REVIEW
|
doi:10.20944/preprints202407.1445.v1
Subject:
Biology And Life Sciences,
Food Science And Technology
Keywords:
natural polysaccharides; gut microbiome; short-chain fatty acids; bile acids; branch-chain amino acids; tryptophan metabolism; metabolic diseases
Online: 18 July 2024 (09:04:08 CEST)
REVIEW
|
doi:10.20944/preprints202404.0172.v1
Subject:
Public Health And Healthcare,
Primary Health Care
Keywords:
cardiorespiratory fitness; estimated CRF; metabolic risk factors; noncommunicable diseases; public health; eCRF prediction models; hypertension; hyperglycemia; dyslipidemia; obesity
Online: 2 April 2024 (10:32:26 CEST)
REVIEW
|
doi:10.20944/preprints202311.1772.v1
Subject:
Biology And Life Sciences,
Anatomy And Physiology
Keywords:
prediabetes; senescence; blood-based biomarkers; aging; age-related diseases; inflammation; oxidative stress; vascular dynamics; metabolic disorders; chronic inflammation
Online: 29 November 2023 (04:48:13 CET)
ARTICLE
|
doi:10.20944/preprints202309.2144.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
mitochondrial respiratory chain complexes; supercomplexes; cAMP/PKA signaling pathway; soluble adenylate cyclase; metabolic flux theory; mitochondrial membrane potential
Online: 30 September 2023 (08:01:36 CEST)
ARTICLE
|
doi:10.20944/preprints202303.0446.v1
Subject:
Biology And Life Sciences,
Biology And Biotechnology
Keywords:
Control coefficients; Metabolic Control Analysis; Systems Biology; Genomics; Pharmacokinetic principles; systems biology and PBPK; time-dependent control analysis
Online: 27 March 2023 (05:04:24 CEST)
ARTICLE
|
doi:10.20944/preprints201910.0333.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
metabolic engineering; lycopene; MEP pathway; 1-deoxy-D-xylulose-5-phosphate synthase; farnesyl diphosphate synthase; Vibrio sp. dhg
Online: 29 October 2019 (10:40:18 CET)
REVIEW
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
metabolic functionalization of alkyl moieties in drug molecules; structure influence on metabolic functionalization of alkyl moieties; mechanism of alkyl free radical hydroxy functionalization; pharmacologic activity of hydroxy and carboxy functionalized alkyl moieties in drug molecules; primary and auxiliary pharmacophores; auxophores
Online: 11 March 2020 (03:20:58 CET)
ARTICLE
|
doi:10.20944/preprints202406.0762.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
high-throughput screening; metabolic stability; ambient mass spectrometry; LA-REIMS; biomimetic metalloporphyrin; lead profiling; in vitro models; drug metabolism
Online: 12 June 2024 (14:15:32 CEST)
REVIEW
|
doi:10.20944/preprints202404.1068.v1
Subject:
Medicine And Pharmacology,
Endocrinology And Metabolism
Keywords:
type 2 diabetes mellitus; prediabetes; pregnancy; Maternal HPA axis; fetal HPA axis; programming; fetal development; placenta; glucocorticoids; metabolic diseases
Online: 16 April 2024 (17:24:13 CEST)
REVIEW
|
doi:10.20944/preprints202402.1435.v1
Subject:
Medicine And Pharmacology,
Internal Medicine
Keywords:
secondary movement disorders; dystonia; chorea; athetosis; myoclonus; tics; tremor; drug-induced movement disorders; post-infectious movement disorders; metabolic disorders
Online: 26 February 2024 (11:45:00 CET)
REVIEW
|
doi:10.20944/preprints202310.0576.v1
Subject:
Medicine And Pharmacology,
Medicine And Pharmacology
Keywords:
methylglyoxal; glyoxalase; advanced glycation end products; MG-H1, metabolic syndrome; insulin resistance, diabetes mellitus; cardiovascular disease; metformin; methylglyoxal scavengers
Online: 10 October 2023 (12:31:23 CEST)
REVIEW
|
doi:10.20944/preprints202308.1424.v1
Subject:
Biology And Life Sciences,
Anatomy And Physiology
Keywords:
Blood-brain barriier; Blood-cerebrospinal fluid barrier; Endothelial glycocalyx; Enlarged perivascular spaces; Metabolic Syndrome; Neuroinflammation; Obesity; Perivascular spaces; T2DM
Online: 21 August 2023 (08:06:57 CEST)
ARTICLE
|
doi:10.20944/preprints202204.0248.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
granulosa cells; heat stress; integrated analysis; transcriptomics; metabolomics; differentially ex-pressed genes; metabolites; signaling pathways; metabolic pathways; cancer pathways
Online: 27 April 2022 (05:08:15 CEST)
REVIEW
|
doi:10.20944/preprints202106.0163.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
white biotechnology; metabolic engineering; non-conventional yeast; oleaginous yeast; cell factory; heterologous expression; biodiversity; Yarrowia lipolytica; Yarrowia clade; GMO
Online: 7 June 2021 (10:50:26 CEST)
ARTICLE
Subject:
Medicine And Pharmacology,
Endocrinology And Metabolism
Keywords:
Body mass index, Metabolic syndrome, Obesity, Obesity paradox, Telomere, Waist circumference, Waist-to-hip ratio, Waist-to-height ratio
Online: 4 September 2019 (14:20:32 CEST)
ARTICLE
|
doi:10.20944/preprints202406.0573.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Metabolic Syndrome (MetS); Machine Learning (ML); Feature Importance; Borda Count Method; Predictive Modeling; Ensemble Models; Cross-Validation; Non-Invasive Diagnostics
Online: 10 June 2024 (12:50:21 CEST)
REVIEW
|
doi:10.20944/preprints202309.2106.v1
Subject:
Biology And Life Sciences,
Neuroscience And Neurology
Keywords:
BBB; endothelial glycocalyx; enlarged perivascular spaces; metabolic syndrome; neuroinflammation; neurovascular unit; obesity; perivascular spaces; perivascular unit; type 2 diabetes mellitus
Online: 29 September 2023 (11:14:38 CEST)
ARTICLE
|
doi:10.20944/preprints202105.0415.v1
Subject:
Computer Science And Mathematics,
Algebra And Number Theory
Keywords:
metabolic pathways; graph comparison; graph alignment; graph depth-first traversal; graph breadth-first traversal; global alignment; local alignment; semiglobal alignment
Online: 18 May 2021 (10:45:18 CEST)
REVIEW
|
doi:10.20944/preprints202103.0571.v3
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
diet; calorie restriction; ketosis; fasting; health span; lifespan; metabolic syndrome; insulin resistance; chronic non-communicable diseases; low-calorie; low-carb
Online: 12 April 2021 (13:06:01 CEST)
ARTICLE
|
doi:10.20944/preprints202407.0097.v1
Subject:
Medicine And Pharmacology,
Pathology And Pathobiology
Keywords:
advanced glycation end products (AGEs); metabolic dysfunction; protein relation structure-function; spectroscopic analysis; conformational changes; catalytic aging; molecular wear; enzymatic rescue
Online: 2 July 2024 (02:28:47 CEST)
ARTICLE
|
doi:10.20944/preprints202206.0177.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Deuterium-depleted water (DDW); deuterium-depleted organic compounds (DDOC); anticancer drug development; D/H ratio; production of metabolic water; ketogenic diet
Online: 13 June 2022 (09:49:32 CEST)
ARTICLE
|
doi:10.20944/preprints202402.0098.v1
Subject:
Biology And Life Sciences,
Biology And Biotechnology
Keywords:
Anthocyanidins; anthocyanidin-3,5-O-diglucoside; anthocyanidin-3,5-O-monoglucoside; anthocyanins; HPLC-quadrupole time-of-flight tandem mass spectrometer; Vitis rotundifolia; metabolic profiling
Online: 2 February 2024 (09:18:46 CET)
ARTICLE
|
doi:10.20944/preprints202401.1980.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Human disease model; Inherited Metabolic Disorders; Inborn Error of Metabolism; Nonketotic Hyperglycinemia; GLDC; iPSC; iPSC-derived astrocytes; serine-glycine-one-carbon metabolism
Online: 29 January 2024 (04:40:23 CET)
REVIEW
|
doi:10.20944/preprints202401.1912.v1
Subject:
Biology And Life Sciences,
Life Sciences
Keywords:
Enzyme functions; domains of unknown functions; central metabolic pathways; biosynthesis; biosynthetic gene clusters; cryptic pathways; orphan pathways; silent pathways; metabolite repair enzymes
Online: 26 January 2024 (11:07:28 CET)
ARTICLE
|
doi:10.20944/preprints202111.0229.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Total metabolic tumor volume; bone marrow to liver ratio; PET/CT; overall survival; immunotherapy; immune checkpoint inhibitor; standardized uptake value; response prediction
Online: 12 November 2021 (14:59:35 CET)
ARTICLE
|
doi:10.20944/preprints202404.0935.v2
Subject:
Biology And Life Sciences,
Biology And Biotechnology
Keywords:
metabolic boundary; autopoiesis without spatial boundaries; characterization of living systems; self-production; autocatalysis; computational autopoiesis; metabolism; complex systems; emergence of individuality; network science
Online: 24 May 2024 (12:55:41 CEST)
REVIEW
|
doi:10.20944/preprints202401.2227.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
Cytolytic Activity (CYT); Tumor-Infiltrating Lymphocytes (TILs); Gene Expression Profiling; Spatial Analysis Techniques; Immune Checkpoint Pathways; Tumor Microenvironment (TME); Antigen Presentation; Metabolic Pathways
Online: 31 January 2024 (12:32:26 CET)
REVIEW
|
doi:10.20944/preprints202311.0804.v1
Subject:
Medicine And Pharmacology,
Endocrinology And Metabolism
Keywords:
metabolic dysfunction-associated fatty liver disease (MAFLD); chronic viral hepatitis; Hepatitis B virus (HBV); Hepatitis C virus; Hepatic Fibrosis; Cirrhosis; and Hepatocellular carcinoma
Online: 14 November 2023 (05:28:01 CET)
REVIEW
|
doi:10.20944/preprints201907.0265.v2
Subject:
Medicine And Pharmacology,
Neuroscience And Neurology
Keywords:
Aging; Alzheimer’s disease; brain insulin resistance; db/db diabetic mouse model; diabetic cognopathy; insulin resistance; metabolic syndrome; mixed dementia; obesity; type 2 diabetes mellitus
Online: 9 September 2019 (06:12:15 CEST)
ARTICLE
|
doi:10.20944/preprints201809.0201.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Suprachiasmatic nucleus (SCN); Circadian clock; Soleus Muscle (SM); Brown adipose tissue (BAT); liver; 6-meal feeding; Respiratory exchange ratio (RER); Clock genes; metabolic genes; Shift work.
Online: 11 September 2018 (14:21:48 CEST)
ARTICLE
|
doi:10.20944/preprints202104.0788.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
SARS-CoV-2; COVID-19; Flux Balance Analysis (FBA); Genome-Scale Metabolic Models; Target Identification; Reaction Knock-Out; Structural Proteins; Purine Metabolism; Pyrimidine Metabolism; B.1.1.7; B.1.351
Online: 30 April 2021 (15:14:06 CEST)
ARTICLE
|
doi:10.20944/preprints202309.1729.v1
Subject:
Medicine And Pharmacology,
Gastroenterology And Hepatology
Keywords:
quantiative ultrasound; attenuation coefficient; backscatter-distribution coefficient; liver stiffness; non-alcoholic fatty liver disease; metabolic-associated fatty liver disease; hepatic steatosis; ultrasound-estimated fat fraction; proton density fat fraction
Online: 26 September 2023 (05:36:41 CEST)
ARTICLE
|
doi:10.20944/preprints202001.0139.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
bacteria; barium monocarboxylates; chemical deposition techniques; free fatty acids (FFAs); Langmuir film technology; matrix-assisted laser desorption/ionization-time of flight mass spectrometry (MALDI-TOF-MS); metabolic fingerprinting; rhizobia
Online: 13 January 2020 (13:25:49 CET)
REVIEW
|
doi:10.20944/preprints202206.0040.v1
Subject:
Chemistry And Materials Science,
Analytical Chemistry
Keywords:
Microsampling; sample miniaturisation; dried blood spot (DBS); dried plasma spot (DPS); dried serum spot (DSS); metabolic phenotyping; gas chromatography-mass spectrometry (GC-MS); liquid chromatog-raphy-mass spectrometry (LC-MS)
Online: 3 June 2022 (09:53:13 CEST)
REVIEW
|
doi:10.20944/preprints202202.0027.v1
Subject:
Medicine And Pharmacology,
Neuroscience And Neurology
Keywords:
neurodegenerative diseases - multiple sclerosis; new therapeutic options for multiple sclerosis and other 24 neurodegenerative diseases. pH in cancer and neurodegenerative diseases - cancer and neurodegeneration as opposed processes - 25 metabolic e
Online: 2 February 2022 (09:42:40 CET)
ARTICLE
|
doi:10.20944/preprints202203.0290.v3
Subject:
Biology And Life Sciences,
Biology And Biotechnology
Keywords:
host-virus interactions; tissue-specific model; COVID-19; SARS-CoV-2; antiviral targets; flux balance analysis; flux variability analysis; reaction knockout; host-derived enforcement; metabolic modeling; virus mutations; software engineering; Python
Online: 17 January 2023 (01:50:23 CET)
REVIEW
|
doi:10.20944/preprints202408.0733.v1
Subject:
Medicine And Pharmacology,
Reproductive Medicine
Keywords:
endometrium; basalis and functionalis; estradiol; progesterone; production; metabolic clearance rate; transport; growth factors; endometrial thickness; factors influencing endometrial thickness; markers of decidualization; histological dating; pinopodes; treatment for endometrial assessment useful to embryo implanytation
Online: 12 August 2024 (08:07:17 CEST)
ARTICLE
|
doi:10.20944/preprints201909.0247.v3
Subject:
Biology And Life Sciences,
Anatomy And Physiology
Keywords:
obesity; obesity paradox; diabetes; insulin resistance (IR); whole body insulin resistance (WBIR); tissue specific insulin resistance; muscle insulin resistance (MIR); subcutaneous insulin resistance (s AIR); visceral adipose insulin resistance (v AIR); hepatic insulin resistance (HIR); lipid induced insulin resistance (LIIIR); glycation induced insulin resistance (GIIIR); metabolic syndrome
Online: 14 February 2023 (09:38:06 CET)