Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Effect of Meloxicam in a Protocol of Balanced Anaesthesia with Propofol and Sevoflurane on the α- δ- γ-Tocopherols in Response to Inflammatory Oxidative Stress Induced by Ovariectomy in Dogs

Version 1 : Received: 30 April 2023 / Approved: 30 April 2023 / Online: 30 April 2023 (09:15:58 CEST)

How to cite: Costa, G. L.; Di Pietro, S.; Nava, V.; Licata, P.; Iannelli, N. M.; Leonardi, F.; Macrì, F.; Iannelli, D.; De Paoli, F.; Macrì, D.; Ferrantelli, V.; Angileri, V.; Bruschetta, G.; Interlandi, C. Effect of Meloxicam in a Protocol of Balanced Anaesthesia with Propofol and Sevoflurane on the α- δ- γ-Tocopherols in Response to Inflammatory Oxidative Stress Induced by Ovariectomy in Dogs. Preprints 2023, 2023041270. https://doi.org/10.20944/preprints202304.1270.v1 Costa, G. L.; Di Pietro, S.; Nava, V.; Licata, P.; Iannelli, N. M.; Leonardi, F.; Macrì, F.; Iannelli, D.; De Paoli, F.; Macrì, D.; Ferrantelli, V.; Angileri, V.; Bruschetta, G.; Interlandi, C. Effect of Meloxicam in a Protocol of Balanced Anaesthesia with Propofol and Sevoflurane on the α- δ- γ-Tocopherols in Response to Inflammatory Oxidative Stress Induced by Ovariectomy in Dogs. Preprints 2023, 2023041270. https://doi.org/10.20944/preprints202304.1270.v1

Abstract

The present clinical study was approved by the Review Board for Animals Care of the University of Parma prot N. 03/CESA /2023, which provided a consent to the clinical study: regulation (EU) no. 536/2014. (22A01712) (GU General Series n.65 of 18-03-2022); European Law (O.J. of E.C. L 358/1 12/18/1986), and USA Laws (Animal Welfare Assurance No A5594-01, Department of Health and Human Services, USA). The owners signed a voluntary informed consent form prior to the dogs’ enrollment in the study. Twenty female dogs, aged 1±1.5 months, and weighing 16± 0.5 kg were enrolled in the study. The inclusion criterion of the patients was to undergo ovariectomy surgery; dogs enrolled in this study had normal physiological, haematological and biochemical parameters.

Keywords

Analgesia; Dog; Meloxicam; Oxidative stress; Ovariectomy; Surgery; Tocopherols

Subject

Medicine and Pharmacology, Veterinary Medicine

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