Review
Version 1
Preserved in Portico This version is not peer-reviewed
Lessons for SARS-CoV-2 Study (COVID-19 Disease) From Its Exosome Relatives
Version 1
: Received: 11 June 2020 / Approved: 12 June 2020 / Online: 12 June 2020 (09:01:02 CEST)
How to cite: Arsene, P. Lessons for SARS-CoV-2 Study (COVID-19 Disease) From Its Exosome Relatives. Preprints 2020, 2020060145. https://doi.org/10.20944/preprints202006.0145.v1 Arsene, P. Lessons for SARS-CoV-2 Study (COVID-19 Disease) From Its Exosome Relatives. Preprints 2020, 2020060145. https://doi.org/10.20944/preprints202006.0145.v1
Abstract
Our first modern global pandemic is caused by a nanosized lipid vesicle, called SARS-CoV-2. Its molecular structure and biogenesis have remarkable similarities with Extracellular Vesicles (EVs, most notably exosomes) that are constantly shed by all cells during their life. Their resemblance may not be a coincidence. Growing body of evidence has shown that EVs have significant roles in various biological processes, including viral infection, transmission and anti-viral response. Drawing comparison with the virus might shed light on how we could fight the COVID-19 disease. This may include novel EV research and diagnostics technologies as well as novel EV-based treatments.
Keywords
SARS-CoV-2; COVID-19; Exosome; Extracellular Vesicle; Diagnostics; Vaccine; Treatment
Subject
Biology and Life Sciences, Virology
Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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