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Is H34 of ACE2 an indicator of the susceptibility to SARS-CoV-2? Clues from multi-species sequence analyses
Version 1
: Received: 5 June 2020 / Approved: 7 June 2020 / Online: 7 June 2020 (08:18:54 CEST)
How to cite: Lin, J.; Lyu, F.; Xiao, W.; Xu, Y.; Liu, Z. Is H34 of ACE2 an indicator of the susceptibility to SARS-CoV-2? Clues from multi-species sequence analyses. Preprints 2020, 2020060067 Lin, J.; Lyu, F.; Xiao, W.; Xu, Y.; Liu, Z. Is H34 of ACE2 an indicator of the susceptibility to SARS-CoV-2? Clues from multi-species sequence analyses. Preprints 2020, 2020060067
Abstract
SARS-CoV-2, the causal agent of the globally spreading COVID-19, is capable of infecting variable animals besides human being. We evaluated the potential susceptibility of important livestock, pets and aquatic mammals by performing a multi-species sequence analysis of ACE2 based on the reported affected and unaffected animals. We identified a triple amino acid pattern of ACE2, at position 30, 31 and 34, that might be associated with SARS-CoV-2 infection and H34 might be an indicator of the susceptibility to COVID-19.
Keywords
SARS-CoV-2; COVID-19; Angiotensin-converting enzyme 2; susceptibility; livestock; aquatic mammals
Subject
Biology and Life Sciences, Biochemistry and Molecular Biology
Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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