Review
Version 1
Preserved in Portico This version is not peer-reviewed
The Mycobacterium tuberculosis: A Silent Killer
Version 1
: Received: 24 September 2023 / Approved: 28 September 2023 / Online: 28 September 2023 (02:45:57 CEST)
How to cite: Oliveira, H. V. D.; Ferreira, J.; Matta, A. C.; Oliveira, M. The Mycobacterium tuberculosis: A Silent Killer. Preprints 2023, 2023091841. https://doi.org/10.20944/preprints202309.1841.v1 Oliveira, H. V. D.; Ferreira, J.; Matta, A. C.; Oliveira, M. The Mycobacterium tuberculosis: A Silent Killer. Preprints 2023, 2023091841. https://doi.org/10.20944/preprints202309.1841.v1
Abstract
Mycobacterium tuberculosis is the agent of tuberculosis, one of the most important infectious diseases in the world. This microorganism stands out from other bacteria, not only for its extremely high infection capacity, but also for its cellular characteristics that include an extremely resistant and hydrophobic cellular parade the passage of antibiotics. An incredible ability to adapt to adverse conditions inside the host as well as its vast arsenal of virulence factors that allow its survival within the inhospitable environment within the macrophage can be highlighted. This review aims to discuss several aspects of MTB microbiology, genetics, and physiology. We will address in this review details of the metabolism of MTB that allows it to replicate in the active phase and remain viable during latency, as well as the characteristics of its cell wall that contribute to the blockade of the immune response and its resistance to antibiotics.
Keywords
tuberculosis; Mycobacterium; physiology; mycolic acids; cell wall
Subject
Biology and Life Sciences, Immunology and Microbiology
Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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