PreprintReviewVersion 1Preserved in Portico This version is not peer-reviewed
Is modern medicine in need of an overhydration marker in kidney failure? The accuracy of available fluid overload markers and the potential of the new ones.
Version 1
: Received: 24 July 2023 / Approved: 9 August 2023 / Online: 9 August 2023 (12:44:33 CEST)
Version 2
: Received: 13 September 2023 / Approved: 14 September 2023 / Online: 15 September 2023 (11:01:27 CEST)
Version 3
: Received: 4 October 2023 / Approved: 5 October 2023 / Online: 5 October 2023 (14:28:42 CEST)
How to cite:
Nikitiuk, B. E.; Rydzewska-Rosołowska, A.; Kakareko, K.; Głowińska, I.; Hryszko, T. Is modern medicine in need of an overhydration marker in kidney failure? The accuracy of available fluid overload markers and the potential of the new ones.. Preprints2023, 2023071818. https://doi.org/10.20944/preprints202307.1818.v1
Nikitiuk, B. E.; Rydzewska-Rosołowska, A.; Kakareko, K.; Głowińska, I.; Hryszko, T. Is modern medicine in need of an overhydration marker in kidney failure? The accuracy of available fluid overload markers and the potential of the new ones.. Preprints 2023, 2023071818. https://doi.org/10.20944/preprints202307.1818.v1
Nikitiuk, B. E.; Rydzewska-Rosołowska, A.; Kakareko, K.; Głowińska, I.; Hryszko, T. Is modern medicine in need of an overhydration marker in kidney failure? The accuracy of available fluid overload markers and the potential of the new ones.. Preprints2023, 2023071818. https://doi.org/10.20944/preprints202307.1818.v1
APA Style
Nikitiuk, B. E., Rydzewska-Rosołowska, A., Kakareko, K., Głowińska, I., & Hryszko, T. (2023). Is modern medicine in need of an overhydration marker in kidney failure? The accuracy of available fluid overload markers and the potential of the new ones.. Preprints. https://doi.org/10.20944/preprints202307.1818.v1
Chicago/Turabian Style
Nikitiuk, B. E., Irena Głowińska and Tomasz Hryszko. 2023 "Is modern medicine in need of an overhydration marker in kidney failure? The accuracy of available fluid overload markers and the potential of the new ones." Preprints. https://doi.org/10.20944/preprints202307.1818.v1
Abstract
Overhydration (OH) is a common medical problem found in patients with kidney or heart failure, but still a specific marker has not been found. Clinicians today use bioimpedance spectroscopy (BIS), ultrasound (US) markers of fluid overload or markers of heart and kidney function like NT-pro-BNP, GFR or creatinine levels. New serum markers such as Ca-125, Galectin-3 (Gal-3), Adrenomedullin (AMD) and Urocortin-2 (UCN-2), are being researched with promising results. The need to discover a more precise marker of overhydration is dire mainly because physical examination is extremely imprecise. Signs and symptoms of fluid overload like edema or gradual increase of body mass are not always present, especially in patients with chronic kidney disease. This review paper summarizes actual knowledge of a patient's hydration status estimation focusing especially on kidney diseases.
Keywords
Fluid status 1; overhydration 2; hydration status 3; renal failure 4; kidney failure 5; heart failure 6; Ca-125 7; NT-pro-BNP 8; VEXUS 9; BIS 10
Subject
Medicine and Pharmacology, Urology and Nephrology
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.