ARTICLE
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doi:10.20944/preprints202401.1381.v1
Subject:
Biology And Life Sciences,
Animal Science, Veterinary Science And Zoology
Keywords:
Wound dressing; Bacterial susceptibility; Minimum Inhibitory Concentration (MIC); Minimum Bactericidal Concentration (MBC); Manuka honey; hypertonic saline; Polyhexamethylene biguanide (PHMB); Silver SulfadiazineAbbreviationsPHMB - Polyhexamethylene biguanideMIC- Minimum inhibitory concentrationMBC- Minimum bactericidal concentrationSSC- Silver sulfadiazine creamCFU- Colony forming unitsATCC- American Type Culture Collectio
Online: 18 January 2024 (10:04:04 CET)
REVIEW
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doi:10.20944/preprints202209.0139.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
Bacillus Calmette-Guérin (BCG); tuberculosis; Non-tuberculous mycobacteria (NTM); nonspecific effects; Trained Immunity; Type 1 Diabetes; Multiple Sclerosis; Parkinson’s Disease; Alzheimer’s disease; Mycobacterium avium ss. paratuberculosis (MAP); molecular mimicry; Global Burden of Disease
Online: 12 September 2022 (09:36:16 CEST)
HYPOTHESIS
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doi:10.20944/preprints202005.0144.v1
Subject:
Medicine And Pharmacology,
Medicine And Pharmacology
Keywords:
COVID-19, SARS-CoV-2, pyridoxal 5'-phosphate, pyridoxine, vitamin B6, immune response, IL-6, TNF, type I interferon, lymphopenia, blood clotting, coagulopathy, cytokine storm, sphingosine-1-phosphate, kynurenine, inflammasome, serine hydroxymethyltransferase 2 (SHMT2), hypertension, angiotensin
Online: 8 May 2020 (12:36:03 CEST)
ARTICLE
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doi:10.20944/preprints201810.0088.v1
Subject:
Chemistry And Materials Science,
Biomaterials
Keywords:
There are many molecules used as drug carrier. TUD-1 is a newly synthesized mesoporous silica (SM) molecule possess two important features; consists of mesoporous so it is very suitable to be drug carrier in addition to that it has the ability to induce apoptosis in cancer cells. However, the effect of TUD-1 appears to act as cell death inducer, regardless of whether it is necrosis or apoptosis. Unfortunately, recent studies indicate that a proportion of cells undergo necrosis rather than apoptosis, which limits the use of TUD-1 as a secure treatment. On the other hand, lithium considered as necrosis inhibitor element. Hence, current study based on the idea of production a new Li/TUD-1 by incorporated mesoporous silica (TUD-1 type) with lithium in order to produce a new compound that has the ability to activate apoptosis by mesoporous silica (TUD-1 type) and at the same time can inhibit the activity of necrosis by lithium. Herein, lithium was incorporated in TUD-1 mesoporous silica by
Online: 4 October 2018 (15:54:02 CEST)