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Hypothesis

Autoimmune Thrombotic Thrombocytopathy Associated with COVID-19 Infection or Vaccination: Learning from Heparin-induced Thrombocytopenia

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Michel Goldman^*

This version is not peer-reviewed

This preprints belongs to the Collection

Preprints on COVID-19 and SARS-CoV-2

Submitted:

08 April 2021

Posted:

09 April 2021

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Abstract

Prothrombotic thrombocytopathy mimicking heparin-induced thrombocytopenia has been observed in patients with severe COVID-19 and after immunisation with the Vaxzevria vaccine. Herein, we discuss the possible pathogenesis of this disorder focusing on the possible involvement of anti-platelet factor 4 (PFA) autoantibodies.

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Subject: Medicine and Pharmacology - Immunology and Allergy

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