Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Comparative Analysis of Immune-response in Humans Infected by Alpha, Delta and Omicron Strains of SARS-CoV-2

Version 1 : Received: 3 October 2023 / Approved: 4 October 2023 / Online: 4 October 2023 (07:54:10 CEST)

A peer-reviewed article of this Preprint also exists.

Bose, M., & Munshi, C. (2024). Comparative analysis of immune responses in humans infected with Alpha, Delta, and Omicron strains of SARS-CoV-2. Global Translational Medicine, 3(1), 2228. https://doi.org/10.36922/gtm.2228 Bose, M., & Munshi, C. (2024). Comparative analysis of immune responses in humans infected with Alpha, Delta, and Omicron strains of SARS-CoV-2. Global Translational Medicine, 3(1), 2228. https://doi.org/10.36922/gtm.2228

Abstract

COVID-19 pandemic outbreak challenged the global public health in last couple of years. Throughout the pandemic period, numbers of mutant strains of SARS- CoV-2 created challenges for the infected patients with diverse pathophysiology and immune response. Variant of Concern (VOC) alpha (B.1.1.7), delta (B.1.617.2) and omicron (B.1.1.529) grew most notable for causing the epidemiological manifestations, which eventually caused elevated infectivity resulting in significant mortality. This review indicates the comparative analysis of the immune-pathophysiological mechanisms in respect to the aforementioned strains of SARS-CoV-2.

Keywords

SARS-CoV-2, Immune response, Pandemic

Subject

Biology and Life Sciences, Immunology and Microbiology

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