Review
Version 2
Preserved in Portico This version is not peer-reviewed
Gut Microbiota and Nonalcoholic Fatty Liver Disease: Insights on Mechanism and Therapy
Version 1
: Received: 10 September 2017 / Approved: 11 September 2017 / Online: 11 September 2017 (08:22:24 CEST)
Version 2 : Received: 6 October 2017 / Approved: 6 October 2017 / Online: 6 October 2017 (16:15:42 CEST)
Version 2 : Received: 6 October 2017 / Approved: 6 October 2017 / Online: 6 October 2017 (16:15:42 CEST)
A peer-reviewed article of this Preprint also exists.
Ma, J.; Zhou, Q.; Li, H. Gut Microbiota and Nonalcoholic Fatty Liver Disease: Insights on Mechanisms and Therapy. Nutrients 2017, 9, 1124, doi:10.3390/nu9101124. Ma, J.; Zhou, Q.; Li, H. Gut Microbiota and Nonalcoholic Fatty Liver Disease: Insights on Mechanisms and Therapy. Nutrients 2017, 9, 1124, doi:10.3390/nu9101124.
Abstract
Gut microbiota play critical roles in development of obese-related metabolic diseases such as nonalcoholic fatty liver disease (NAFLD), type 2 diabetes, and insulin resistance, which highlighted the potential of gut microbiota-targeted therapies on these diseases. There are various ways that can manipulate gut microbiota including probiotics, prebiotics, synbiotics, antibiotics and some active components from herbal medicines. In this review, we first reviewed the main roles of gut microbiota in mediating the development of NAFLD, and the advances in gut microbiota-targeted therapies on NAFLD in both the experimental and clinical studies, as well as the conclusions on the prospect of gut microbiota-targeted therapies in the future.
Keywords
Gut microbiota; obesity; insulin resistance, NAFLD; probiotic; prebiotic; symbiotic
Subject
Biology and Life Sciences, Endocrinology and Metabolism
Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Comments (0)
We encourage comments and feedback from a broad range of readers. See criteria for comments and our Diversity statement.
Leave a public commentSend a private comment to the author(s)
* All users must log in before leaving a comment