The study investigated the comparative effect organic fertilizers on the growth of Khaya senegalensis (Desr). Four treatments were used for this research: T1 20g of poultry manure, T2 (20g of cow dung), T3 (10g of poultry Manure + 10g of cow dung), T4 (Control experiment). Growth parameters such as diameter, plant height and number of leaves were measured weekly over a period of twelve (12) weeks. Data obtained were subjected to ANOVA and mean separated using Duncan Multiple Range Test. on the height parameter assessed on Khaya Senegalensis, the highest plant height mean of 8.40cm was recorded in treatment 1(20g of poultry Manure) while the lowest mean plant height 7.19cm was recorded in treatment 4 (Control experiment). Also, the highest mean stem diameter was recorded in Treatment 1 with a value of 0.309mm from while the least was recorded in Treatment 4 with mean value of 2.1175mm. However, highest mean number of leaves was recorded treatment 1 (20g of poultry manure) while the least was observed in T3 (10g of poultry Manure + 10g of cow dung). The results showed that organic manure has considerable effect on the growth of Khaya senegalensis seedlings and it use should be encouraged. T3 (10g of poultry Manure + 10g of cow dung) is hereby recommended to be the best of all in the growth of Khaya senegalensis.