Aeromagnetic data coupled with Landsat ETM+ data and SRTM DEM have been processed in order to map regional hydrogeological structures in the basement complex region of Paiko, north-central Nigeria. Lineaments were extracted from derivative maps from aeromagnetic, Landsat ETM+ and SRTM DEM datasets. Ground geophysical investigation utilizing Radial Vertical Electrical Sounding (RVES) was established in nine transects comprising of four sounding stations which are oriented in three azimuths. Source Parameter Imaging (SPI) was employed to map the average depths structures from aeromagnetic dataset. Selected thematic layers which included lineaments density, lithologic, slope, drainage density and geomorphologic maps were integrated and modelled using ArcGIS to generate groundwater potential map of the area. Groundwater zones were classified into four categories: very good, good, moderate and poor according to their potential to yield sustainable water to drilled wells. Results from RVES survey reveal a close correlation to lineaments delineated from surface structural mapping and remotely sensed datasets. Hydrogeological significance of these orientations suggest that aeromagnetic data can be used to map relatively deep-seated fractures which are likely to be open groundwater conduits while remotely sensed lineaments and orientations delineated from the RVES survey may indicate areas of recharge. Regions with high lineament density have relatively better groundwater potential. This is attributable to areas having deep weathering profiles associated with intrusive bodies that have resulted in intense fracturing in the area. Drill depths in this area should target a minimum of 80 m to ensure sufficient and sustainable supplies to drilled wells. The outcome of this study should act as information framework that would guide the siting of productive water wells and while providing needed information for relevant agencies in need of data for the development of groundwater resources.