge A. Rodriguez, Daniela Diaz-Alonso

Subject: Engineering, Bioengineering Keywords: electrolyte sensor; galvanic cell; sweat ions; electrolyte; hydration levels

Online: 13 June 2024 (11:51:46 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202408.1294.v1

Comprehensive Risk and Efficacy Analysis of Emergency Medical Response Systems in Serbian Healthcare: Assessing Systemic Vulnerabilities in Disaster Preparedness and Response

Vladimir M. Cvetković, Jasmina Tanasić, Renate Renner, Harald Raupenstrauch, Vanja Rokvić, Hatidža Beriša

Subject: Public Health And Healthcare, Public Health And Health Services Keywords: risk; disaster; emergency preparedness; efficacy; comprehensive survey; emergency medical response systems; vulnerabilities; Serbian healthcare

Online: 19 August 2024 (12:16:43 CEST)

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Emergency Medical Response Systems (EMRS) play a vital role in delivering medical aid during disasters. In Serbia, these systems encounter several obstacles due to economic limitations, scarce resources, and ongoing healthcare reforms, all of which affect their performance. This study focuses on examining the risk factors and effectiveness of Serbia's EMRS, identifying systemic issues, and proposing enhancements to improve emergency preparedness for disasters. A survey was conducted across healthcare institutions in Serbia to gather comprehensive insights. The survey explored various aspects, including organizational structures, resource distribution, communication systems, and the speed of emergency responses. Statistical methods such as Pearson's correlation, multivariate regression analysis and chi-square tests were utilized to interpret data collected from 172 healthcare institutions. The multivariate regression analysis of EMS organization identified that factors such as the structuring of working hours and shift patterns are significant predictors, contributing to small but meaningful variations in various EMS outcomes. In contrast, other factors, such as financial resources and the availability of ambulance vehicles, showed more targeted significance depending on the specific EMS aspect being analyzed. Institutions with written mass casualty plans and procedures demonstrate superior effectiveness in EMS activities, excelling in resource allocation, operational continuity, and emergency preparedness, particularly through enhanced coordination and specialized systems for managing large-scale emergencies. The findings highlighted notable disparities in how EMRS are organized, with only 46% of institutions having specific emergency departments. Resource limitations were evident, as many facilities operated with minimal staff and outdated equipment. The communication systems revealed weaknesses, with just 54% having established protocols for handling emergency calls. Response times frequently surpassed international standards, which negatively affected patient outcomes. Additionally, the study found training deficiencies, with 68% of participants expressing a need for further education. Serbia’s EMRS are significantly impacted by systemic issues such as insufficient funding, disjointed service delivery, and inadequate training. Overcoming these challenges necessitates a comprehensive approach that includes boosting financial support, implementing standardized protocols, and fostering enhanced collaboration across different sectors.

Preprint COMMUNICATION | doi:10.20944/preprints202408.0459.v1

Towards early cancer detection: the use of Caenorhabditis elegans chemotaxis to distinguish patient urine from that of healthy individuals

Alžbeta Kaiglová, Patrícia Hockicková, Zuzana Bárdyová, Radka Reháková, Kamila Melnikov, Soňa Kucharíková

Subject: Biology And Life Sciences, Life Sciences Keywords: Caenorhabditis elegans; cancer; chemotaxis; chemotactic tests

Online: 6 August 2024 (14:52:40 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202407.1716.v1

A Spatial-Seasonal Study for Dynamics of Pollutant Concentration in Water on the Danube River in the Adjacent Danube Delta Area and the Evaluation of the Attenuation and Transfer Coefficients. Part 1 – Case Study – Monitored Heavy Metals

Catalina Topa, Gabriel Murariu, Valentina-Andreea Calmuc, Madalina Calmuc, Maxim Arseni, Cecila Serban, Carmen Lidia Chițescu

Subject: Environmental And Earth Sciences, Environmental Science Keywords: Aluminum; Arsenic; Cadmium; Chromium; Iron; absorption coefficients; numerical approach; flow simulation; HEC-RAS; model unsteady

Online: 22 July 2024 (11:55:13 CEST)

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Monitoring and protecting flowing watercourses is a complex and challenging task that requires the collaboration and coordination of various stakeholders such as governments, industries, farmers, consumers and environmental groups. The study of the dynamics of the concentration of polluting factors and especially the concentrations of heavy metals and highlighting a seasonal variation is a necessary element from this point of view. In this article, we present the results of our analyzes carried out in two measurement campaigns executed in 10 monitoring points along the Danube River, between Braila city and Isaccea city in the pre-deltaic area, during the summer season and autumn season 2022. The importance of this area is given by the fact that the Dan-ube Delta is part of the UNESCO heritage and the monitoring of polluting factors is a necessity in the desire to protect this area. The data measured during the July and August 2022 campaign co-vers a wide range of chemical species: Phosphate, CCO, CBO5, NH4+, N-NO2, N-NO3-, N-Total, P-PO4 3-, SO42-, Cl-, phenols, as well as metals with a harmful effect: Aluminum, Arsenic, Cad-mium, Chromium, Iron. The study includes an evaluation based on the statistical approach of the results to highlight the significant correlations and differences identified between the two data sets. Next, to highlight the obtained results, a numerical model was considered using HEC-RAS and ESRI ArcGis applications in a two-dimensional unsteady flow model in order to get the non-homogenous concentrations’distributions in the studied area. These two-dimensional models have been less studied in the specialized literature. In this way, interesting results could be ob-tained and prediction methods regarding the dynamics of metal concentrations could be struc-tured. The data obtained was used for the terrain model from the USGS service and the flows of the Danube and its two tributaries were simulated using the data provided by the national ser-vices. In this work, we present the results obtained for the dynamics of the concentrations of the metals Aluminum, Arsenic, Cadmium, Chromium and Iron and the evaluation of the specific ab-sorption coefficients for the explanation and correlation with the results of the measurements. The study is part of a more complex project in which the spatio-temporal distribution of the polluting factors in the water was evaluated and the habitats in the study area were inventoried - especially those of community interest. the aspects related to the influence of the distribution of polluting factors on the state of health will be the subject of another article.

Preprint REVIEW | doi:10.20944/preprints202404.0275.v1

The Impact of Nature-Based Outdoor Learning Landscape on STEAM Concept Formation of Preschoolers: A Scoping Review

Nazia Afrin Trina, Muntazar Monsur, Nilda Cosco, Stephanie Shine, Leehu Loon, Ann Mastergeorge

Subject: Social Sciences, Education Keywords: Preschooler; STEAM Concept; Landscape Elements; Informal Learning; Affordances

Online: 5 April 2024 (03:26:52 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202403.0862.v1

Enabling Low-Dose In Vivo Benchtop X-ray Fluorescence Computed Tomography through Deep Learning-Based Denoising

Naghmeh Mahmoodian, Mohammad Rezapourian, Asim Abdulsamad Inamdar, Kunal Kumar, Melanie Fachet, Christoph Hoeschen

Subject: Engineering, Bioengineering Keywords: Deep learning; Artificial Intelligence; Xray Fluorescence; XFCT; AI; DL

Online: 14 March 2024 (12:26:34 CET)

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Preprint ARTICLE | doi:10.20944/preprints202403.0382.v1

Bicarbazole-benzophenone based twisted donor-acceptor derivatives as potential blue emitters for OLEDs

Iram Siddiqui, Prakalp Gautam, Dovydas Blazevicius, Jayakumar Jayakumar, Sushanta Lenka, Daiva Tavgeniene, Ernestas Zaleckas, Jwo-Huei Jou, Saulius Grigalevicius

Subject: Chemistry And Materials Science, Materials Science And Technology Keywords: donor-acceptor derivatives; blue organic light emitting diode; high efficiency; blue emission; thermal analysis

Online: 7 March 2024 (09:34:59 CET)

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Preprint ARTICLE | doi:10.20944/preprints202402.1424.v1

Social Inhibition and Depressive symptoms among Couples Having Children with Autism Spectrum Disorder: The Mediating Role of Perceived Family Support

Ting Pan, Tinakon Wongpakaran, Nahathai Wongpakaran, Bijing He, Danny Wedding

Subject: Medicine And Pharmacology, Psychiatry And Mental Health Keywords: social inhibition; autism; depression; family support; parents; actor partner interdependence mediation model

Online: 26 February 2024 (10:26:06 CET)

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Preprint ARTICLE | doi:10.20944/preprints202406.1706.v1

First Insight into the Incidence of Coxiella burnetii Infection among Veterinary Medicine Students from Bulgaria

Petia Genova-Kalou, Yordan Hodzhev, Ilia Tsachev, Roman Popovich, Stefan Panaiotov, Veselin Dobrinov, Stefka Krumova, Betina Boneva-Marutsova, Borislava Chakarova, Keytlin Todorova, Konstantin Simeonov, Magdalena Baymakova, Pierre-Edouard Fournier

Subject: Biology And Life Sciences, Immunology And Microbiology Keywords: Bulgaria; Coxiella burnetii; Q fever; students; veterinary medicine

Online: 24 June 2024 (14:58:50 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202409.0343.v1

Exploring Floristic Diversity, Propagation Patterns and Plant Functions in Domestic Gardens Across Urban Planning Gradient in Lubumbashi, DR Congo

Yannick Useni Sikuzani, Bernard Kisangani Kalonda, Médard Mpanda Mukenza, Jonas Yona Mleci, Alex Mpibwe Kalenga, François Malaisse, Jan Bogaert

Subject: Environmental And Earth Sciences, Ecology Keywords: urbanization; domestic gardens; plant diversity; socio-economic impact; ecological imbalance; exotic species ;

Online: 4 September 2024 (08:28:53 CEST)

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Urbanization degrades natural habitats and creates new urban ecosystems, like domestic gardens. The plant composition of these gardens varies with socio-economic factors and urban planning levels. However, the diversity and impact of introduced species are often poorly assessed, causing potential ecological imbalances, particularly in Lubumbashi (DR Congo). The objective was to analyze the spatial structure, plant diversity, propagation strategies, and ecological functions of domestic gardens. Three distinct neighborhoods were selected: planned, unplanned and residential neighborhood. 20 avenues (with 5 plots per avenue) were chosen to represent the diversity within each neighborhood, and stratified random sampling of plots was conducted to analyze gardening practices. Gardens were classified into types, and their vegetation was evaluated based on species origin and ecological impact. The analysis of domestic gardens in Lubumbashi reveals significant variations across different neighborhood types. Residential neighborhoods exhibit larger average garden sizes (315.1 m²), higher species richness (22 species), and larger plot sizes (1032 m²) compared to unplanned and planned neighborhoods, where garden areas and species richness are notably lower. Rectangular gardens dominate in unplanned areas, while planned neighborhoods feature more intentional landscaping elements, such as flowerbeds and hedges. The use of gardens for food production is prominent in planned areas (40.7%), whereas residential neighborhoods prioritize ornamentation (51.4%). The study identifies 232 species across 68 families, with a predominance of exotic species (80%) in all neighborhoods, particularly in unplanned areas (82.25%). The data reveals that Mangifera indica and Persea americana are abundant in all neighborhoods, illustrating their adaptability to different urban contexts. Herbaceous species are most common, followed by woody plants, with vines being sparse. Species dispersal is primarily driven by human activities (anthropochory), accounting for over 85% in all neighborhoods. These findings highlight the strong human influence on the composition and structure of domestic gardens in Lubumbashi, emphasizing the dominance of exotic species and the importance of anthropogenic factors in shaping urban green spaces. Urban policies should incorporate strategies to minimize the negative impacts of exotic species on native flora.

Preprint ARTICLE | doi:10.20944/preprints202405.1526.v1

Complete Blood Count-Based Biomarkers as Predictors of Clinical Outcomes in Advanced Non-Small Cell Lung Cancer Patients Treated with First Line Chemoimmunotherapy

Carlo Putzu, Riccardo Serra, Rachele Campus, Giovanni Maria Fadda, Claudio Sini, Andrea Marongiu, Giorgio Carlo Ginesu, Alessandro Giuseppe Fois, Giuseppe Palmieri, Angelo Zinellu, Antonio Cossu, Panagiotis Paliogiannis

Subject: Medicine And Pharmacology, Oncology And Oncogenics Keywords: lung cancer; chemotherapy; immunotherapy; NLR; MNR; biomarkers; blood cell count

Online: 23 May 2024 (09:44:28 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.0567.v1

Immunogenicity of Non-mutated Ovarian Cancer-Specific Antigens

Leslie Hesnard, Catherine Thériault, Maxime Cahuzac, Chantal Durette, Krystel Vincent, Marie-Pierre Hardy, Joël Lanoix, Gabriel Ouellet Lavallée, Juliette Humeau, Pierre Thibault, Claude Perreault

Subject: Medicine And Pharmacology, Immunology And Allergy Keywords: Tumor-specific antigen; Vaccine; Mass spectrometry; Antigen presentation; Immunogenicity; Dendritic cells

Online: 8 April 2024 (15:41:08 CEST)

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Preprint CASE REPORT | doi:10.20944/preprints202405.1909.v1

Equine Corneal Wound Healing Using Mesenchymal Stem Cell Secretome: Case Report

Alejandro Casado-Santos, Elsa González-Cubero, Maria Luisa González-Fernández, Yaiza González-Rodríguez, Belén García-Rodríguez, Vega Villar-Suárez

Subject: Biology And Life Sciences, Animal Science, Veterinary Science And Zoology Keywords: Corneal non-healing ulcer; horses; adipose tissue mesenchymal stem cells; secretome

Online: 29 May 2024 (08:33:12 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201609.0071.v1

Characterization and Development of EST-SSR Markers in Sweet Potato (Ipomoea batatas (L.) Lam)

Jin-Hee Kim, Jun-Hoi Kim, Won-Sam Jo, Jung-Gwan Ham, Il Kyung Chung, Kyung-Min Kim

Subject: Biology And Life Sciences, Plant Sciences Keywords: EST-SSR marker; hexaploid; sweet potato; polymorphic; sequence

Online: 20 September 2016 (11:35:51 CEST)

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According to statistics from the Food and Agriculture Organization, the world population will increase to about 91 million (Asia 51 million, Africa 19 million). A rise in the world’s population means an increased need for food. However, climate change has caused desertification and unpredictable weather, creating problems in the supply and demand of food. Sweet potato (Ipomoea batatas) is an alternative to solving the food problem, as it is one of the world’s most important food crops, especially in developing countries. The tuberous roots of sweet potato are usually used as staple food, animal feed, industrial material, or raw material for alcohol production. In the future, more variations of sweet potato will be needed for breeding this crop. Recently, molecular markers developed for sweet potato have demonstrated good potential for use in genetic selection. In this study, a cDNA library was constructed from the total RNA of sweet potato leaves. A total of 789 copies of the cDNA were cloned in Escherichia coli by employing the pGEM-T Easy vector. Sequencing was carried out by Solgent Co. (Korea). As many as 579 expressed sequence tag–simple sequence repeat (EST-SSR) markers were designed (73.38%) from the known cDNA nucleotide base sequences. The lengths of the developed EST-SSR markers ranged from 100 to 499 bp (average length 238 bp). Their motif sequence types were varied, with most being dinucleotides and pentanucleotides, and the most commonly found motifs were CAGAAT (29.0%) and TCT (2.8%). Based on these SSR-containing sequences, 619 pairs of high-quality SSR primers were designed using WebSat and Primer3web. The total number of primers designed was 144. Polymorphism was evident in 82 EST-SSR markers among 20 Korean sweet potato cultivars tested and in 90 EST-SSR markers in the two parents of a mapping population, Yeseumi and Annobeny. In this study, the hexaploid sweet potato (2n = 6x = 90) EST-SSR markers were developed in the absence of full-sequence data. Moreover, by acting as a molecular tag for particular traits, the EST-SSR marker can also simultaneously identify information about the corresponding gene. These EST-SSR markers will allow the molecular analysis of sweet potato to be done more efficiently. Thus, we can develop high-quality sweet potato while overcoming the challenges from climate change and other unfavorable conditions.

Preprint ARTICLE | doi:10.20944/preprints202407.0749.v1

Size Uniformity of CsPbBr3 Perovskite Quantum Dots via Manganese-Doping

Mi Zhang, Xue Han, Changgang Yang, Guofeng Zhang, Wenli Guo, Jialu Li, Zhihao Chen, Bin Li, Ruiyun Chen, Chengbing Qin, Jianyong Hu, Zhichun Yang, Ganying Zeng, Liantuan Xiao, Suotang Jia

Subject: Chemistry And Materials Science, Nanotechnology Keywords: CsPbBr₃ perovskite quantum dots; manganese-doping; size uniformity; single quantum-dot spectroscopy; narrow-linewidth

Online: 9 July 2024 (16:18:32 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202409.0372.v1

An Explainable AI-based Modified YOLOv8 Model for Efficient Fire Detection

Md. Waliul Hasan, Shahria Shanto, Jannatun Nayeema, Rashik Rahman, Tanjina Helaly, Ziaur Rahman, Sk. Tanzir Mehedi

Subject: Computer Science And Mathematics, Artificial Intelligence And Machine Learning Keywords: fire detection; modified YOLOv8; deep learning; computer vision; explainable artificial intelligence; EigenCAM

Online: 4 September 2024 (12:56:31 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202407.1273.v1

Quill Mites of the Subfamily Syringophilinae (Acariformes: Syringophilidae) Parasitising Starlings (Passeriformes: Sturnidae)

Iva Marcisova, Maciej Skoracki, Milena Patan, Martin Hromada, Bozena Sikora

Subject: Biology And Life Sciences, Parasitology Keywords: Acari; birds; ectoparasites; new species; Sturnidae; Syringophilidae; taxonomy

Online: 16 July 2024 (09:47:26 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201701.0128.v1

The Precipitation Variations in the Qinghai-Xizang (Tibetan) Plateau during 1961-2015

Guoning Wan, Meixue Yang, Zhaochen Liu, Xuejia Wang, Xiaowen Liang

Subject: Environmental And Earth Sciences, Environmental Science Keywords: Precipitation; Tibetan Plateau; trends; temporal-spatial distribution; hydrological cycle;

Online: 29 January 2017 (09:43:00 CET)

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Preprint ARTICLE | doi:10.20944/preprints202408.1384.v1

Characteristic Features of Lif Parameters of Microalgae Alexandrium catenella and Their Dependence on Temperature

Alexander Popik, Sergey Voznesenskiy, Tatiana Dunkay, Evgeniy Gamayunov, Tatiana Orlova

Subject: Physical Sciences, Optics And Photonics Keywords: Alexandrium catenella; Prorocentrum cordatum; HAB; laser-induced fluorescence; fluorescence temperature curves; identification

Online: 20 August 2024 (03:39:19 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202407.1293.v1

Pilot Evaluation of Silicone Surrogates for Oral Mucosa Simulation in Craniofacial Surgical Training

Mitchell Dennis Cin, Krishna Sai Koka, Justin Darragh, Zahra Nourmohammadi, Usama Hamdan, David A. Zopf

Subject: Engineering, Bioengineering Keywords: silicone; mucosa; surgery; craniofacial; otolaryngology; plastics; plastic surgery; education

Online: 16 July 2024 (12:59:17 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202406.1578.v1

Pilot Evaluation of Silicone Surrogates for Oral Mucosa Simulation in Craniofacial Surgical Training

Mitchell Dennis Cin, Krishna Sai Koka, Justin Darragh, Zahra Nourmohammadi, Usama Hamdan, David A. Zopf

Subject: Engineering, Bioengineering Keywords: silicone; mucosa; surgery; craniofacial; otolaryngology; plastics; plastic surgery; education

Online: 24 June 2024 (12:36:58 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202406.1337.v1

Rotating Droplet Hydrodynamic Electrochemistry for Water Toxicity Bioassay Based on an Electron-Transfer Mediator

Kazuto Sazawa, Ahanjiana Yeasna, Kazuharu Sugawara, Hideki Kuramitz

Subject: Environmental And Earth Sciences, Water Science And Technology Keywords: electrochemical bioassay; mediator; Escherichia coli; hydrodynamic voltammetry; antibiotics

Online: 20 June 2024 (04:43:25 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202407.0125.v1

Intraperitoneal Administration of 17-DMAG as an Effective Treatment Against Leishmania braziliensis Infection in BALB/c Mice: A Preclinical Study

Kercia P. Cruz, Antonio L. O. A. Petersen, Marina F. Amorim, Alan G. S. F. Pinho, Luana C. Palma, Diana A. S. Dantas, Mariana R. G. Silveira, Carine S. A. Silva, Ana Luiza J. Cordeiro, Izabella G. Oliveira, Gabriella B. Pita, Bianca C. A. Souza, Gilberto C. Bonfim, Claudia I. Brodskyn, Deborah B. M. Fraga, Isadora S. Lima, Maria B. R. de Santana, Helena M. P . Teixeira, Juliana P. B. Menezes, Washington L. P. Santos, Patricia S. T. Veras

Subject: Medicine And Pharmacology, Tropical Medicine Keywords: Leishmania braziliensis; Cutaneous leishmaniasis; 17-DMAG-HCL; Treatment

Online: 1 July 2024 (15:41:21 CEST)

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Preprint REVIEW | doi:10.20944/preprints202408.0881.v1

An Overview of Tools and Technologies for Anxiety and Depression Management Using AI

Adrianos Pavlopoulos, Theodoros Rachiotis, Ilias Maglogiannis

Subject: Social Sciences, Psychology Keywords: Artificial intelligence; machine learning; LLMs; depression; anxiety; mental health

Online: 13 August 2024 (17:06:46 CEST)

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This study aims to evaluate the utilization and effectiveness of artificial intelligence (AI) applications in managing symptoms of anxiety and depression. The primary objectives are to identify current AI tools, analyze their practicality and efficacy, and assess their potential benefits and risks. A comprehensive literature review was conducted using databases such as ScienceDirect, Google Scholar, PubMed, and ResearchGate, focusing on publications from the last five years. The search utilized keywords including "artificial intelligence," "applications," "mental health," "anxiety," "LLMs" and "depression". Various AI tools, including chatbots, mobile applications, wearables, virtual reality settings, and large language models (LLMs), were examined and categorized based on their functions in mental health care. The findings indicate that AI applications, including LLMs, show significant promise in symptom management, offering accessible and personalized interventions that can complement traditional mental health treatments. Tools such as AI-driven chatbots, mobile apps, and LLMs have demonstrated efficacy in reducing symptoms of anxiety and depression, improving user engagement and mental health outcomes. LLMs, in particular, have shown potential in enhancing therapeutic chatbots, diagnostic tools, and personalized treatment plans by providing immediate support and resources, thus reducing the workload on mental health professionals. However, limitations include concerns over data privacy, the potential for over-reliance on technology, and the need for human oversight to ensure comprehensive care. Ethical considerations, such as data security and the balance between AI and human interaction, were also addressed. The study concludes that while AI, including LLMs, has the potential to significantly aid mental health care, it should be used as a complement to, rather than a replacement for, human therapists. Future research should focus on enhancing data security measures, integrating AI tools with traditional therapeutic methods, and exploring the long-term effects of AI interventions on mental health. Further investigation is also needed to evaluate the effectiveness of AI applications across diverse populations and settings.

Preprint REVIEW | doi:10.20944/preprints202404.1432.v1

Evaluating the Reliability of Health Portals’ Nutrition and Supplementation Advice for Pregnant Women: A Comprehensive Review

Magdalena Skowrońska, Michał Pawłowski, Robert Milewski

Subject: Medicine And Pharmacology, Dietetics And Nutrition Keywords: pregnancy; nutrition; supplementation; health portals; Evidence Based Medicine

Online: 23 April 2024 (08:02:03 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.0244.v1

Supplementary Dam Site Selection Using GIS-Remote Sensing Approach: A Case Study of Wivenhoe Dam

Aseel Zytoon, Zahra Gharineiat, Omar Alajarmeh

Subject: Environmental And Earth Sciences, Remote Sensing Keywords: Climate Change; Flooding; Dam Surveying; GIS, DEM; Selection criteria

Online: 3 April 2024 (11:06:53 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202409.1581.v1

On the Salient Limits of Strings in Assembly Theory

Wawrzyniec Bieniawski, Piotr Masierak, Szymon Łukaszyk

Subject: Physical Sciences, Mathematical Physics Keywords: assembly theory; complexity measures; information entropy; mathematical physics

Online: 20 September 2024 (05:20:03 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202311.0053.v3

Theory of Relationships Between Spaces to Obtain Numerical Knowledge

Carlos Eduardo Ramos Cardoso

Subject: Computer Science And Mathematics, Mathematics Keywords: relationships between spaces; numerical knowledge; sense of mathematics; even and odd numbers

Online: 2 July 2024 (11:18:19 CEST)

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Preprint HYPOTHESIS | doi:10.20944/preprints202306.0807.v2

Amyloid Degradation Toxicity Hypothesis: Integrative Theory of Alzheimer’s Disease

Dmitry V. Zaretsky, Maria V. Zaretskaia

Subject: Medicine And Pharmacology, Neuroscience And Neurology Keywords: Alzheimer's disease; beta-amyloid toxicity; amyloid depositions; cellular uptake; lysosome

Online: 29 November 2023 (11:06:02 CET)

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The manuscript presents the comprehensive integrative theory of the etiology and pathogenesis of Alzheimer’s disease - the amyloid degradation toxicity hypothesis - and describes the logic that underlies it.The analysis of amyloid biomarkers and stable-isotope label kinetics (SILK) studies suggest that AD diagnosis is associated with higher cellular uptake of beta-amyloid. Uptake of beta-amyloid by cells is needed for its cytotoxicity, so the uptake rate should correlate with the rate of neurodegeneration. Also, the initial step in forming extracellular aggregates cannot occur in the interstitial fluid due to the extremely low concentration of beta-amyloid but can occur intralysosomally. Therefore, the density of extracellular aggregates should positively correlate with the rate of cellular amyloid uptake. The model, which considers that both cytotoxicity and aggregation of beta-amyloid are defined by cellular uptake, successfully reproduces the probability distribution of AD diagnosis in the population. Cellular uptake of beta-amyloid is mediated by endocytosis. Endocytosed beta-amyloid induces lysosomal permeabilization that occurs without plasma membrane damage. Lysosomal permeabilization explains ion disturbances, such as an accumulation of intracellular calcium, caused by cell exposure to extracellular beta-amyloid. Some amyloid fragments, produced from beta-amyloid by lysosomal proteases, can form membrane channels in lysosomal membranes, which are large enough to leak cathepsins to the cytoplasm. Appearance of proteases in the cytoplasm results in necrosis and/or initiation of apoptosis. If the cell survives, the damage of lysosomes leads to autophagy failure and slow recycling of mitochondria, promoting the production of reactive oxygen species and potentiating cell damage.Considering the above, the integrative theory of AD etiology and pathogenesis can be formulated. The etiology of AD is the membrane channel formation by amyloid fragments produced in lysosomes. The pathogenesis includes lysosomal permeabilization by giant membrane channels, which leak lysosomal proteases into the cytoplasm. The correlation between the density of amyloid aggregates and the probability of AD appears because the intensity of cellular uptake defines both aggregation rates in vivo and cytotoxicity of beta-amyloid.The amyloid degradation toxicity hypothesis is the integrative theory of Alzheimer’s disease (AD). It successfully interprets multiple phenomena and paradoxes associated with AD pathobiology at various levels, from molecular and cellular to biomarkers. The hypothesis explains the limitations of currently used biomarkers of AD and proposes etiology-related parameters. These parameters could be measured in humans and become novel diagnostic and prognostic clinical tools. Based on the proposed framework, we foresee the development of effective medications to treat, stall the progression of, or prevent disease development.

Preprint SHORT NOTE | doi:10.20944/preprints202310.0212.v3

Disproof of Several Recently Published Results in Ring Theory

S K Pandey

Subject: Computer Science And Mathematics, Algebra And Number Theory Keywords: ring theory; algebra; mathematics; disproof; counterexamples; involution t-clean ring; weakly tripotent ring; invo-regular ring; locally invo-regular ring; strongly 2-nil clean ring; strongly nil clean ring

Online: 6 November 2023 (10:25:33 CET)

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Preprint ARTICLE | doi:10.20944/preprints202011.0518.v1

Emergence of Lagrangian Field Theory from Self-Organized Criticality

Ervin Goldfain

Subject: Physical Sciences, Particle And Field Physics Keywords: Self-organized criticality, multifractals, Lagrangian field theory, non-equilibrium dynamics, complexity theory.

Online: 19 November 2020 (16:18:10 CET)

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Preprint ARTICLE | doi:10.20944/preprints201903.0245.v1

Convergence in Quantum Field Theory without Use of Renormalization

Biswaranjan Dikshit

Subject: Physical Sciences, Particle And Field Physics Keywords: Renormalization, Quantum Field Theory, Electron self energy, Vacuum polarization

Online: 26 March 2019 (14:07:37 CET)

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Preprint ARTICLE | doi:10.20944/preprints201812.0322.v1

A Century of Futurist Architecture: From Theory to Reality

Farhan Asim, Venu Shree

Subject: Engineering, Architecture, Building And Construction Keywords: Futuristic Architecture; Neo-futurism; Deconstructivism; Modernism; Antonio Sant’ Elia

Online: 27 December 2018 (11:31:13 CET)

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Preprint ARTICLE | doi:10.20944/preprints201805.0137.v1

The Brain, Explained: A Comprehensive Theory of Brain Function

Ari Rappoport

Subject: Biology And Life Sciences, Neuroscience And Neurology Keywords: neuroscience; thalamus; basal ganglia; cortical layers; hippocampus; cerebellum; habenula; claustrum; amygdala; inhibition; predictions; automaticity; dopamine; serotonin; acetylcholine; opioids; oxytocin; crh; glucocorticoids; cannabinoids; orexin; melanin-concentrating hormone; mirror neuron; place cells; grid cells; language; imagery; working memory; attention; consciousness; emotions

Online: 9 May 2018 (05:35:51 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201803.0073.v2

Theory of an Emerging-State Actor: the ISIS Case

Timothy Clancy

Subject: Social Sciences, Government Keywords: ISIS, ISIL, DAESH, insurgency, conflict, security, non-state actor, emerging-state actor, combat simulator, geospatial, national security.

Online: 13 March 2018 (14:37:09 CET)

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Preprint ARTICLE | doi:10.20944/preprints202203.0191.v1

Alcohol Consumption, Loneliness, Quality of Life, Social Media Usage, and General Anxiety Before and During the COVID-19 Pandemic in Singapore

Mengieng Ung, Kalista Yearn Yee Wan, Shi Yu Liu, Ying Jie Choo, Nathaniel Shan Wei Liew, Zhexuan Azure Shang, Sophie Su Hui Khoo, Wei Xuan Tay, Ruixi Lin, Siyan Yi

Subject: Medicine And Pharmacology, Psychiatry And Mental Health Keywords: COVID-19; pandemic; GAD-7; mental health; quality of life; Asia

Online: 14 March 2022 (16:20:20 CET)

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Preprint ARTICLE | doi:10.20944/preprints201909.0008.v2

Well-Posedness and Long-Time Behavior of Solutions for Two-Dimensional Navier-Stokes Equations with Infinite Delay and General Hereditary Memory

Yasi Zheng, Wenjun Liu, Yadong Liu

Subject: Computer Science And Mathematics, Algebra And Number Theory Keywords: Navier-Stokes equation; infinite delay; memory kernels

Online: 18 February 2021 (10:40:32 CET)

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Preprint REVIEW | doi:10.20944/preprints202011.0657.v2

Multiparametric Monitoring of Hypnosis and Nociception-Antinociception Balance During General Anesthesia - A New Era in Patient Safety Standards and Healthcare Management

Alexandru Florin Rogobete, Ovidiu Horea Bedreag, Marius Papurica, Sonia Elena Popovici, Lavinia Melania Bratu, Andreea Rata, Claudiu Rafael Barsac, Andra Maghiar, Dragos Nicolae Garofil, Mihai Negrea, Laura Bostangiu Petcu, Daiana Toma, Corina Maria Dumbuleu, Samir Rimawi, Dorel Sandesc

Subject: Medicine And Pharmacology, Immunology And Allergy Keywords: hypnosis; multimodal monitoring; entropy; qNOX; qCON; bispectral index; surgical plethismographic index; general anaesthesia; patient safety

Online: 25 January 2021 (17:02:57 CET)

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Preprint ARTICLE | doi:10.20944/preprints202406.0043.v1

A Proposal to Change the Leap-Second Adjustments to UTC

Judah Levine

Subject: Physical Sciences, Atomic And Molecular Physics Keywords: Coordinated Universal Time; Leap seconds; UT1; UTC

Online: 3 June 2024 (08:01:18 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202407.2056.v1

Comparison between Traditional and Innovative NMR Methods for the Analysis of Sicilian Monovarietal Extra Virgin Olive Oils: Metabolic Profile is Influenced by Micro Pedoclimatic Zones

Archimede Rotondo, Giovanni Bartolomeo, Irene Maria Spanò, Giovanna Loredana La Torre, Giuseppe Pellicane, Maria Giovanna Molinu, Nicola Culeeddu

Subject: Chemistry And Materials Science, Food Chemistry Keywords: NMR analysis; MARA‐NMR; extra‐virgin‐olive‐oil; Olea europaea; 13C‐NMR; metabolic profile; PLS‐DA

Online: 25 July 2024 (13:37:37 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202407.0368.v1

Regulated ICP-OES Detectible Elements in Utah Lake: Characterization and Discussion

Rachel Ann Valek, Kaylee Brooke Tanner, Jacob B Taggert, Rebecca Lynne Ryan, Anna Catherine Cardall, Lauren M. Woodland, Maddeline J. Tanner, Gustavious Paul Williams, A. Woodrull Miller, Robert B. Sowby

Subject: Environmental And Earth Sciences, Water Science And Technology Keywords: Utah Lake; Inductively Coupled Plasma Optical Emission Spectrometry; water quality; micronutrient; lake management; trace elements; state regulations

Online: 4 July 2024 (09:16:05 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202405.1007.v1

Development and Evaluation of a Solar Milk Pasteurizer for the Savanna Ecological Zone of West Africa

Iddrisu Ibrahim, Paul Tengey, Joseph Atia Ayariga, Junhuan Xu, Boakai K. Robertson, Olufemi S. Ajayi, James Owusu-Kwarteng

Subject: Biology And Life Sciences, Biology And Biotechnology Keywords: pasteurization; solar pasteurizer; milk treatment; coliform bacteria; pathogens

Online: 15 May 2024 (08:52:35 CEST)

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Solar pasteurization, as a means of treating milk in remote rural areas without electrical power, is based on using solar energy to thermally inactivate pathogenic microorganisms at temperatures below the boiling point to maintain or improve milk quality. A solar milk pasteurizer of flat‐plate water‐heating glass acting as the solar collector, connected to a stainless-steel cylindrical milk vat, was constructed and evaluated in Navrongo, in the tropical savanna zone of Ghana, West Africa. The novel approach taken in this project is to integrate the solar collection and heat exchanger into a single unit using materials and fabrication techniques readily available in the developing world. The vat comprises a 1.5 mm thick stainless steel cylindrical tank, a 2.2 cm wide hot water jacket, and an outer layer of 5.0 mm thick aluminium foil insulation. Hot water produced by the collector was used for pasteurizing milk. The optimum quantity of milk that this device could pasteurize under the study conditions was 8 L. The device could pasteurize raw milk to a maximum temperature of 74 °C at 14:00 h GMT. The ambient temperature during the pasteurization ranged from 30 °C to 43 °C. The microbial analysis before and after the pasteurization was done, and the result shows that the total bacteria count before pasteurization was 6.6x10⁶ log CFU/mL per unit volume, and the total bacteria count after pasteurization was 1.0x10² log CFU/mL. By acceptable standards, the total bacteria count after pasteurization is within a safe range for consumption, and coliform counts were negative. The solar milk pasteurization system is cost-effective. Hence, it is appropriate for milk producers in arid pastoral areas without electricity to adopt the solar pasteurizer as an alternative to firewood as a fuel source for milk pasteurization. This approach can potentially create a cottage industry that may also play a crucial role as a water treatment technology that will improve the health of rural populations.

Preprint ARTICLE | doi:10.20944/preprints202406.1946.v1

Investigation of the Main Operational Properties of Polymer-Based Composites with the Content of Modified Mineral Filler

Ruslan E. E. Nurlybayev, Erzhan I. Kuldeyev, Erzhan I. Kuldeyev, Zhanar O. Zhumadilova, Axaya S. Yestemessova, Yelzhan S. Orynbekov

Subject: Chemistry And Materials Science, Materials Science And Technology Keywords: acrylate binder; modified filler; adhesion; coatings; covering; porosity

Online: 27 June 2024 (16:46:04 CEST)

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The article presents the results of research work devoted to the study of composite materials on polymer binder with the content of modified mineral filler - water-dispersion paint and varnish materials on acrylic polymer with modified filler - diatomite. The aim of the study is to obtain polymer-based composites with modified diatomite (water-dispersion paint on acrylic binder) with improved performance properties. Methods: determination of porosity, adhesion, elasticity, hiding power of the control composition; determination of porosity, adhesion, elasticity, hiding power of the obtained composites with the use of modified filler; investigation of the influence of radiation in the infrared radiation (IR) region of the spectrum of the paint coating surface using FLIRB620 thermal imager. As a result of work it is noticed that modification of water dispersions by silica activated diatomite promotes elimination of the main disadvantages of materials and coatings on the basis of acrylate binder - low water resistance and low physical and mechanical characteristics, introduction of modified diatomite into water emulsion paint on acrylate basis does not lead to deterioration of the main operational characteristics of paint and varnish coatings - porosity, adhesion, elasticity and covering. When analyzing the effect of emissivity in the IR region of the spectrum of the paint coating surface, a significant effect of the quantitative content of modified diatomite on the reduction of emissivity of paint coatings in the IR region of the spectrum was established and it was shown that a significant effect of the reduction of emissivity of paint coatings in the IR region of the spectrum is provided by the introduction of modified diatomite in the amount of 40 wt.h. into the mixture. The influence of the time of full-scale tests in the investigated small range regardless of the quantitative composition of modified diatomite on the performance characteristics of the paintwork was established.

Preprint ARTICLE | doi:10.20944/preprints202406.1141.v1

FhMYB108 Regulates the Expression of Linalool Synthase Gene in Freesia hybrida and Arabidopsis

Zhongzhou Yang, Wei Jin, Qi Luo, Xiaoli Li, Yunmin Wei, Yunlong Lin

Subject: Biology And Life Sciences, Life Sciences Keywords: volatile organic compound; terpenoids; Freesia hybrida; terpene synthase; transcriptional regulation

Online: 17 June 2024 (11:33:52 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202405.0736.v1

Dimensional Accuracy and Mechanical Characterization of Inconel 625 components in Atomic Diffusion Additive Manufacturing

Tobias Rosnitschek, Catharina Stierle, Christian Orgeldinger, Armin Seynstahl, Bettina Alber-Laukant, Stephan Tremmel

Subject: Engineering, Mechanical Engineering Keywords: ADAM; material extrusion; metal additive manufacturing; infill structures

Online: 12 May 2024 (07:44:41 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.0961.v1

The Preventive Potential of the Mycelial Submerged Culture of Ophiocordyceps sinensis against Neurodegenerative Diseases and Its Possible Active Compounds

Hsien-Chi Huang, Yu-Juan Shi, Thuy-Lan-Thi Vo, Tai-Hao Hsu, Tuzz-Ying Song

Subject: Medicine And Pharmacology, Complementary And Alternative Medicine Keywords: Ophiocordyceps sinensis; neurodegenerative disease; microglial; anti-inflammatory; cytokines; submerged culture

Online: 15 April 2024 (11:29:23 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.0470.v1

From Detection to Action: A Retrospective Analysis on the Impact of Screening for Congenital Heart Disease in the NICU

Ioana Roșca, Daniela-Eugenia Popescu, Ana Maria Cristina Jura, Alina Turenschi, Cristina Filip, Alexandru Dinulescu, Andreea Teodora Constantin

Subject: Medicine And Pharmacology, Pediatrics, Perinatology And Child Health Keywords: congenital heart disease; neonatology; prenatal diagnosis; parent support; neonatal intensive care unit; pulse oximetry; screening; echocardiography

Online: 7 April 2024 (10:34:52 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.0262.v1

Evaluation of Sensitivity and Applicability of a Droplet Digital Pcr Assay for Simultaneous Detecting Pseudomonas aeruginosa and Pseudomonas fragi in Foods

Ju Huang, Ligong Zhai, Junyin Wang, Xiaotian Sun, Baoshi Wang, Zhaohui Wei

Subject: Biology And Life Sciences, Food Science And Technology Keywords: Pseudomonas aeruginosa; Pseudomonas fragi; simultaneous detection; droplet digital PCR

Online: 3 April 2024 (16:17:11 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202403.0440.v1

Partial Substitution of Chemical N with Solid Cow Manure Improved Soil Ecological Indicators and Crop Yield in a Wheat-Rice Rotation System

Jintao Yu, Chun Zhang, Xuan Wang, Hongchuan Li, Yusef Kianpoor Kalkhajeh, Hongxiang Hu

Subject: Biology And Life Sciences, Agricultural Science And Agronomy Keywords: conventional fertilization; solid cow manure; crop quality; soil nutrients; ecological risk

Online: 7 March 2024 (13:10:19 CET)

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Preprint ARTICLE | doi:10.20944/preprints201611.0081.v1

Symplectic Entropy as a Novel Measure for Complex Systems

Min Lei, Guang Meng, Wenming Zhang, Joshua Wade, Nilanjan Sarkar

Subject: Physical Sciences, Theoretical Physics Keywords: symplectic geometry; symplectic principal component analysis; symplectic entropy; complex system.

Online: 16 November 2016 (12:40:50 CET)

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Preprint ARTICLE | doi:10.20944/preprints201610.0079.v1

Experimental Study on the Hydrodynamic Influence of River Flow Confluences to the Open Channel Stage-Discharge Relationship

Xiekang Wang, Haizhou Wang, Xufeng Yan, Xingnian Liu, Huan-Feng Duan

Subject: Engineering, Civil Engineering Keywords: river confluence; stage-discharge relationship; hydrodynamic influence; backwater; flow separation

Online: 19 October 2016 (12:31:32 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202409.1329.v1

The Impact of Parental Depression, Anxiety, and Stress on Adolescents’ Mental Health and Quality of Life: The Moderating Role of Parental Rejection

Eirini Sofrona, Georgios Giannakopoulos

Subject: Medicine And Pharmacology, Psychiatry And Mental Health Keywords: children and adolescents; parental rejection; parental depression; parental anxiety; parental stress; quality of life; mental health problems

Online: 17 September 2024 (13:41:59 CEST)

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