Preprint
Technical Note

CiLiQuant: Quantification of RNA Junction Reads Based on Their Circular or Linear Transcript Origin

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Submitted:

09 September 2021

Posted:

10 September 2021

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Abstract
Distinguishing circular RNA (circRNA) reads from reads derived from the linear host transcript is a challenging task because of sequence overlap. We developed a computational approach, CiLiQuant, that determines the relative circular and linear abundance of transcripts and gene loci using backsplice and forward splice junction reads generated by existing mapping and circRNA discovery tools.
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Subject: Biology and Life Sciences  -   Biochemistry and Molecular Biology
Copyright: This open access article is published under a Creative Commons CC BY 4.0 license, which permit the free download, distribution, and reuse, provided that the author and preprint are cited in any reuse.
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