Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Numerical Simulation of a Model Describing Plaque Rupture Phenomena in Elastic Arteries with Bifurcated Stenosis

Version 1 : Received: 4 March 2023 / Approved: 7 March 2023 / Online: 7 March 2023 (07:32:27 CET)

How to cite: RAZZAQ, M. Numerical Simulation of a Model Describing Plaque Rupture Phenomena in Elastic Arteries with Bifurcated Stenosis. Preprints 2023, 2023030127. https://doi.org/10.20944/preprints202303.0127.v1 RAZZAQ, M. Numerical Simulation of a Model Describing Plaque Rupture Phenomena in Elastic Arteries with Bifurcated Stenosis. Preprints 2023, 2023030127. https://doi.org/10.20944/preprints202303.0127.v1

Abstract

The buildup of plaque in the arteries characterizes atherosclerosis, which causes the walls of the arteries to thicken, the lumen to narrow, and the wall to thin in certain areas. These changes can lead to alterations in blood flow, potentially resulting in aneurysms and heart attacks if left untreated. This paper presents a phenomenological model to explain the mechanics of plaque rupture in stenosed bifurcated elastic arteries. The model considers the interaction between the plaque and artery wall, blood flow, mechanical properties of the artery wall and plaque, and hemodynamic forces in the system. Using the Navier-Stokes equations to describe blood flow and elastic properties of artery walls, our study shows that blood flow can become turbulent, leading to backflow, vortices, and possible stagnation. Certain regions can become highly vulnerable and result in elevated heat transfer between blood and arterial walls, which can lead to the rupture of the plaque cap. The study focuses on blood flow features such as velocity profiles and wall displacement on fluid-structure interaction, which are consistent with the literature. Finally, we calculate the wall shear stress (WSS) for minimum and maximum times while considering elastic walls. Our findings may provide valuable insights into the mechanisms of plaque rupture and inform the development of improved diagnostic and therapeutic approaches.

Keywords

inite element method; Stenosis; Bifurcation; Wall shear stress; Elastic walls

Subject

Computer Science and Mathematics, Applied Mathematics

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