Preprint Communication Version 1 Preserved in Portico This version is not peer-reviewed

The Mirror Strategy of Nanoparticles against the Coronavirus

Version 1 : Received: 18 July 2020 / Approved: 19 July 2020 / Online: 19 July 2020 (20:56:28 CEST)

How to cite: Fakhroueian, Z.; Esmaeilzadeh, P.; Esmaeilzadeh, P. The Mirror Strategy of Nanoparticles against the Coronavirus. Preprints 2020, 2020070443. https://doi.org/10.20944/preprints202007.0443.v1 Fakhroueian, Z.; Esmaeilzadeh, P.; Esmaeilzadeh, P. The Mirror Strategy of Nanoparticles against the Coronavirus. Preprints 2020, 2020070443. https://doi.org/10.20944/preprints202007.0443.v1

Abstract

Research on the chemical mechanism and reciprocal behavior of the coronavirus relate to living organisms, engaging in the give and take of electrochemical mediators, is a very important, controversial and vital issue. What we should accept is the chemical identity of this scenario, and not preferably a characteristic of a biological system. This chemical reaction should be familiar, referring to the theory of chemical pathways involved in DNA/proteins in the body against aggressive guests (such as viruses). From the point of view of a chemist, this simple reaction is nothing more than an oxidation-reduction reaction (redox-stress signaling) which conducted and carried out by coronavirus in a biointerface medium. Thereby, oxidizing as well as reducing reagents should be very constructive, promoting development in such chemical process. We understand redox reactions as switchable thiol/disulfide exchanges (formation and cleavage of inherent disulfide bonds), then, we can hugely profit from redox-responsive nano-surfaces equipped with multiple new ionic and covalent interactions. This game-changing idea can substantiate by surface modified-nanoparticles to play powerful roles in synthesis of nano oxidizers as well as reducing agents in nanomedicine. Chemists and pharmacists must then explore new thoughts and present modern experiences/approaches of preparation nanoparticles and nanocomposites to create novel vaccines as well as coronavirus drugs. In this regard, this experience can also be so helpful for HIV/AIDS, which is caused by viruses.

Keywords

Coronavirus disease 2019; COVID-19 pandemic; HIV/AIDS; Nanoantivirals; Smart nanomaterials; Synergistic oxidant @ reductant agents, antiviral coatings; Oxidizer and Reductant Nano agents; Nanomedicine

Subject

Chemistry and Materials Science, Nanotechnology

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