(1) Background: The literature has demonstrated several pathways which links obesity and stress. Thus, new approaches of weight management programs must also integrate health coach-ing and telemonitoring for overall health and wellbeing. The aim of the study is to measure stress, anxiety, and depression scales (DASS-21) in overweight and obese participants who joined a pilot randomized controlled trial (RCT) and the association between changes in DASS-21 scores and changes in anthropometric measures.; (2) Methods: 50 participants have been enrolled in a ran-domized controlled trial and divided in two groups; Intervention group who received a hy-pocaloric diet remotely, weekly telemonitoring and monthly health coaching; Control group who only followed a the hypocaloric diet without any support. The Arabic version of the Depression Anxiety Stress Scale (DASS-21) was used to measure depression, anxiety, and stress scales; (3) Results: Data revealed that participants from the intervention group had a significant decrease in anxiety scales after 3months when compared to the control group. In addition, correlation be-tween depression, anxiety, stress, and all anthropometric measures in the intervention group showed a moderate significant positive correlation between changes in waist circumference and depression. (4) Conclusions: Findings confirms that integrating health coaching and telemonitor-ing have a strong potential in improving wellbeing and weight loss.

(1) Background: General nutrition knowledge is a fundamental pillar of well-being and healthy lifestyles. The aim of this study was to investigate the effect of a weight loss intervention sup-ported with telemonitoring and telehealth coaching, on improving the general nutrition in over-weight and obese individuals. (2) Methods: A total of 30 participants have completed the trial at the 3-month visit, and a total of 25 have completed the trial at the 6-month visit. All participants have enrolled in a randomized controlled trial (RCT) and received a hypocaloric tailored diet and 3 online nutrition education sessions over a 6-month period. Participants were randomly di-vided into two groups, where the intervention group were supported with weekly telemonitoring and monthly telehealth coaching vs. a control group. The Arabic validated General Nutrition Knowledge Questionnaire (GNKQ) was used, which covered 4 sections; dietary recommenda-tions; food groups and nutrient sources; healthy food choices; associations between diet–disease and weight (3) Results: Findings showed that both intervention and control groups have im-provements in GNKQ scores over time, with the intervention group demonstrating significant in-creases in overall nutrition knowledge and specific areas such as the diet-disease relationship and weight management at 3 months. In addition, changes in GNKQ scores had a significant negative association with BMI and visceral fat percentage. The findings underline the benefits of supporting nutrition interventions with telemonitoring and telehealth coaching suggesting that increased nutrition knowledge may relate to lower body fat metrics. Still, small sample size and high attrition rate of participants were considered a significant limitation in the current study, where large populations is required to confirm reliability of the obtained findings.