Decentralized Finance (DeFi) is an emerging and revolutionizing field with notable uncertainties of reliability to be used on a mass scale. On the other hand, Artificial Intelligence (AI) has proved to be a crucial helping tool in numerous domains. In this study, we present a systematic review of the utility of AI in Defi in terms of impact, reliability, and security and conduct exhaustive analysis. We further conclude from our extensive literature review that we can identify possible new research opportunities in AI to bridge the gap of trust between peers and make the integration of DeFi more agile in the near future.