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The Hidden Injury: Delayed Diagnosis of C2 Fracture Post Athletic Trauma

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16 October 2023

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18 October 2023

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Abstract
Cervical injuries from athletic activities are rare; they can have severe consequences if not diagnosed and managed promptly. The choice of diagnostic imaging modality is pivotal in ensuring timely and accurate diagnosis. We detail the case of a 19-year-old female athlete who sustained a C2 Durel Type II Subclass C fracture during a short-track speed skating championship. Initial evaluation using X-ray imaging at the athletic center medical facility did not detect the injury, allowing her to continue competing. Persistent pain led to further evaluation at our institution, where MRI and CT scans confirmed the fracture. Approximately 45 days post-injury, the patient underwent a successful surgical intervention utilizing O-arm CBCT navigation for C1-C2 dorsal fusion. Post-surgery, she embarked on a comprehensive rehabilitation program and fully recovered within 12 weeks. This case underscores the limitations of relying solely on X-ray imaging for diagnosing cervical fractures post-trauma. Our findings advocate prioritizing CT scans as a primary diagnostic tool in such scenarios, emphasizing the need for a robust diagnostic approach to ensure athlete safety and well.
Keywords: 
Subject: Medicine and Pharmacology  -   Orthopedics and Sports Medicine
Figure 1. Sagittal neck MRI, revealing the C2 Durel Type II subclass C fracture, Red arrows indi-cate the fracture site. A 19-year-old female athlete endured an unfortunate incident while participating in the European championship for short-track speed skating. During this accident, she sustained a significant facial impact, which led to the onset of distressing symptoms. Upon immediate evaluation at the athletic center medical facility, the patient re-ported severe craniocervical pain, rating it at a distressing 8/10 on the visual analogue scale (VAS). Physical examination revealed that any movement involving neck flexion, extension, or rotation exacerbated her pain significantly, resulting in a VAS score 10/10. In response to the incident, an X-ray examination was promptly conducted, and it revealed no apparent injuries, leading the medical team to grant her clearance to resume the competition. Remarkably, on the day of the accident, the patient showcased remarkable resilience by continuing and successfully completing three additional rounds of rac-ing.Despite her initial resolve, the patient endured ongoing discomfort, rating her pain at 4/10 on the VAS scale. Surprisingly, she actively participated in three more competitions involving at least 20 short-track speed skating rounds during this period. This discomfort persisted for an extended 29-day duration after the incident, leading to an MRI being conducted at a different hospital than ours. The radiologist at the external facility reported an old C2 Durel Type II, Subclass C fracture (Figure 1). Ongoing pain led the radiologist to refer the case to our department. Upon the patient’s arrival at our institution 41 days after the injury, the clinical presentation, recent accident history, and the extent of the fracture, which involved approximately one-third of the odontoid diameter, raised suspicions of a fresh fracture related to the accident. Subsequently, we performed a CT scan and a functional cervical spine CT, both of which confirmed the instability of the C2 Durel Type II, Subclass C fracture. The functional CT examination revealed a 5 mm movement in the fracture line (Figure 2). On the 45th day after the initial injury, the patient underwent a successful surgical procedure, utilizing intraoperative O-arm CBCT and Stealth Station Navigation System (SS8) for C1-C2 dorsal fusion, where we placed bi-lateral screws in the lateral masses of both C1 and C2 and connected them with a rod (Figure 3). This surgical intervention led to the successful repositioning and stabilization of the C1 odontoid (Figure 4). Following the surgical procedure, the patient embarked on a comprehensive rehabilitation program starting six weeks post-surgery. By the 12-week mark post-surgery, she had made a remarkable recovery, regaining full functionality, and was actively participating in speed skating training without experiencing any complaints. Now, 9 months after the incident, she was granted the medical clearance to be called to represent her home country in the following international ice-skating competition due to her amazing speedy recovery. In a broader context, it is noteworthy that over 14 years, from February 2009 to February 2023. Among 347 cases of C2 odontoid fractures, only 5 fractures (1.14%) in our institute were attributed to professional sports activities. These sports-related fractures encompassed cases linked to skiing, short-track speed skating, cross-motorcycling, and go-karting. Notably, 3 of these fractures occurred during winter sports. Different treatment modalities were employed for these cases, with ventral odontoid screw fixation used in two instances, dorsal C1-C2 screw fixation in 1 case, and the HALO fixation device employed in the remaining 2 cases. In general, evaluating an acute cervical spine injury is challenging. Clinicians recommend obtaining three distinct views of the cervical spine. These views encompass the anteroposterior, cross-table lateral, and open-mouth odontoid cervical radiographs [1,2]. However, due to the inherent limitations of conventional plain radiography, the standard approach has evolved to encompass the more widespread utilization of flexion/extension radiographs, CT scans, and MRI examinations, particularly for detecting subtle cervical spine injuries [3]. CT scans have emerged as the modality for effectively visualizing the cervical spine. Consequently, when CT imaging is deemed necessary, there is often no prerequisite for additional plain radiographic imaging [4]. Recent empirical data has suggested that CT imaging should be prioritized to assess the cervical spine rapidly and efficiently, potentially rendering conventional plain radiographic imaging unnecessary [5]. Moreover, in specific clinical scenarios such as neurologic deficits, the need to assess ligamentous injuries, or the imperative to rule out underlying pathologies, MRI may also be considered an invaluable diagnostic tool [6,7]. In light of the absence of clear-cut guidelines regarding the optimal imaging modality for cervical fracture diagnosis, healthcare professionals must thoroughly understand the strengths and limitations of each option. In athletic events, continuous video recording can offer invaluable insights into the injury’s nature, assisting clinicians in making an informed choice regarding the most suitable imaging technique. The selection of an imaging method plays a pivotal role in determining the accuracy and speed of diagnosis, ultimately affecting patient outcomes. While CT and MRI remain the foundations of cervical fracture diagnosis, clinicians must adopt a holistic approach. This involves relying on imaging results and considering the clinical presentation, mechanism of injury, and any associated symptoms [8,9]. The synergy between the patient’s anamnesis, clinical picture, and imaging modalities ensures a comprehensive evaluation, minimizing the risk of misdiagnosis. As the field advances, ongoing research and collaboration between radiologists, neurosurgeons, and orthopedic specialists will be crucial in refining diagnostic protocols ensuring that patients receive timely and appropriate care.
Figure 1. Sagittal neck MRI, revealing the C2 Durel Type II subclass C fracture, Red arrows indi-cate the fracture site. A 19-year-old female athlete endured an unfortunate incident while participating in the European championship for short-track speed skating. During this accident, she sustained a significant facial impact, which led to the onset of distressing symptoms. Upon immediate evaluation at the athletic center medical facility, the patient re-ported severe craniocervical pain, rating it at a distressing 8/10 on the visual analogue scale (VAS). Physical examination revealed that any movement involving neck flexion, extension, or rotation exacerbated her pain significantly, resulting in a VAS score 10/10. In response to the incident, an X-ray examination was promptly conducted, and it revealed no apparent injuries, leading the medical team to grant her clearance to resume the competition. Remarkably, on the day of the accident, the patient showcased remarkable resilience by continuing and successfully completing three additional rounds of rac-ing.Despite her initial resolve, the patient endured ongoing discomfort, rating her pain at 4/10 on the VAS scale. Surprisingly, she actively participated in three more competitions involving at least 20 short-track speed skating rounds during this period. This discomfort persisted for an extended 29-day duration after the incident, leading to an MRI being conducted at a different hospital than ours. The radiologist at the external facility reported an old C2 Durel Type II, Subclass C fracture (Figure 1). Ongoing pain led the radiologist to refer the case to our department. Upon the patient’s arrival at our institution 41 days after the injury, the clinical presentation, recent accident history, and the extent of the fracture, which involved approximately one-third of the odontoid diameter, raised suspicions of a fresh fracture related to the accident. Subsequently, we performed a CT scan and a functional cervical spine CT, both of which confirmed the instability of the C2 Durel Type II, Subclass C fracture. The functional CT examination revealed a 5 mm movement in the fracture line (Figure 2). On the 45th day after the initial injury, the patient underwent a successful surgical procedure, utilizing intraoperative O-arm CBCT and Stealth Station Navigation System (SS8) for C1-C2 dorsal fusion, where we placed bi-lateral screws in the lateral masses of both C1 and C2 and connected them with a rod (Figure 3). This surgical intervention led to the successful repositioning and stabilization of the C1 odontoid (Figure 4). Following the surgical procedure, the patient embarked on a comprehensive rehabilitation program starting six weeks post-surgery. By the 12-week mark post-surgery, she had made a remarkable recovery, regaining full functionality, and was actively participating in speed skating training without experiencing any complaints. Now, 9 months after the incident, she was granted the medical clearance to be called to represent her home country in the following international ice-skating competition due to her amazing speedy recovery. In a broader context, it is noteworthy that over 14 years, from February 2009 to February 2023. Among 347 cases of C2 odontoid fractures, only 5 fractures (1.14%) in our institute were attributed to professional sports activities. These sports-related fractures encompassed cases linked to skiing, short-track speed skating, cross-motorcycling, and go-karting. Notably, 3 of these fractures occurred during winter sports. Different treatment modalities were employed for these cases, with ventral odontoid screw fixation used in two instances, dorsal C1-C2 screw fixation in 1 case, and the HALO fixation device employed in the remaining 2 cases. In general, evaluating an acute cervical spine injury is challenging. Clinicians recommend obtaining three distinct views of the cervical spine. These views encompass the anteroposterior, cross-table lateral, and open-mouth odontoid cervical radiographs [1,2]. However, due to the inherent limitations of conventional plain radiography, the standard approach has evolved to encompass the more widespread utilization of flexion/extension radiographs, CT scans, and MRI examinations, particularly for detecting subtle cervical spine injuries [3]. CT scans have emerged as the modality for effectively visualizing the cervical spine. Consequently, when CT imaging is deemed necessary, there is often no prerequisite for additional plain radiographic imaging [4]. Recent empirical data has suggested that CT imaging should be prioritized to assess the cervical spine rapidly and efficiently, potentially rendering conventional plain radiographic imaging unnecessary [5]. Moreover, in specific clinical scenarios such as neurologic deficits, the need to assess ligamentous injuries, or the imperative to rule out underlying pathologies, MRI may also be considered an invaluable diagnostic tool [6,7]. In light of the absence of clear-cut guidelines regarding the optimal imaging modality for cervical fracture diagnosis, healthcare professionals must thoroughly understand the strengths and limitations of each option. In athletic events, continuous video recording can offer invaluable insights into the injury’s nature, assisting clinicians in making an informed choice regarding the most suitable imaging technique. The selection of an imaging method plays a pivotal role in determining the accuracy and speed of diagnosis, ultimately affecting patient outcomes. While CT and MRI remain the foundations of cervical fracture diagnosis, clinicians must adopt a holistic approach. This involves relying on imaging results and considering the clinical presentation, mechanism of injury, and any associated symptoms [8,9]. The synergy between the patient’s anamnesis, clinical picture, and imaging modalities ensures a comprehensive evaluation, minimizing the risk of misdiagnosis. As the field advances, ongoing research and collaboration between radiologists, neurosurgeons, and orthopedic specialists will be crucial in refining diagnostic protocols ensuring that patients receive timely and appropriate care.
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Figure 2. Functional cervical spine CT images: (A) Axial view; (B) Coronal view; (C) Sagittal view. The fracture is highlighted by the space between the 4 axes lines.
Figure 2. Functional cervical spine CT images: (A) Axial view; (B) Coronal view; (C) Sagittal view. The fracture is highlighted by the space between the 4 axes lines.
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Figure 3. O-arm CBCT cervical spine images: (A) Axial view; (B) Coronal view; (C) Sagittal view. The fracture is highlighted by the space between the 4 axes lines.
Figure 3. O-arm CBCT cervical spine images: (A) Axial view; (B) Coronal view; (C) Sagittal view. The fracture is highlighted by the space between the 4 axes lines.
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Figure 4. Post-Operative cervical spine X-ray: Screw Placement in C1 and C2 Lateral Masses—(A) Coronal View, (B) Sagittal View.
Figure 4. Post-Operative cervical spine X-ray: Screw Placement in C1 and C2 Lateral Masses—(A) Coronal View, (B) Sagittal View.
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Author Contributions

Conceptualization, Á.V. and M.W.A.-S.; Methodology, Á.V., M.W.A-S, and I.K.; Data Curation, I.K. and S.V.; Long-term Follow-up: Á.V.; Writing—Original Draft Preparation, M.W.A.-S., and S.V.; Writing—Review and Editing, M.W.A.-S.; Supervision, Á.V. All authors have read and agreed to the published version of the manuscript.

Funding

External funding was not provided for this research.

Institutional Review Board Statement

Not applicable.

Informed Consent Statement

Informed consent was obtained from all subjects involved in the study.

Data Availability Statement

All data generated or analyzed during this study are included in this published article.

Acknowledgments

We wish to extend our heartfelt appreciation to the dedicated team at the Department of Neuro-surgery and Neurotraumatology within Péterfy Hospital—Manninger Jenő National Trauma-tology Institution located in Budapest, Hungary.

Conflicts of Interest

The authors affirm that there were no financial or commercial affiliations that could be regarded as potential conflicts of interest in the course of this research.

References

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