Version 1
: Received: 16 June 2020 / Approved: 17 June 2020 / Online: 17 June 2020 (13:18:37 CEST)
How to cite:
Shahzad, K.; Abbas, F.; PANDEY, D.; Ajmal, S.; Khadim, M.; Tahir, M. U. Synthesis, Characterization and Biological Evaluation of Novel Tetrasubsituted Imidazole Compounds. Preprints2020, 2020060219. https://doi.org/10.20944/preprints202006.0219.v1
Shahzad, K.; Abbas, F.; PANDEY, D.; Ajmal, S.; Khadim, M.; Tahir, M. U. Synthesis, Characterization and Biological Evaluation of Novel Tetrasubsituted Imidazole Compounds. Preprints 2020, 2020060219. https://doi.org/10.20944/preprints202006.0219.v1
Shahzad, K.; Abbas, F.; PANDEY, D.; Ajmal, S.; Khadim, M.; Tahir, M. U. Synthesis, Characterization and Biological Evaluation of Novel Tetrasubsituted Imidazole Compounds. Preprints2020, 2020060219. https://doi.org/10.20944/preprints202006.0219.v1
APA Style
Shahzad, K., Abbas, F., PANDEY, D., Ajmal, S., Khadim, M., & Tahir, M. U. (2020). Synthesis, Characterization and Biological Evaluation of Novel Tetrasubsituted Imidazole Compounds. Preprints. https://doi.org/10.20944/preprints202006.0219.v1
Chicago/Turabian Style
Shahzad, K., Mudassar Khadim and Muhammad Usman Tahir. 2020 "Synthesis, Characterization and Biological Evaluation of Novel Tetrasubsituted Imidazole Compounds" Preprints. https://doi.org/10.20944/preprints202006.0219.v1
Abstract
A new class of tetrasubstituted imidazole based compounds was synthesized using a multicomponent one-pot synthesis scheme through a cyclo condensation reaction of benzil, aromatic primary amines, aldehydes and ammonium acetate in glacial acetic acid. The synthesized compounds have been analyzed and characterized by melting point, color, conductivity method, CHN analysis, FT-IR, and UV-Visible. The reaction proceeding was examined by TLC after regular intervals of period. To test biological activity, the synthesized compounds have been examined against various bacterial strains. From the analysis of the antibacterial activity of these synthesized compounds demonstrated that all three imidazole compounds have considerable to significant activity against the strains, and compound K2 was found potent comparatively.
Biology and Life Sciences, Biology and Biotechnology
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.