Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Endoscopic Ultrasound in Pancreatic Duct Anomalies

Version 1 : Received: 24 August 2023 / Approved: 28 August 2023 / Online: 29 August 2023 (09:00:13 CEST)

A peer-reviewed article of this Preprint also exists.

Chatterjee, A.; Rana, S.S. Endoscopic Ultrasound in Pancreatic Duct Anomalies. Diagnostics 2023, 13, 3129. Chatterjee, A.; Rana, S.S. Endoscopic Ultrasound in Pancreatic Duct Anomalies. Diagnostics 2023, 13, 3129.

Abstract

Embryological development of pancreas is a complex phenomenon and therefore, it can have multiple developmental aberrations. Fortunately, majority of these pancreatic ductal anomalies are asymptomatic with no clinical relevance and are incidentally detected during diagnostic cross sectional imaging or endoscopic retrograde cholangiopancreatography (ERCP) or autopsy. Occasionally, pancreatic duct anomalies can result in symptoms like abdominal pain or recurrent pancreatitis. Also, accurate pre-operative diagnosis of ductal anomalies can prevent inadvertent duct injury during surgery. Conventionally, ERCP had been used for accurate diagnosis of pancreatic duct anomalies. However, because of being invasive and associated with risk of pancreatitis, it has been replaced with magnetic resonance cholangiopancreatography (MRCP). MRCP has demonstrated high sensitivity and specificity for diagnosis of ductal anomalies which can be further improved with use of secretin enhanced MRCP. Endoscopic ultrasound (EUS) is a new diagnostic and interventional tool in the armamentarium of endoscopists and has demonstrated promising results in detection of pancreatic duct variations and anomalies. In this article, we will focus on the role of EUS in diagnosis of various pancreatic duct anomalies.

Keywords

Pancreas divisum; Endosonography; Annular pancreas; Magnetic resonance cholangiopancreatography

Subject

Medicine and Pharmacology, Gastroenterology and Hepatology

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