Review
Version 1
Preserved in Portico This version is not peer-reviewed
Biomarkers of Postpartum Depression: A Narrative Review
Version 1
: Received: 20 September 2023 / Approved: 21 September 2023 / Online: 22 September 2023 (05:13:21 CEST)
A peer-reviewed article of this Preprint also exists.
Modzelewski, S.; Oracz, A.; Iłendo, K.; Sokół, A.; Waszkiewicz, N. Biomarkers of Postpartum Depression: A Narrative Review. J. Clin. Med. 2023, 12, 6519. Modzelewski, S.; Oracz, A.; Iłendo, K.; Sokół, A.; Waszkiewicz, N. Biomarkers of Postpartum Depression: A Narrative Review. J. Clin. Med. 2023, 12, 6519.
Abstract
Postpartum depression (PPD) is a disorder that impairs the formation of the relationship between mother and child, and reduces the quality of life for affected women to a functionally significant degree. Studying markers associated with PPD can help in early detection, prevention, or monitoring treatment. The purpose of this paper is to review biomarkers linked to PPD and to present selected theories on the pathogenesis of the disease based on data from biomarker studies. The complex etiology of the disorder reduces the specificity and sensitivity of markers, but they remain a valuable source of information to help clinicians. The biggest challenge of the future will be to translate high-tech methods for detecting markers associated with postpartum depression into more readily available and less costly ones. Population-based studies are needed to test the utility of potential PPD markers.
Keywords
postpartum depression, marker, biomarkers, peripartum, postpartum, cytokines, HPA, oxidative stress, genetics, nutrients, pathogenesis
Subject
Medicine and Pharmacology, Psychiatry and Mental Health
Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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