Review
Version 1
Preserved in Portico This version is not peer-reviewed
HIV and Human Coronavirus Coinfections: A Historical Perspective
Version 1
: Received: 31 July 2020 / Approved: 2 August 2020 / Online: 2 August 2020 (13:02:10 CEST)
Version 2 : Received: 3 August 2020 / Approved: 4 August 2020 / Online: 4 August 2020 (07:36:38 CEST)
Version 2 : Received: 3 August 2020 / Approved: 4 August 2020 / Online: 4 August 2020 (07:36:38 CEST)
A peer-reviewed article of this Preprint also exists.
Makoti, P.; Fielding, B.C. HIV and Human Coronavirus Coinfections: A Historical Perspective. Viruses 2020, 12, 937. https://doi.org/10.3390/v12090937 Makoti, P.; Fielding, B.C. HIV and Human Coronavirus Coinfections: A Historical Perspective. Viruses 2020, 12, 937. https://doi.org/10.3390/v12090937
Abstract
Seven human coronaviruses are known to infect humans. The most recent one, SARS-CoV-2, was isolated and identified in January 2020 from a patient presenting with severe respiratory illness in Wuhan, China. Even though viral coinfections have the potential to influence the resultant disease pattern in the host, very few studies have looked at the disease outcomes in patients infected with both HIV and hCoVs. Groups are now reporting that even though HIV-positive patients can be infected with hCoVs, the likelihood of developing severe CoV-related diseases in these patients is often similar to what is seen in the general population. This review aimed to summarize the current knowledge of coinfections reported for the HIV and hCoVs. Also, based on the available data, this review aimed to theorize why HIV-positive patients do not frequently develop severe CoV-related diseases.
Keywords
COVID-19; immunosuppression; malnutrition; cytokine storm; SARS-CoV-2; coronavirus
Subject
Biology and Life Sciences, Virology
Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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