Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Anti-Cancer Activity of Phytochemical Extracts from Chromolaena odorata on Liver, Breast and Colorectal Cancer Cells: A Review

Version 1 : Received: 30 March 2023 / Approved: 4 April 2023 / Online: 4 April 2023 (04:37:21 CEST)

How to cite: Adu, O. M.; Yahaya, D. I.; Olanrewaju, D. O.; Ujah, F. E.; Onah, E. I. Anti-Cancer Activity of Phytochemical Extracts from Chromolaena odorata on Liver, Breast and Colorectal Cancer Cells: A Review. Preprints 2023, 2023040036. https://doi.org/10.20944/preprints202304.0036.v1 Adu, O. M.; Yahaya, D. I.; Olanrewaju, D. O.; Ujah, F. E.; Onah, E. I. Anti-Cancer Activity of Phytochemical Extracts from Chromolaena odorata on Liver, Breast and Colorectal Cancer Cells: A Review. Preprints 2023, 2023040036. https://doi.org/10.20944/preprints202304.0036.v1

Abstract

Siam weed, scientifically known as Chromolaena odorata and belonging to the Asteraceae family, is a fast-growing plant with prolific seed production. Although it is a traditional medicinal plant, it has become an agricultural weed in Africa and Asia, posing a threat to biodiversity and causing environmental damage. Despite this, C. odorata is highly regarded as a medicinal herb in tropical Africa, with anticancer effects on breast, liver, and colorectal cancer. However, it is important to regulate the intake of the plant extract as it can have a hepatotoxic effect on liver cells at higher doses. Further research needs to be conducted on the plant extract, and proper orientation and knowledge of its oral daily administration are necessary. This review summarizes current scientific investigations using ethanolic and methanolic aqueous extracts of C. odorata leaves on various cancer cells, to uncover its potential as an anticancer agent. The investigations were sourced from online databases like Google Scholar, PubMed, and other online-based journals.

Keywords

Chromolaena odorata; liver; breast; cancer; plant

Subject

Biology and Life Sciences, Biochemistry and Molecular Biology

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