The type of review presented to the reader contains a reflection on the aberrations related to the wound healing process that often result in real pathologies or malformations. The reader is therefore invited through literature updates to reflect on the complex problem of wound healing and then gain knowledge on the problem of chronic wounds, keloids and hypertrophic scars. These problems are relevant in everyday life but still today they are not resolved and there is no knowledge of the cellular mechanisms present. Once again, as has been widely debated in recent years, knowledge of the cellular and molecular mechanisms underlying these pathologies is fundamental for the treatment of these.