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Preprint REVIEW | doi:10.20944/preprints202005.0448.v1

Betacoronavirus Genomes: How Genomic Information Has Been Used to Deal with past Outbreaks and the COVID-19 Pandemic

Alejandro Llanes, Carlos M. Restrepo, Zuleima Caballero, Sreekumari Rajeev, Melissa A. Kennedy, Ricardo Lleonart

Subject: Biology And Life Sciences, Virology Keywords: betacoronaviruses; genomics; SARS-CoV; MERS-CoV; SARS-CoV-2; COVID-19

Online: 27 May 2020 (08:50:46 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202409.0573.v1

Utilization of Vestibular Information for Balance Control in Children with Chiari I Malformation

Irène Stella, Philippe Perrin, Matthieu Casteran, Anthony Joud, Art Mallinson, Olivier Klein

Subject: Medicine And Pharmacology, Neuroscience And Neurology Keywords: Chiari I malformation; paediatric neurosurgery; posturography; balance

Online: 9 September 2024 (07:55:20 CEST)

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Background: Surgery for Chiari I malformation (CMI) is indicated when typical clinic-radiological features (syringomyelia, exertional headaches, sleep apnea syndrome, tetraparesis) are present. Sometimes patients have atypical complaints suggestive of otolaryngological (ENT) involvement, and it is sometimes difficult for the neurosurgeon to determine if these complaints are related to the CMI. Our aim was to describe postural control pattern in children with CMI using Computerized Dynamic Posturography. To our knowledge, this is the first study addressing postural instability in paediatric CMI patients. Methods: twenty-eight children aged 6 to 17 years with both radiologically confirmed CMI and clinical ENT complaints were included. Children were separated into 2 groups: operated and non-operated patients, basing on neurosurgical indication. Epidemiologic and posturographic results (CDP - Equitest®) were compared between both groups, as well as pre and post operatively in the group 2. Results: in Group 2 patients, significant improvement of global SOT was found after intervention. When the three sensorial aspects of postural control calculated by the system were independently assessed, the greatest improvement was in the vestibular ratio. We also observed an altered CoG pattern (“lateral deviation”) in the Group 2 patients, which significantly differed from Group 1. Lateral deviation was significantly reduced postoperatively in Group 2 patients. A correspondence between preoperative MRI and side of lateralisation on posturography was found in 4 children, but this cannot be regarded as significant due to the low number of patients. Conclusions: postural control seems to improve after surgery for CMI in children, mostly due to improvement in vestibular function. There is a correspondence between the side of lateral deviation and the side of greatest tonsillar descent on MRI and perioperatively. Further studies are needed to support these results and to confirm utility of CDP in CMI patients.

Preprint REVIEW | doi:10.20944/preprints202408.0155.v1

Research Progress into the Regulatory Mechanism of Silent Information Regulator 1 in Sepsis

Qilong Zhou, Weijie Gao, Weijin Zhang, Shu Tang, Hongxue Fu, Pengfei Pan

Subject: Medicine And Pharmacology, Emergency Medicine Keywords: silent information regulator 1; sepsis; regulatory mechanism; signaling pathway; progression

Online: 2 August 2024 (11:55:45 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202403.1463.v1

Updating Durability Models for Concrete Structures in Chlorine Environment Based on Detection Information

Hui Gu, Zhaobo Meng

Subject: Engineering, Civil Engineering Keywords: Chlorine environment; durability models; in-situ inspection information; parameter updating; probability life prediction

Online: 25 March 2024 (11:02:45 CET)

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Preprint ARTICLE | doi:10.20944/preprints202402.0356.v1

Performance Evaluation of Precise Point Positioning Based on Multiple Real-Time Augmentation Information

Mengjun Wu, Le Wang, Wei Xie, Fan Yue, Bobin Cui

Subject: Environmental And Earth Sciences, Remote Sensing Keywords: real-time augmentation; evaluation; orbit and clock offset; precise point positioning

Online: 6 February 2024 (13:20:00 CET)

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The most commonly used real-time augmentation services in China are International GNSS Service (IGS) real-time service, PPP-B2b service, and BeiDou Satellite-Based Augmentation System (BDSBAS) dual-frequency augmentation service. However, the research on the performance evaluation, comparison and application scope of these three products is still unknown and unrevealed. This article introduces methods for obtaining real-time augmentation information and real-time orbit and clock offset recovery. Based on real-time orbit and clock offset accuracy, positioning accuracy, and positioning availability, it systematically evaluates the performance of CNES, PPP-B2b, and BDSBAS augmentation information. The results indicate that the radial accuracy of CNES and PPP-B2b real-time orbit products is consistent, and the Root Mean Square (RMS) is better than 5 cm. CNES can achieve centimeter-level accuracy in both along-track and cross-track components, surpassing the decimeter-level accuracy of PPP-B2b. Both services demonstrate consistent accuracy in real-time clock offset, with PPP-B2b showing similar standard deviations (STD) of 0.16 ns for different satellites. However, for CNES, the STD of real-time clock offset varies for GPS, BDS-3 MEO, and BDS-3 IGSO satellites, with values of 0.10 ns, 0.19 ns, and 0.60 ns, respectively. The accuracy and availability of the two PPP services exhibit the same levels, with centimeter-level accuracy achieved after convergence and positioning availability exceeding 99%. Therefore, the difference between the two services in application areas depends on the acquisition of augmentation information. However, BDSBAS, which concentrates on code observations, demonstrates lower accuracy in real-time orbit and clock offset, positioning accuracy, and positioning availability compared to the other two services. Its primary application is in the aviation and maritime domains, where there is a greater need for service integrity, continuity, and reliability.

Preprint ARTICLE | doi:10.20944/preprints202401.0548.v1

Rapid Determination Method of Reinforced Concrete Column Failure Modes using Simple Structural Information

Subin Kim, Hee-Jin Hwang, Keunyeong Oh, Jiuk Shin

Subject: Engineering, Civil Engineering Keywords: Reinforced Concrete Columns; Machine-Learning; Column Failure Modes, Classification Model; Simple Column Details

Online: 8 January 2024 (06:43:22 CET)

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Preprint CONCEPT PAPER | doi:10.20944/preprints202312.1424.v2

Past Epigenetic Information Archive with Blockchain Data Architecture in a Biological Cellular Substructure

Jung In Choi

Subject: Biology And Life Sciences, Cell And Developmental Biology Keywords: epigenetic information; epigenetic modification; blockchain; cellular network; data archive; evolution; data immutability; distributed ledger; p2p communication; cellular substructure

Online: 25 December 2023 (10:26:10 CET)

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Past epigenetic information refers to the epigenetic modifications that have occurred in the past have since been updated. These modifications may no longer be present and not actively influencing on cellular functions. When past epigenetic modifications disappear, the precise records of those modifications typically may be vanish. If it is indeed true, a critical question arises: Can an organism sustain continuous survival and evolution without the information about past epigenetic modifications up to the present? It is reasonable to assume that among the information about past modifications, there could be crucial data essential for survival and evolution. If all these experiences were to vanish, rendering them unknowable in the present, it would undoubtedly pose significant challenges to survival and evolution. Therefore, the argument that such epigenetic information has been securely stored somewhere within the cell is not merely speculative but likely a factual reality.In this study, a new term “Epigenetic Archive”, is introduced in biology. It refers to a data repository that encompasses all experience data on past epigenetic modifications. The argument presented here underscores the importance of Epigenetic Archive and the need for its secure preservation. According to the argument, the information that cells experience should be continuously and securely stored, and any distortion of this information is said to be inconsistent with the principles of evolution and survival. This information is seen as evidence of a cell's successful existence up to the present, and it is emphasized that this successful record must be preserved. From this perspective, Epigenetic Archive should be designed to safely store past biological experiences and link this information securely to the present data. This study proposes that the data architecture in Epigenetic Archive is indeed akin to the principles of blockchain technology, particularly in terms of immutability and a distributed ledger securely preserving information across generations and ensuring that all cells possess consistent epigenetic information across a biological organism.The applications and implications of such an analogy of blockchain to Epigenetics could be an original contribution for future research on biology and genetics.

Preprint ARTICLE | doi:10.20944/preprints202311.1885.v1

Approach of Trajectory Generation Based on Waypoint Information for a Highly Automated Vehicle

Kirill Sviatov, Ivan Rubtsov, Aleksey Filippov, Anton Romanov

Subject: Computer Science And Mathematics, Artificial Intelligence And Machine Learning Keywords: unmanned vehicles; autonomous vehicles; navigation; agriculture; q-learning; Reeds-Shepp curves

Online: 29 November 2023 (10:52:54 CET)

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Preprint ARTICLE | doi:10.20944/preprints202310.1228.v1

Linking Climate Change information with Crop Growing Seasons in the Northwest Ethiopian Highlands

Gashaw Bimrew, Addis Aschenaki, Sisay E Debele

Subject: Environmental And Earth Sciences, Atmospheric Science And Meteorology Keywords: Rainfall; Temperature; Potential evapotranspiration; Soil water content; Climate Projection

Online: 19 October 2023 (07:02:24 CEST)

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Preprint REVIEW | doi:10.20944/preprints202307.1929.v1

Emerging Information Technologies for the Energy Management of Onboard Microgrids in Transportation Applications

Zhen Huang, Xuechun Xiao, Yuan Gao, Yonghong Xia, Tomislav Dragicevic, Patrick Wheeler

Subject: Engineering, Electrical And Electronic Engineering Keywords: onboard microgrid; intelligent transportation; energy management; artificial intelligence; digital twin; machine learning; reinforcement learning

Online: 28 July 2023 (07:35:21 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202307.1633.v1

Digital Technologies Selection under Hesitant Fuzzy Information: The Case of the Automotive Sector

Maryam Gallab, Youssef Lamrani, Hafida Bouloiz, Mario Di Nardo, Mohamed Tkiouat, Sara Jebbor, Adil Elfakir

Subject: Engineering, Industrial And Manufacturing Engineering Keywords: Industry 4.0; Digital Technologies; MCDM Approach; Hesitant fuzzy set; uncertainty management

Online: 25 July 2023 (03:12:44 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202307.0188.v1

Exploring the Role of Information Technology in Supporting Sustainability Efforts in Saudi Arabia

Ashwag Madkhali, Seedwell T.M. Sithole

Subject: Business, Economics And Management, Business And Management Keywords: Accounting; Environment; Information Technology; Innovation; Sustainability

Online: 4 July 2023 (10:10:06 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202306.1842.v1

MSTPose: Learning Enriched Visual Information with Multi-Scale Transformers for Human Pose Estimation

Chengyu Wu, Xin Wei, Shaohua Li, Ao Zhan

Subject: Computer Science And Mathematics, Artificial Intelligence And Machine Learning Keywords: human pose estimation; multi-scale transformer; coordinate attention; one-dimensional coordinate vector regression

Online: 27 June 2023 (03:11:38 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202102.0073.v1

The Impact of Feedback Information on Dynamics Performance of Production-Inventory Control Systems

Huthaifa AL-Khazraji, Colin Cole, William Guo

Subject: Engineering, Automotive Engineering Keywords: Inventory Control; Modeling; Simulation; Optimization

Online: 2 February 2021 (08:23:47 CET)

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Preprint ARTICLE | doi:10.20944/preprints202012.0291.v1

Information Technology Impact Factor Model in Life Cycle Cost Management of Construction Project

Peter Mésároš, Tomáš Mandičák, Marcela Spišáková

Subject: Engineering, Civil Engineering Keywords: information technology; construction project management; cost management; impact factor model; progressive technology; construction industry, life cycle cost management.

Online: 11 December 2020 (16:12:55 CET)

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Preprint ARTICLE | doi:10.20944/preprints202004.0368.v2

Gravity, Entanglement and Spin Possible Timeless State of the Universe

Ahmed Farag Ali

Subject: Physical Sciences, Quantum Science And Technology Keywords: gravity; hidden variables; information loss problem; completeness

Online: 22 April 2020 (06:12:30 CEST)

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Working Paper ARTICLE

Information Length as a Useful Index to Understand Variability in the Global Circulation

Eun-jin Kim, James Heseltine, Hanli Liu

Subject: Physical Sciences, Fluids And Plasmas Physics Keywords: variabilities; modeling; non-equilibrium; turbulence; gravity waves; PDFs

Online: 31 January 2020 (10:39:09 CET)

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With improved measurement and modelling technology, variability has emerged as an essential feature in non-equilibrium processes. While traditionally, mean values and variance have been heavily used, they are not appropriate in describing extreme events where a significant deviation from mean values often occurs. Furthermore, stationary Probability Density Functions (PDFs) miss crucial information about the dynamics associated with variability. It is thus critical to go beyond a traditional approach and deal with time-dependent PDFs. Here, we consider atmospheric data from the Whole Atmosphere Community Climate Model (WACCM) and calculate time-dependent PDFs and the information length from these PDFs, which is the total number of statistically different states that a system passes through in time. Time-dependent PDFs are shown to be non-Gaussian in general, and the information length calculated from these PDFs shed us a new perspective of understanding variabilities, correlation among different variables and regions. Specifically, we calculate time-dependent PDFs and information length and show that the information length tends to increase with the altitude albeit in a complex form. This tendency is more robust for flows/shears than temperature. Also, much similarity among flows and shears in the information length is found in comparison with the temperature. This means a stronger correlation among flows/shears because of a strong coupling through gravity waves in this particular WACCM model. We also find the increase of the information length with the latitude and interesting hemispheric asymmetry for flows/shears/temperature, a stronger anti-correlation (correlation) between flows/shears and temperature at a higher (low) latitude. These results also suggest the importance of high latitude/altitude in the information budge in the Earth's atmosphere, the spatial gradient of the information as a useful proxy for the transport of physical quantities.

Preprint ARTICLE | doi:10.20944/preprints201912.0227.v1

An Information Ontology for the Process Algebra Model of Non-Relativistic Quantum Mechanics

William Sulis

Subject: Physical Sciences, Mathematical Physics Keywords: information; process; process algebra; causal tapestry; process tapestry; transience; contextuality; emergence

Online: 17 December 2019 (10:07:58 CET)

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Preprint ARTICLE | doi:10.20944/preprints201808.0269.v1

Sensing Earthquake Disaster Information: A Named Entity Recognition Approach Using Twitter Collaborative Data

Aldo Hernandez-Suarez, Gabriel Sanchez-Perez, Karina Toscano-Medina, Hector Perez-Meana, Jose Portillo-Portillo, Victor Sanchez

Subject: Computer Science And Mathematics, Information Systems Keywords: social sensing; supervised learning; statistical methods; social networks; twitter; tweets; natural disaster; random forest, kernel density estimation

Online: 15 August 2018 (11:34:43 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201805.0024.v1

An Investigation on Virtual Information Modeling Acceptance Based on Project Management Knowledge Areas

Nasim Didehvar, Mohammadnabi Teymourifard, Mohammad Mojtahedi, Samad Sepasgozar

Subject: Engineering, Architecture, Building And Construction Keywords: virtual information modeling; project management knowledge areas; construction projects; communication management.

Online: 2 May 2018 (11:40:14 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202407.0964.v1

Influence of the processing conditions on the rheology and heat of decomposition of solution processed hybrid nanocomposites and implication to sustainable energy storage

Andekuba Andezai, Jude O. Iroh

Subject: Chemistry And Materials Science, Materials Science And Technology Keywords: polyimide nanocomposites; Nanographene sheets; Carbon nanotube sheets; Intrinsic viscosity; Shear thickening; Total heat of decomposition; Cyclic voltammetry; Specific capacitance; Processing temperature

Online: 11 July 2024 (11:37:09 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202408.1642.v1

Impact of First- and Second-Generation Tyrosine Kinase Inhibitors on the Development of Graft-Versus-Host Disease in Individuals with Chronic Myeloid Leukemia: A Retrospective Analysis on behalf of the Polish Adult Leukaemia Group

Ugo Giordano, Agnieszka Piekarska, Witold Prejzner, Lidia Gil, Jan Maciej Zaucha, Joanna Kujawska, Zuzanna Dybko, Krzysztof Dudek, Sebastian Giebel, Jarosław Dybko

Subject: Medicine And Pharmacology, Hematology Keywords: allogeneic hematopoietic stem cell transplantation; chronic myeloid leukaemia; tyrosine kinase inhibitors; imatinib; dasatinib; nilotinib

Online: 22 August 2024 (16:30:22 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202406.0486.v1

Same Organ, Two Cancers: Complete Analysis of Renal Cell Carcinomas and Upper Tract Urothelial Carcinomas

Sorin Vamesu, Oana Andreea Ursica, Serban Eduard Milea, Mariana Deacu, Mariana Aşchie, Anca Florentina Mitroi, Voinea Felix, Mihaela Butcaru Pundiche, Cristian Ionut Orasanu, Raluca Ioana Voda

Subject: Medicine And Pharmacology, Urology And Nephrology Keywords: renal cell carcinoma, upper tract urothelial carcinoma, perineural invasion, risk factor, hematuria

Online: 7 June 2024 (10:55:42 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202405.0406.v1

Quantitative-Qualitative Assessment of Dream Reports in Schizophrenia and Their Correlations with Illness Severity

Gianluca Ficca, Oreste De Rosa, Davide Giangrande, Tommaso Mazzei, Salvatore Marzolo, Benedetta Albinni, Alessia Coppola, Alessio Lustro, Francesca Conte

Subject: Social Sciences, Cognitive Science Keywords: Dreams; Schizophrenia; Emotion Regulation

Online: 7 May 2024 (23:48:18 CEST)

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Preprint REVIEW | doi:10.20944/preprints202408.1848.v1

Understanding Proton Magnetic Resonance Spectroscopy Neurochemical Changes using Alzheimer’s Disease Biofluid, PET, Postmortem Pathology Biomarkers and APOE Genotype

FIRAT KARA, Kejal Kantarci

Subject: Biology And Life Sciences, Neuroscience And Neurology Keywords: Alzheimer’ s disease; mild cognitive impairment; magnetic resonance spectroscopy; amyloid; tau; biofluid biomarkers; apolipoprotein ε 4

Online: 26 August 2024 (20:14:17 CEST)

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Preprint REVIEW | doi:10.20944/preprints202408.1976.v1

Bioimpedance Analysis in CKD and HF Patients: A Critical Review of Benefits, Limitations, and Future Directions

Alessandro Faragli, Edoardo La Porta, Alexander Herrmann, Francesco Paolo Lo Muzio, Luca Estienne, Stefano Geniere Nigra, Antonio Bellasi, Giacomo Deferrari, Giovanni Ricevuti, Salvatore Di Somma, Alessio Alogna

Subject: Medicine And Pharmacology, Clinical Medicine Keywords: Bioimpedance Analysis; Heart Failure; Kidney Disease; Chronic Patients; Cardiology; Nephrology; Diagnostics; Prognosis

Online: 27 August 2024 (15:47:47 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202409.1855.v1

Antimicrobial Susceptibility of Uropathogenic Escherichia coli with Analysis of Impact of Socio-Economic Factors in Low, Medium and High-Income Countries

Meher Rizvi, Maria Khan, Amina AL Jardani, Ujjala Ghoshal, Zaaima AL Jabri, Mohammad Ahanjan, Azza AL Mamari, Nawal AL Shizawi, Hiba Sami, Abdullah Balkhair, Adila Shaukat, Alwarith Nasser Salem Alkharusi, Abdulrahman Almahrouqi, Afreenish Hassan, Ajay Kumar, Amal Malehi, Amina Gul, Ashima Singh, Asma Said Hamed AL Shidhani, Areena Hoda Siddiqui, Aruna Poojary, Azza AL Rashdi, Bradley Langford, Dmytro Stepanskyi, Abbas Dolatabadi, Aisha Al Mufraji AL Mufraji, Elham Said Ahmed AL Risi, Garima Kapoor, Isabella Princess, Hatim Ali Eltahir, Hilal Al Sidairi, Kaitlyn Dougherty, Katia Iskandar, Ken Masters, Ibrahim Khalaf Hamdan AL Busaidi, Laila AL Yazidi, Mahfuza Nasrin, Mahmood Salim AL Subhi, Mallika Sengupta Mallika Sengupta, Manisha Khandait, Nada Khalfan AL Tamtami, Nada Khafan Alsiyabi, Nawal AL Kindi, Nazla Musthafa Luthfee, Neha Shreshtha, Nihal Mohamed Amur AL Riyami, Noora Hilal Ali AL Busaidi, Nupur Goel, Oksana Ishchenko, Omnia Mohamed Elnabawy Ahmed Taher, Pragnya Paramita Jena, Rajni Ekadashi, Razan Zadjali, Reba Kanungo, Sara Abolghasemi, Salima Al-maqbali, Sanjay Jaju, Sayantan Banerjee, Shadma Yaqoob, Shahnaz Sali, Shafqat Husnain Khan, Shalini Malhotra, Stephen Hughes, Sundas Shaukat, Syed Mohammed Atif, Vrushali Vishwas Patwardhan, Victorien Dougnon, Wahid Khan, Walid Wali, Zakariya AL Muharrmi, Zeeshana Basit, Jasashree Choudhury, Rachita Pravalina, Sanjeev Singh, Sarman Singh, Neelam Taneja, Raman Sardana, Pawan Kapoor, Rajeev Soman, Rashid Al Abri

Subject: Medicine And Pharmacology, Epidemiology And Infectious Diseases Keywords: community acquired UTI; Escherichia coli; antimicrobial susceptibility; Indian subcontinent; MENA; GDP; temperature

Online: 24 September 2024 (12:32:05 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202407.1153.v1

Genome-Wide Identification of AGO, DCL, and RDR Genes and Their Expression Analysis in Response to Drought Stress in Peach

Mohammad Belal, Charmaine Ntini, Cherono Sylvia, Misganaw Wassie, Mahmoud Magdy, Collins Ogutu, Mohamed Ezzat, Md Dulal Ali Mollah, Yunpeng Cao, Weihan Zhang, Elsayed Nishawy, Yuepeng Han

Subject: Biology And Life Sciences, Biology And Biotechnology Keywords: ; Prunus persica; drought; AGO; DCL; RDR; Genome-wide identification; gene expression ;

Online: 16 July 2024 (03:04:56 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202312.0738.v1

Optimization of a Low-cost Corona-DBD Plasma Wastewater Treatment System through CCD/RSM with Mechanistic and Efficiency Analysis

Yiting Xiao, Yang Tian, Yuanhang Zhan, And Jun Zhu

Subject: Environmental And Earth Sciences, Pollution Keywords: Water purification; non-thermal plasma; reactor design; advanced purification systems

Online: 11 December 2023 (16:38:11 CET)

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Preprint ARTICLE | doi:10.20944/preprints202404.1886.v1

Analysis of the Financial and Non-Financial Indicators of the Beer Sector: Italy and Spain

Núria Arimany Serrat, Andrey Felipe Sgorla

Subject: Business, Economics And Management, Business And Management Keywords: Compositional data (CoDa); financial statement analysis; financial ratios; accounting ratios; financial indicators; non-financial indicators.

Online: 29 April 2024 (05:14:22 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202408.0134.v1

Analysis of Synergistic Drivers of CO2 and NOX Emissions from Thermal Power Generating Units in Beijing-Tianjin-Hebei, 2010-2020

Yaolin Wang, Zilin Yuan, Haixu Zhang, Qinge Guan, Sheng Rao, Chunlai Jiang, Zhiguo Duan

Subject: Environmental And Earth Sciences, Environmental Science Keywords: thermal power units; CO2; NOX; synergistic drivers

Online: 2 August 2024 (10:38:36 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202306.0764.v1

Near-Infrared Spectroscopy of 2-Month Exercise Intervention Effects in Sedentary Older Adults With Diabetes and Mild Cognitive Impairment

Fei Zhao, Machiko Tomita, Anirban Dutta

Subject: Engineering, Bioengineering Keywords: type 2 diabetes mellitus; functional near-infrared spectroscopy; muscle near-infrared spectroscopy; cognitive impairment; operational modal analysis

Online: 12 June 2023 (05:03:09 CEST)

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The Global Burden of Disease Study (GBD 2019 Diseases and Injuries Collaborators) found that diabetes significantly increases the overall burden of disease, leading to a 24.4% increase in disability-adjusted life years. Persistently high glucose levels in diabetes can cause structural and functional changes in proteins throughout the body, and the accumulation of protein aggregates in the brain is associated with the progression of Alzheimer's Disease (AD).To address this burden of type 2 diabetes mellitus (T2DM), a combined aerobic and resistance exercise program was developed based on the recommendations of the American College of Sports Medicine. The prospectively registered clinical trials (https://www.clinicaltrials.gov/ct2/show/NCT04626453, https://www.clinicaltrials.gov/ct2/show/NCT04812288) involved two groups: an Intervention group of older sedentary adults with T2DM and a Control group of healthy older adults who could be either active or sedentary. The completion rate for the 2-month exercise program was high, with participants completing on an average of 89.14% of the exercise sessions. This indicated that the program was practical, feasible, and well-tolerated, even during the COVID pandemic. It was also safe, requiring minimal equipment and no supervision. The exercise instructions were easy to understand, making them suitable for older adults with cognitive decline.The near-infrared spectroscopy (NIRS) based brain and muscle oxygenation study provided evidence on brain overactivation among older adults with T2DM, supporting the compensatory theory. It also demonstrated that the 2-month combined exercise intervention effectively reduced brain overactivation and contributed to improved cognitive function. Operational modal analysis showed an exercise-related effect on the very low-frequency hemodynamic oscillations cluster, which may be associated with better vascular muscle and/or perivascular neurogenic regulation. Furthermore, we personalized the exercise duration and interval based on muscle oxygenation during physical tasks, leading to improvements in muscle oxidative capacity within just two months. This finding has practical implications for physical therapists, as they can target muscle oxygenation changes during physical tests to prescribe appropriate exercise doses for enhancing physical performance.

Preprint ARTICLE | doi:10.20944/preprints202408.1567.v1

Spatiotemporal Evolution and Tapio Decoupling Analysis of Energy-Related Carbon Emissions Using Nighttime Light Data: A Quantitative Case Study at the City Scale in Northeast China

Bin Liu, Jiehua Lv

Subject: Social Sciences, Urban Studies And Planning Keywords: energy carbon emissions; nighttime light (NTL) data; spatiotemporal evolution; Tapio decoupling analysis; Northeast China

Online: 21 August 2024 (16:58:03 CEST)

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As the world’s second-largest economy, China has undergone rapid industrialization and urbanization, leading to high energy consumption and significant carbon emissions. This development has exacerbated conflicts between human-land relations and environmental conservation, contributing to global warming and urban air pollution, both of which pose serious health risks. This study utilizes nighttime light (NTL) data from 2005 to 2019, combined with scaling techniques and statistical analysis, to estimate city-scale energy carbon emissions over a 15-year period. Our focus is on Northeast China, a traditional industrial region comprising 36 cities across three provinces, rich in natural resources but now facing severe aging challenges. We analyzed the spatial patterns of energy carbon emissions, while spatiotemporal evolution was assessed through spatial autocorrelation and dynamic changes. These dynamic changes were further evaluated using standard deviation ellipse (SDE) parameters and SLOPE values. Additionally, we examined the conflict between city-scale emissions and economic growth using the Tapio decoupling index. Our findings for the 36 cities over the 15-year period include: (1) Heilongjiang shows low emissions with a downward trend; Jilin shows overall improvement; Liaoning has high and steadily increasing emissions. (2) The global spatial autocorrelation of energy carbon emissions is significant, with a positive Moran’s I, while significant local Moran’s I clusters are concentrated in Heilongjiang and Liaoning. (3) The SDE shows the greatest changes in city-scale emissions occurred in 2015, followed by 2019, 2005, and 2010. (4) Emission growth across the 36 cities is fastest in Heilongjiang, followed by Liaoning and Jilin. (5) Tapio decoupling analysis shows overall positive decoupling in Heilongjiang, a decline in decoupling quality in Jilin, and no significant change in Liaoning. Finally, we recommend strategies to reduce emissions from the perspectives of government, industry, and residents. This research offers a quantitative foundation for achieving dual carbon goals and supports the implementation of policies focused on energy transition and sustainable urban planning.

Preprint ARTICLE | doi:10.20944/preprints202404.1198.v1

Instrumental Analysis of Aquatic Organic Pollutants and Its Association with the Spread of Multi-drug Resistant Bacteria

YUNXUAN XIE, Mohammad Elsheikh

Subject: Environmental And Earth Sciences, Oceanography Keywords: multi-drug resistant bacteria; microbial treatment; coastal organic waste; Pseudomonadale; marine microorganisms

Online: 18 April 2024 (08:10:05 CEST)

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Preprint COMMUNICATION | doi:10.20944/preprints202404.1587.v1

Effect of Substrate Temperature on Weld Track Geometry in Directed Energy Deposition: A Comprehensive Investigation and Regression Modeling of processing 316L

Stefan Gnaase, Artur Walter, Robin Rohling, Thoas Tröster

Subject: Engineering, Mechanical Engineering Keywords: additive manufacturing; direct energy deposition; laser metal deposition; DED; LMD; 316L; 1.4404

Online: 25 April 2024 (02:35:50 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202311.0609.v1

Pathogenic Variants in USH1G/SANS Alter the Protein Interaction With the Pre-RNA Processing Factors PRPF6 and PRPF31 of the Spliceosome

Jacques S. Fritze, Felizitas F. Stiehler, Uwe Wolfrum

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: splicing, U4/U6.U5 tri-snRNP, Usher syndrome, protein-protein interaction, FRET, AlphaFold2, in silico structure predictions,

Online: 9 November 2023 (07:25:05 CET)

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Preprint REVIEW | doi:10.20944/preprints202304.1274.v1

Opportunities in Grain Processing, through the Use of Waste and By-Products: An Overview of Sustainable Valorization in the Food Industry

Cristina- Anca Danciu, Anca Tulbure, Mirela-Aurora Stanciu, Iuliana Antonie, Ciprian Capatana

Subject: Biology And Life Sciences, Food Science And Technology Keywords: grain waste; grain by-products; valorization; circular economy

Online: 30 April 2023 (11:05:57 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202106.0016.v2

A LabVIEW Instrument Aimed for the Research on Brain-Computer Interface by Enabling the Acquisition, Processing, and the Neural Networks based Classification of the Raw EEG Signal Detected by the Embedded NeuroSky Biosensor

Oana Andreea Rușanu

Subject: Computer Science And Mathematics, Software Keywords: brain-computer interface; EEG signal; artificial neural networks, LabVIEW application; features extraction; eye-blinks detection; EEG headset

Online: 4 January 2022 (17:56:46 CET)

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Preprint ARTICLE | doi:10.20944/preprints202008.0322.v1

Transporter Associated with Antigen Processing 1 (TAP1) as a Potential Biomarker for Breast, Lung, Liver and Ovarian Cancer using Health Informatics

Anika Tabassum, Md. Nazmus Samdani, Tarak Chandra Dhali, Rahat Alam, Foysal Ahammad, Abdus Samad, Tomasz M. Karpiński

Subject: Medicine And Pharmacology, Oncology And Oncogenics Keywords: TAP1; transcriptional expression; methylation analysis; survival analysis; co-expression; pathway analysis; health informatics

Online: 14 August 2020 (11:17:29 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202409.0106.v1

Neuroergonomic Attention Assessment in Safety-Critical Tasks: EEG Indices and Subjective Metrics Validation in a Novel Task-Embedded Reaction Time Paradigm

Bojana Bjegojević, Miloš Pušica, Gabriele Gianini, Ivan Gligorijević, Samuel Cromie, Maria Chiara Leva

Subject: Biology And Life Sciences, Neuroscience And Neurology Keywords: attention; neuroergonomics; EEG; engagement index; beta/alpha ratio; reaction time; coefficient of variation; attention ratings; MATB-II; safety-critical tasks

Online: 2 September 2024 (18:06:22 CEST)

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Preprint REVIEW | doi:10.20944/preprints202407.2281.v1

Phytoremediation of Mercury Contamination: Bibliometric Analysis

Lina M. Mosquera, Diego Paredes Cuervo, Ana M. López, Carlos A. Arias, Pedro N. Carvalho

Subject: Environmental And Earth Sciences, Environmental Science Keywords: bibliometrix; bibliometric analysis; mercury; phytoremediation; VOSviewer

Online: 29 July 2024 (10:21:46 CEST)

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Preprint REVIEW | doi:10.20944/preprints202104.0665.v3

Maternal Supply of Both Arachidonic and Docosahexaenoic Acids is Required for Optimal Neurodevelopment

Sanjay Basak, Rahul Mallick, Antara Banerjee, Surajit Pathak, Asim K. Duttaroy

Subject: Biology And Life Sciences, Neuroscience And Neurology Keywords: Arachidonic acid, 20:4n-6; Brain; Docosahexaenoic acid, 22:6n-3; Fetus; Maternal diet; Cognitive; Infants; Neurodevelopment; Neurogenesis

Online: 14 June 2021 (14:54:08 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202403.0925.v1

Efficient Eye State Detection for Driver Fatigue Monitoring Using Optimized YOLOv7-Tiny

Gwo-Ching Chang, Bo-Han Zeng, Shih-Chiang Lin

Subject: Computer Science And Mathematics, Artificial Intelligence And Machine Learning Keywords: Eye State Detection; Driver Fatigue Monitoring; YOLOv7-tiny; Structured Pruning; Neural Network Optimization

Online: 15 March 2024 (19:10:52 CET)

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Preprint REVIEW | doi:10.20944/preprints202006.0050.v1

Competitive Neurocognitive Functions Can Tell Us What to Learn and When: In Schools and Beyond

Dezso Nemeth, Kate Schipper, Claire Pleche, Karolina Janacsek

Subject: Social Sciences, Behavior Sciences Keywords: competitive learning and memory functions; cognitive development; basal ganglia; medial temporal lobe; prefrontal cortex; model-based learning; model-free learning

Online: 5 June 2020 (14:10:15 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202311.1074.v1

Mining and Mineral Processing Journals in the WoS and Their Rankings When Merging SCIEx and ESCI Databases—Case Study Based on the JCR 2022 Data

Tomislav Korman, Tomislav Malvić, Vasyl Lozynskyi, Zlatko Briševac, Zoran Kovač, Lidia Hrnčević, Krešimir Pavlić

Subject: Engineering, Mining And Mineral Processing Keywords: Mining and Mineral Processing journals; WoS; SCIEx; ESCI; ranking

Online: 16 November 2023 (09:43:59 CET)

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Preprint ARTICLE | doi:10.20944/preprints202406.1859.v1

A natural language processing model for the development of an Italian-language chatbot for Public Administration

Antonio Piizzi, Donatello Vavallo, Gaetano Lazzo, Saverio Dimola, Elvira Zazzera

Subject: Computer Science And Mathematics, Artificial Intelligence And Machine Learning Keywords: natural language processing; chatbot; BERT; Transformer; Italian language

Online: 26 June 2024 (11:19:54 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202402.1602.v1

Evaluation of the Mechanical Behavior of Asphaltic Mixtures Utilizing Residue of the Processing of Iron Ore

Antonio Carlos Rodrigues Guimarães, Márcio Leandro Alves de Arêdes, Carmen Dias Castro, Lisley Madeira Coelho

Subject: Engineering, Civil Engineering Keywords: Residues; Marshall dosage; mixtures; pavements

Online: 7 March 2024 (01:41:50 CET)

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Preprint ARTICLE | doi:10.20944/preprints202306.1914.v1

Additive Manufacture of PLLA Scaffolds Reinforced with Graphene Oxide Nano-particles via Digital Light Processing (DLP)

Omid Kordi, Amir Hossein Behravesh, Sadegh Hasannia, Seyyed Kaveh Hedayati, Majid Pourghayoumi, Mohammad Mazdi, Iman Ghaderi

Subject: Engineering, Industrial And Manufacturing Engineering Keywords: Additive Manufacturing; Tissue Engineering; DLP; Graphene Oxide; PLLA

Online: 27 June 2023 (13:03:50 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202306.0086.v1

Development of a Two- Stage Hydrometallurgical Technology for Processing Gold-Antimony Concentrate from the Olimpiadinskoe Deposit

Rostislav Rusalev, Denis Rogozhnikov, Oleg Dizer, Dmitry Golovkin, Kirill Karimov

Subject: Chemistry And Materials Science, Metals, Alloys And Metallurgy Keywords: antimony; arsenic; gold leaching; nitric acid; refractory gold ores; leaching

Online: 1 June 2023 (12:22:40 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202210.0238.v1

From Twitter to Aso-Rock: A Natural Language Processing Spotlight for Understanding Nigeria 2023 Presidential Election

Olusola Olabanjo, Ashiribo Wusu, Mauton Asokere, Rebecca Padonu, Olufemi Olabanjo, Oluwafolake Ojo, Oseni Afisi, Olusegun Folorunso, Manuel Mazzara, Benjamin Aribisala

Subject: Computer Science And Mathematics, Artificial Intelligence And Machine Learning Keywords: NLP; NLU; Twitter; Sentiment Analysis; Opinion Mining; Nigeria; Election; Machine Learning; BERT; LSTM; SVM

Online: 17 October 2022 (12:01:42 CEST)

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Introduction: Social media platforms such as Facebook, LinkedIn, Twitter, among others have been used as a tool for staging protests, opinion polls, campaign strategy, medium of agitation and a place of interest expression especially during elections. Past studies have established people’s opinion elections using social media posts. The advent of state-of-the-art algorithms for unstructured text processing implies tremendous progress in natural language processing and understanding. Aim: In this work, a Natural Language framework is designed to understand Nigeria 2023 presidential election based on public opinion using Twitter dataset. Methods: Raw datasets concerning discourse around Nigeria 2023 elections from Twitter of 2,059,113 18 dimensions were collected. Sentiment analysis was performed on the preprocessed dataset using three different machine learning models namely: Long Short-Term Memory (LSTM) Recurrent Neural Network, Bidirectional Encoder Representations from Transformers (BERT) and Linear Support Vector Classifier (LSVC) models. Personal tweet analysis of the three candidates provided insight on their campaign strategies and personalities while public tweet analysis established the public’s opinion about them. The performance of the models was also compared using accuracy, recall, false positive rate, precision and F-measure. Results: LSTM model gave an accuracy, precision, recall, AUC and f-measure of 88%, 82.7%, 87.2% , 87.6% and 82.9% respectively; the BERT model gave an accuracy, precision, recall, AUC and f-measure of 94%, 88.5%, 92.5%, 94.7% and 91.7% respectively while the LSVC model gave an accuracy, precision, recall, AUC and f-measure of 73%, 81.4%, 76.4%, 81.2% and 79.2% respectively. Conclusion: The experimental results show that sentiment analysis and other Natural Language Processing tasks can aid in the understanding of the social media space. Results also revealed the leverage of each aspirant towards winning the election. We conclude that sentiment analysis can form a general basis for generating insights for election and modeling election outcomes.

Preprint ARTICLE | doi:10.20944/preprints202206.0321.v1

Coffee Leaf Tea from El Salvador: On-site Production Considering Influences of Processing on Chemical Composition

Marc C. Steger, Marina Rigling, Patrik Blumenthal, Valerie Segatz, Andrès Quintanilla-Belucci, Julia M. Beisel, Jörg Rieke-Zapp, Steffen Schwarz, Dirk W. Lachenmeier, Yanyan Zhang

Subject: Chemistry And Materials Science, Food Chemistry Keywords: coffee leaf tea; novel food; coffee by-products; Coffea arabica; caffeine; epigallocatechin gallate

Online: 23 June 2022 (09:22:46 CEST)

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Preprint REVIEW | doi:10.20944/preprints202009.0315.v1

Crumb Rubber as a Secondary Raw Material from Waste Rubber: A Short Review of Processing Methods

Vjaceslavs Lapkovskis, Viktors Mironovs, Andrei Kasperovich, Vadim Myadelets, Dmitri Goljandin

Subject: Engineering, Industrial And Manufacturing Engineering Keywords: rubber; environmental sustainability; end-of-life tires; critical raw materials; rubber processing; disintegrator; reclaiming; devulcanisation; ozone cutting; grinding; composite material

Online: 14 September 2020 (00:29:25 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202003.0069.v1

Chemosensory Event-related Potentials in 3M Syndrome Infants: An Early Biomarker Based on EEG Signal Processing

Sara Invitto, Alberto Grasso, Dario Domenico Lofrumento, Vincenzo Ciccarese, Pasquale Paladini, Angela Paladini, Raffaella Marulli, Vilfredo De Pascalis, Matteo Polsinelli, Giuseppe Placidi

Subject: Social Sciences, Cognitive Science Keywords: CSERP; OERP; EEG; Spectra power; 3M syndrome; rare disease

Online: 4 March 2020 (14:56:14 CET)

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Preprint ARTICLE | doi:10.20944/preprints202003.0067.v1

Chemosensory Event-related Potentials in 3M Syndrome Infants: An early Biomarker Based on EEG Signal Processing

Sara Invitto, Alberto Grasso, Dario Domenico Lofrumento, Vincenzo Ciccarese, Angela Paladini, Pasquale Paladini, Raffaella Marulli, Vilfredo De Pascalis, Matteo Polsinelli, Giuseppe Placidi

Subject: Social Sciences, Cognitive Science Keywords: CSERP; OERP; EEG; spectra power; olfactory system; 3M syndrome; rare disease

Online: 4 March 2020 (11:38:24 CET)

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Preprint ARTICLE | doi:10.20944/preprints202403.0308.v1

Emulsion Liquid Membranes Based on Os–NP/n–decanol or n–dodecanol Nanodispersions for p–Nitrophenol Reduction

Andreia Pîrțac, Aurelia Cristina Nechifor, Szidonia-Katalin Tanczos, Ovidiu Cristian Oprea, Alexandra Raluca Grosu, Cristian Matei, Vlad-Alexandru Grosu, Bogdan Stefan Vasile, Paul Constantin Albu, Gheorghe Nechifor

Subject: Chemistry And Materials Science, Applied Chemistry Keywords: Osmium; Osmium nanoparticle; osmium reduction; p– nitrophenol reduction; nanodispersion; liquid membranes; emulsion liquid membranes; undecylenic acid; n– dodecanol; n– decanol

Online: 6 March 2024 (10:57:10 CET)

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Materials based on platinum metals with very good catalytic activity were tested in the reduction of p–nitrophenol (pNP) to p–aminophenol (pAP). The majority of presented catalytic materials are based on the adsorption of p–nitrophenol on the surface of the catalyst simultaneously with molecular hydrogen, coming from sodium borohydride in an aqueous medium, which reduces it. In the present paper, a catalytic material based on osmium dispersed in n–decanol or n–dodecanol is presented, which also works as an emulsion membrane, for the absorption of p–nitrophenol and molecular hydrogen at the n–alcohol aqueous solution interface. The hydrogenation of p–nitrophenol is carried out in a reaction and separation column in which the acid receiving phase emulsion is dispersed in the osmium nanodispersion, in n–alcohols. This emulsion circulates from the base of the column to its upper part in co-current or counter-current with the source phase consisting of p–nitrophenol and sodium borohydride. Experiments show that the circulation of counter-current phases is superior to that in co-current, and the emulsion based on n–decanol is more efficient than the one based on n–dodecanol. The increase in the pH difference between the source and receiving phases leads to the increase in the conversion of p–nitrophenol to p–aminophenol. The efficiency of separation of the reaction product in the receiving phase is lower than the conversion at the same operating time. The apparent catalytic rate constant (kapp) of the new catalytic material based on the emulsion membrane with nanodispersion of osmium nanoparticles (0.1×10−3 for n–dodecanol and 0.9×10−3 for n-decanol) is lower by an order of magnitude compared to those based on adsorption on catalysts from platinum metal group. The advantage of the tested membrane catalytic material is that it extracts p–aminophenol in the acid receiving phase. The paper proposes a mechanism of the studied reduction system.

Preprint ARTICLE | doi:10.20944/preprints202408.0577.v1

Integrating Extended Reality (XR) and Advanced ICT into Therapeutic Practices for Impaired and Socially Isolated Individuals: The Role of Healthcare Professionals in Leveraging XR for Remote Artistic and Recreational Activities

Chiara Barchielli, Sara Jayousi, Sara Guarducci, Leonardo Capanni, Giovanni Serafini, Monica Serrano, Marco Alaimo, Paolo Zoppi, Lorenzo Mucchi

Subject: Public Health And Healthcare, Public, Environmental And Occupational Health Keywords: Extended reality (EX); Therapeutic practices; Nurses; Physiotherapists; Recreational activities; Accessibility

Online: 8 August 2024 (08:42:16 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202409.0828.v1

Development and Validation of the Short form of the Joint Assessment of Equilibrium and Neuromotor Status Scale (JAEN-10)

Ana Belén Peinado-Rubia, María Catalina Osuna-Pérez, David Núñez-Fuentes, Daniel Rodríguez-Almagro, Noelia Zagalaz-Anula, Rafael Lomas-Vega

Subject: Public Health And Healthcare, Physical Therapy, Sports Therapy And Rehabilitation Keywords: balance control; chronic fatigue syndrome; disability evaluation; dizziness; fibromyalgia

Online: 11 September 2024 (04:24:02 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202401.0936.v1

Differentiating Pressure Ulcer Risk Levels Using Decision Trees Based on Interpretable Indicators: A Practical Approach for Nursing Care

Eugenio Vera-Salmerón, Carmen Dominguez-Nogueira, José A. Sáez, José L. Romero-Béjar, Emilio Mota-Romero

Subject: Public Health And Healthcare, Nursing Keywords: pressure ulcers; risk level; decision trees; nursing care; preventive measures

Online: 12 January 2024 (07:21:52 CET)

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Preprint ARTICLE | doi:10.20944/preprints202307.0234.v1

Energy Efficient Solutions: A Multi Criteria Decision Aid Tool to Achieve the Targets of the European EPDB Directive

Fabrizio Cumo, Elisa Pennacchia, Claudia Zylka

Subject: Engineering, Architecture, Building And Construction Keywords: energy requalification; standardized efficiency solutions; cost-benefit analysis; existing building stock; building energy performance

Online: 4 July 2023 (12:51:11 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201908.0079.v1

Emergency Service Provision using a Novel Hybrid SOM-Spiral STC Model for Group Decision Support Under Dynamic Uncertainty

Hai Van Pham, Philip Moore

Subject: Physical Sciences, Applied Physics Keywords: self organizing maps; fuzzy rules; emergency planning and management; group decision support; autonomous robot control; smart-environments

Online: 6 August 2019 (12:53:49 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202104.0532.v3

Examining the Role of the Noradrenergic Locus Coeruleus for 2 Predicting Attention and Brain Maintenance in Healthy Old Age 3 and Disease: An MRI Structural Study for the Alzheimer’s Disease 4 Neuroimaging Initiative

Emanuele Raffaele Giuliano Plini, Erik O'Hanlon, Rory Boyle, Francesca Sibilia, Gaia Rikhye, Joanne Kenney, Robert Whelan, Michael Christopher Melnychuk, Ian Hamilton Robertson, Paul Michael Dockree

Subject: Social Sciences, Psychology Keywords: Locus Coeruleus; Reserve; Brain Age; Visual Attention; Alzheimer’s Disease; Mild Cognitive Impairment; normal Aging; Neuroimaging; Voxel Based Morphometry

Online: 21 June 2021 (11:41:40 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202408.1924.v1

Analysis of Road Roughness and Driver’s Comfort in ‘Long-Haul’ Road Transportation Using a Random Forest Approach

O.O. Ajayi, Anish M. Kurien, K. Djouani, L. Dieng

Subject: Computer Science And Mathematics, Artificial Intelligence And Machine Learning Keywords: road roughness; driver’ s comfort; random forest; long-haul; transportation; probe vehicle; correlation

Online: 27 August 2024 (05:36:12 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201610.0013.v1

Analysis of Drought Characteristics using Time Series of Modified SPEI in South Korea from 1981 to 2010

Seungjong Bae, Sang-Hyun Lee, Seung-Hwan Yoo, Taegon Kim

Subject: Engineering, Civil Engineering Keywords: drought; SPEI; evapotranspiration; Thornthwaite; FAO Penman-Monteith

Online: 6 October 2016 (13:04:49 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202405.1501.v1

X-ray Microtomography Analysis of Integrated Crop-Livestock Production Impact on Soil Pore Architecture

José V. Gaspareto, Luiz Fernando Pires

Subject: Environmental And Earth Sciences, Soil Science Keywords: Computed tomography; Image analysis; Minimum tillage; No-tillage; Soil structure; Soil management; Soil porous structure

Online: 23 May 2024 (07:35:24 CEST)

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Preprint REVIEW | doi:10.20944/preprints202403.1485.v1

Review of Fourth-Order Maximum Entropy Based Predictive Modelling and Illustrative Application to a Nuclear Reactor Benchmark. I. Typical High-Order Sensitivity and Uncertainty Analysis

Dan Gabriel Cacuci, Ruixian Fang

Subject: Physical Sciences, Applied Physics Keywords: predictive modeling; sensitivity analysis; uncertainty quantification; data assimilation; model calibration; reducing predicted uncertainties

Online: 25 March 2024 (13:31:57 CET)

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This work (in two parts) will review the recently developed predictive modeling methodology called “4th-BERRU-PM” and its applicability to energy systems as exemplified by an illustrative application to the Polyethylene-Reflected Plutonium (acronym: PERP) OECD/NEA reactor physics benchmark. The acronym 4th-BERRU-PM designates the “Fourth-Order Best-Estimate Results with Reduced Uncertainties Predictive Modeling” methodology, which yields best-estimate results with reduced uncertainties for the first fourth-order moments (mean values, covariance, skewness, and kurtosis) of the optimally predicted posterior distribution of model results and calibrated model parameters. The 4th-BERRU-PM uses the Maximum Entropy (MaxEnt) principle to incorporate fourth-order experimental and computational information, including fourth (and higher) order sensitivities of computed model responses to model parameters, thus incorporating, as particular cases, the results previously predicted by the second-order predictive modeling methodology 2nd-BERRU-PM, and vastly generalizing the results produced by extant data assimilation and data adjustment procedures. The 4th-BERRU-PM methodology encompasses the scopes of high-order sensitivity analysis (SA), uncertainty quantification (UQ), data assimilation (DA) and model calibration (MC). The application of the 4th-BERRU-PM methodology to energy systems is illustrated by means of the above-mentioned OECD/NEA reactor physics benchmark, which is modeled using the neutron transport Boltzmann equation involving 21976 imprecisely known parameters, the solution of which is representative of “large-scale computations.” The model result (“response”) of interest is the leakage of neutrons through the outer surface of this spherical benchmark, which can be computed numerically and measured experimentally. Part 1 of this work illustrates the impact of high-order sensitivities, in conjunction with parameter standard deviations of various magnitudes, on the determination of the expected value and variance of the computed response in terms of the first four moments of the distribution of the uncertain model parameters. Part 2 of this work will illustrate the capabilities of the 4th-BERRU-PM methodology for combining computational and experimental information, up to and including forth-order sensitivities and distributional moments, for producing best-estimate values for the predicted responses and model parameters while reducing their accompanying uncertainties.

Preprint ARTICLE | doi:10.20944/preprints202409.2177.v1

An Objective Handling Qualities Assessment Framework of Electric Vertical Takeoff and Landing

Yuhan Li, Shuguang Zhang, Yibing Wu, Sharina Kimura, Michael Zintl, Florian Holzapfel

Subject: Aerospace Engineering, Engineering Keywords: Eye metrics; handling qualities; eVTOL; Urban air mobility; aircraft design; LSTM

Online: 27 September 2024 (12:31:04 CEST)

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Preprint CASE REPORT | doi:10.20944/preprints202409.1884.v1

Engineering Motivation into an Instructional Design Skill-Strength Assessment and Mentoring System

Hazzan Olusegun Mohammed

Subject: Social Sciences, Education Keywords: instructional design (ID); competency development; motivation; user-centered design (UCD)

Online: 24 September 2024 (10:12:11 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202409.0976.v1

In Vitro Quality Assessment of Glibenclamide Tablets: Reference, Generic and Similar Drugs

Bruna Serio, Juliana Yzze, Suellen Rosa

Subject: Medicine And Pharmacology, Pharmacy Keywords: Glibenclamide; diabetes mellitus; quality control; drug; in vitro; pharmacopoeia

Online: 12 September 2024 (11:25:00 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202407.1066.v1

Development and Performance Assessment of Low-Cost Sensors for Pollutants Concentration Measurement

Luigi Russi, Paolo Guidorzi, Giovanni Semprini, Arianna Trentini, Beatrice Pulvirenti

Subject: Environmental And Earth Sciences, Pollution Keywords: air quality; low cost sensors; sensor validation; pollutant concentration measurement

Online: 14 July 2024 (05:30:09 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202407.0504.v1

Assessment and Performance Mechanism Evaluation of Non-Structural Concrete Incorporating Waste Materials

Nuha S. Mashaan, Appuwa De Silva

Subject: Engineering, Civil Engineering Keywords: Waste plastic; Tyre materials; Waste; Non-structural concrete; Mechanical properties; Sustainability; LCA

Online: 5 July 2024 (08:37:52 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202405.0364.v1

Process Synthesis, Design and Techno-Economic Assessment of Bio-Succinic Acid Production

Georgios Melitos, Nikiforos Misailidis, Demetri Petrides, Michael C. Georgiadis

Subject: Engineering, Bioengineering Keywords: succinic acid; fermentation; bioprocess modelling; techno-economic assessment; optimization

Online: 7 May 2024 (10:43:59 CEST)

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Preprint REVIEW | doi:10.20944/preprints202401.1068.v1

The Assessment of the Role of Parks and Botanical Gardens in Ethiopia

Gudeta Chalchisa Diribsa

Subject: Biology And Life Sciences, Ecology, Evolution, Behavior And Systematics Keywords: Parks; Botanica garden

Online: 15 January 2024 (10:27:14 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.1212.v1

Spectrophotometric and Chromatographic Assessment of Total Flavonoids Content in Rhodendron Tomentosum Extracts

Halyna Kukhtenko, Nataliia Bevz, Oleksandr Kukhtenko, Izabela Jasicka-Misiak

Subject: Medicine And Pharmacology, Pharmacy Keywords: Rhododendron tomentosum; Ledum palustre; Wild rosemary; Rutin; Hyperoside; Quercetin; Chlorogenic acid; Aluminum chloride; UV-Vis; HPTLC

Online: 18 December 2023 (10:19:01 CET)

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Preprint ARTICLE | doi:10.20944/preprints202311.1160.v1

Wildfire-Induced Risk Assessment to Enable Resilient and Sustainable Electric Power Grid

Srikar Kovvuri, Paroma Chatterjee, Sagnik Basumallik, Anurag Srivastava

Subject: Engineering, Electrical And Electronic Engineering Keywords: Power Grid; Principal Component Analysis; Resilience; Risk Assessment; Wildfire

Online: 17 November 2023 (11:51:05 CET)

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Preprint ARTICLE | doi:10.20944/preprints202309.2065.v1

Assessment of Joinability in Additive Manufactured Interlocking Structure with Experiment and Simulation

Se-hun Kwon, Hak-Sung Lee, Ye-rim Kim, Eun-ah Kim, Joon Phil Choi, Taeho Ha, Soonho Won, Jong Bae Jeon

Subject: Engineering, Metallurgy And Metallurgical Engineering Keywords: additive manufacturing; interlocking structure; Design for Additive Manufacturing (DfAM); Netfabb Local Simulation

Online: 29 September 2023 (08:39:31 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1875.v1

Material Selection and Assessment of Electric Two-wheeler Battery Enclosure: Structural Study

Ramesh Kumar Chidambaram, Prithvi Raj Pedapati, P. Rajesh Kanna, Dawid Taler, Tomasz Sobota, Jan Taler

Subject: Engineering, Energy And Fuel Technology Keywords: Battery enclosure; electric two-wheeler; structural analysis; material selection; failure analysis.

Online: 28 September 2023 (05:02:07 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.0661.v1

Quality Assessment of Biogas-Producing Macroalgae from Azov Sea and Šventoji River

Alvydas Zagorskis, Akvilė Gotovskienė, Vladimir Monin

Subject: Environmental And Earth Sciences, Environmental Science Keywords: biogas; cattle manure; energy potential; macroalgae; methane

Online: 11 September 2023 (11:19:41 CEST)

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Preprint REVIEW | doi:10.20944/preprints202307.0803.v1

The Trend of Solar Energy Utilization and Its Offshore Assessment in Nigeria

Wasiu Olalekan Idris, Mohd Zamri Ibrahim, Aliashim Alibani

Subject: Engineering, Energy And Fuel Technology Keywords: solar PV system; renewable energy system; solar radiation; net present value; cost of electricity

Online: 12 July 2023 (11:44:28 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202307.0223.v1

Static Liquefaction Assessment Combining Shear Wave Velocity, Peak Strength and Soil Grading

Marisa Soares, António Viana da Fonseca, Cristiana Ferreira, Sara Rios

Subject: Engineering, Civil Engineering Keywords: liquefaction; shear wave velocity; peak undrained deviatoric stress; soil grading; coefficient of uniformity

Online: 5 July 2023 (02:37:56 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202306.1939.v1

Marine PET Hydrolase (PET2): Assessment of Terephthalate- and Indole-Based Polyesters Depolymerization

Paula Wagner-Egea, Lucía Aristizábal-Lanza, Cecilia Tullberg, Ping Wang, Katja Bernfur, Carl Grey, Baozhong Zhang, Javier A. Linares-Pastén

Subject: Biology And Life Sciences, Biology And Biotechnology Keywords: plastic biodegradation; marine PET hydrolase; enzymatic degradation; indole-based polyesters; PETase; PET.

Online: 27 June 2023 (16:24:19 CEST)

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Preprint REVIEW | doi:10.20944/preprints202304.0422.v1

Assessment and management of Heart Failure in Patients with Chronic Kidney Disease

Andrea Igoren Guaricci, Francesca Sturdà, Roberto Russo, Paolo Basile, Andrea Baggiano, Saima Mushtaq, Laura Fusini, Fabio Fazzari, Fulvio Bertrandino, Francesco Monitillo, Maria Cristina Carella, Marco Simonini, Gianluca Pontone, Marco Matteo Ciccone, Giuseppe Grandaliano, Giuseppe Vezzoli, Francesco Pesce

Subject: Medicine And Pharmacology, Cardiac And Cardiovascular Systems Keywords: heart failure; kidney disease; multidisciplinary assessment; personalized treatment

Online: 17 April 2023 (07:27:32 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202301.0080.v1

Validity and Reliability of the 23-Item Preterm Birth Risk Assessment Scale

Jeung-Im Kim

Subject: Medicine And Pharmacology, Obstetrics And Gynaecology Keywords: Factor Analysis, Statistical; Premature birth; Psychometrics; Scale development

Online: 4 January 2023 (11:41:59 CET)

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Preprint ARTICLE | doi:10.20944/preprints202107.0578.v1

Assessment of a Nano-Docetaxel Combined Treatment for Head and Neck Cancer

Gee Young Lee, Mohamed Mubasher, Tamra S. McKenzie, Nicole C. Schmitt, Merry E. Sebelik, Carrie E. Flanagan, Maya B. Cothran, Hadiyah-Nicole Green

Subject: Medicine And Pharmacology, Immunology And Allergy Keywords: docetaxel; combination therapy; nanoparticles; head and neck squamous cell carcinoma; oncology; therapies

Online: 26 July 2021 (14:04:49 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202107.0015.v1

Progress in Life Cycle Impact Assessment: Water Vapor Emissions and Respiratory Inorganics

Anders Andrae

Subject: Environmental And Earth Sciences, Ecology Keywords: characterization; life cycle assessment; life cycle impact assessment; normalization; particulate matter; respiratory inorganics; water vapor

Online: 1 July 2021 (11:16:42 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202104.0740.v1

Quantitative Coastal Resilience Assessment Framework under Climate Change and Sea Level Rise

Tao Wu

Subject: Engineering, Control And Systems Engineering Keywords: coastal resilience; climate change; indicators; social-ecological system

Online: 28 April 2021 (10:18:36 CEST)

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Working Paper ARTICLE

Probabilistic and risk-informed life extension assessment of wind turbines structural components

Jannie Sønderkær Nielsen, Lindsay Miller-Branovacki, Rupp Carriveau

Subject: Engineering, Civil Engineering Keywords: life extension; wind turbines; end-of-life issues; probabilistic modelling; economic optimization; fatigue; risk; remaining useful life

Online: 18 January 2021 (15:02:18 CET)

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Preprint ARTICLE | doi:10.20944/preprints202011.0600.v1

An Assessment of Urban Development and Control Mechanisms in Selected Nigerian Cities

Barnabas W. Qurix, Lawrence C. Edomwonyi-Otu, Danjuma Jise

Subject: Business, Economics And Management, Accounting And Taxation Keywords: development controls; physical planning; regulations; cities; urban development; polarization; infrastructural deficit; Kaduna; Abuja; Lagos

Online: 24 November 2020 (08:09:30 CET)

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Preprint ARTICLE | doi:10.20944/preprints202009.0404.v1

DeepSOCIAL: Social Distancing Monitoring and Infection Risk Assessment in COVID-19 Pandemic

Mahdi Rezaei, Mohsen Azarmi

Subject: Computer Science And Mathematics, Computer Science Keywords: Social Distancing; COVID-19; Human Detection and Tracking; Distance Estimation, Deep Convolutional Neural Networks; Crowd Monitoring, Inverse Perspective Mapping

Online: 17 September 2020 (11:57:01 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201906.0019.v2

Mathematical Basis for the Assessment of Antibiotic Resistance and Administrative Counter-Strategies

Hans H. Diebner, Anna Kather, Ingo Roeder, Katja de With

Subject: Biology And Life Sciences, Immunology And Microbiology Keywords: antibiotic cycling; antibiotic mixing; antibiotic resistance; diversity; entropy; heterogeneity

Online: 27 August 2020 (08:03:07 CEST)

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Diversity as well as temporal and spatial changes of the proportional abundances of different antibiotics (cycling, mixing or combinations thereof) have been hypothesised to be an effective administrative control strategy in hospitals to reduce the prevalence of antibiotic-resistant pathogens in nosocomial or community-acquired infections. However, a rigorous assessment of the efficacy of these control strategies is lacking. The main purpose here is to present a mathematical framework for the assessment of control stategies from a processual stance. To this end, we adopt diverse measures of heterogeneity and diversity of proportional abundances based on the concept of entropy from other fields and adapt them to the needs in assessing the impact of variations in antibiotic consumption on antibiotic resistance. Thereby, we derive a family of diversity measures whose members exhibit different degrees of complexity. Most important, we extent these measures such that they account for the assessment of temporal changes in heterogeneity including otherwise undetected diversity-invariant permutations of antibiotics consumption and prevalence of resistant pathogens. We apply a correlation analysis for the assessment of associations between changes of heterogeneities on the antibiotics and on the pathogen side. As a showcase, which serves as a proof-of-principle, we apply the derived methods to records of antibiotic consumption and prevalence of antibiotic-resistant germs from University Hospital Dresden. Besides the quantification of heterogeneities of antibiotics consumption and antibiotic resistance, we show that a reduction of prevalence of antibiotic-resistant germs correlates with a temporal change of similarity with respect to the first observation of antibiotics consumption, although heterogeneity remains approximately constant. Although an interventional study is pending, our mathematical framework turns out to be a viable concept for the assessment and optimisation of control strategies intended to reduce antibiotic resistance.

Preprint SHORT NOTE | doi:10.20944/preprints202007.0526.v1

Confirmed and Unreported COVID-19 Death Counts: An Assessment of Reporting Discrepancy

Mazbahul G Ahamad, Fahian Tanin

Subject: Medicine And Pharmacology, Epidemiology And Infectious Diseases Keywords: COVID-19; Unreported COVID-19 Death; Provisional COVID-19 Death; Death Reporting Discrepancy; Bangladesh

Online: 22 July 2020 (11:32:05 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202003.0330.v1

Thermal and Energy-Efficiency Assessment of Novel Hybrid CLT-Glass Facade Elements

Vlatka Rajčić, Nikola Perković, Chiara Bedon, Jure Barbalić, Roko Zarnic

Subject: Engineering, Civil Engineering Keywords: Cross-Laminated Timber (CLT); laminated glass; hybrid facade element; thermal performance; energy efficiency; numerical modelling

Online: 23 March 2020 (03:41:03 CET)

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Preprint ARTICLE | doi:10.20944/preprints201907.0339.v2

Groundwater Quality Assessment for Drinking and Agricultural Purposes in Tabriz Aquifer, Iran

Esmaeil Asadi, Mohammad Isazadeh, Saeed Samadianfard, Mohammad Firuz Ramli, Amir Mosavi, Shahab Shamshirband, Kwok-Wing Chau

Subject: Engineering, Civil Engineering Keywords: Water Quality Index; irrigation water quality; Tabriz Aquifer

Online: 9 September 2019 (08:42:20 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201906.0201.v1

Assessment of Standards and Codes Dedicated to CFRP Confinement of RC Columns

Stefan Kaeseberg, Dennis Messerer, Klaus Holschemacher

Subject: Engineering, Civil Engineering Keywords: reinforced concrete; columns; confinement; CFRP; load bearing capacity; standards

Online: 20 June 2019 (11:50:22 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201901.0303.v1

Performance Assessment Model for Municipal Solid Waste Management systems: Development and Implementation

Hatem Abdulaziz AlHumid, Husnain Haider, Saleem S. AlSaleem, Majed Alinizzi, Md. Shafiquzamman, Rehan Sadiq

Subject: Engineering, Civil Engineering Keywords: solid waste management; performance assessment; fuzzy rule-based modeling; performance indicators; Simulink MATLAB

Online: 30 January 2019 (06:55:00 CET)

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Preprint ARTICLE | doi:10.20944/preprints201812.0166.v1

Operational Risk of Insecurity using Control Self Risk Assessment and Linear Programming

Monday Osagie Adenomon, Ezekiel Awhigbo Bulus

Subject: Computer Science And Mathematics, Security Systems Keywords: Risk, Security, Linear programming, Nasarawa Eggon and CSRA

Online: 13 December 2018 (09:45:41 CET)

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Preprint ARTICLE | doi:10.20944/preprints201803.0259.v1

MOSH Syndrome (Male Obesity Secondary Hypogonadism): Clinical Assessment and Possible Therapeutic Approaches

Antonino De Lorenzo, Annalisa Noce, Eleonora Moriconi, Tiziana Rampello, Giulia Marrone, Nicola Di Daniele, Valentina Rovella

Subject: Medicine And Pharmacology, Dietetics And Nutrition Keywords: MOSH syndrome; lifestyle change; food addiction; aromatase activity; testosterone/estradiol ratio

Online: 30 March 2018 (06:19:03 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201803.0161.v1

A New Three-dimensional Assessment Model and Optimization for Acoustic Positioning System

Lin Zhao, Xiaobo Chen, Yong Hao, Chengcai Lv, Lianhua Yu

Subject: Engineering, Electrical And Electronic Engineering Keywords: acoustic positioning system; three-dimensional assessment model; positioning accuracy; DOP; optimal configuration

Online: 19 March 2018 (11:43:18 CET)

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Preprint ARTICLE | doi:10.20944/preprints201802.0117.v1

Assessment of the History and Cultural Inclusion of Public Art in Pakistan

Syed Asifullah Shah, Ashfaq Ahmad Shah, Xianfeng Li

Subject: Arts And Humanities, Art Keywords: Public Art; Cultural identity; Islamic society; Art history; Pakistan.

Online: 18 February 2018 (13:16:07 CET)

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Preprint REVIEW | doi:10.20944/preprints202302.0049.v1

Vitamin K and the Visual System: A Narrative Review

Michael A. Mong

Subject: Medicine And Pharmacology, Ophthalmology Keywords: vitamin K; vitamin K1; vitamin K2; eye; visual function; cognitive function; vitamin K-dependent protein; matrix Gla protein; ferroptosis

Online: 3 February 2023 (01:15:33 CET)

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Preprint REVIEW | doi:10.20944/preprints202306.0380.v1

A Novel Global Medicines Agency (GMA) Formation Proposal for Making Biotechnology Drugs Affordable: Starting with the League of Arab States.

F Sarfaraz K. Niazi

Subject: Public Health And Healthcare, Health Policy And Services Keywords: Biosimilars 1; Arab states 1; regulatory guideline 3; harmonization 4; centralized approval 5; EMA 6; FDA 7; Global Medicine Authority (GMA) 8.

Online: 6 June 2023 (08:49:00 CEST)

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