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Characteristic Volatile Compounds of Phlomoides rotata (Benth. ex Hook. f.) Mathiesen and Their Potential Anti-oxidant ActivitiesCitation: To be added by editorial staff during production
Version 1
: Received: 30 October 2023 / Approved: 30 October 2023 / Online: 31 October 2023 (05:18:01 CET)
Version 2
: Received: 31 October 2023 / Approved: 31 October 2023 / Online: 31 October 2023 (09:01:09 CET)
How to cite:
Pan, Z.; Xie, C.; Yan, X. T.; Su, Y. M.; Haq, A. U.; Wang, J. Characteristic Volatile Compounds of Phlomoides rotata (Benth. ex Hook. f.) Mathiesen and Their Potential Anti-oxidant ActivitiesCitation: To be added by editorial staff during production. Preprints2023, 2023101959. https://doi.org/10.20944/preprints202310.1959.v1
Pan, Z.; Xie, C.; Yan, X. T.; Su, Y. M.; Haq, A. U.; Wang, J. Characteristic Volatile Compounds of Phlomoides rotata (Benth. ex Hook. f.) Mathiesen and Their Potential Anti-oxidant ActivitiesCitation: To be added by editorial staff during production. Preprints 2023, 2023101959. https://doi.org/10.20944/preprints202310.1959.v1
Pan, Z.; Xie, C.; Yan, X. T.; Su, Y. M.; Haq, A. U.; Wang, J. Characteristic Volatile Compounds of Phlomoides rotata (Benth. ex Hook. f.) Mathiesen and Their Potential Anti-oxidant ActivitiesCitation: To be added by editorial staff during production. Preprints2023, 2023101959. https://doi.org/10.20944/preprints202310.1959.v1
APA Style
Pan, Z., Xie, C., Yan, X. T., Su, Y. M., Haq, A. U., & Wang, J. (2023). Characteristic Volatile Compounds of <em>Phlomoides rotata</em> (Benth. ex Hook. f.) Mathiesen and Their Potential Anti-oxidant ActivitiesCitation: To be added by editorial staff during production. Preprints. https://doi.org/10.20944/preprints202310.1959.v1
Chicago/Turabian Style
Pan, Z., Anwar Ul Haq and Jian Wang. 2023 "Characteristic Volatile Compounds of <em>Phlomoides rotata</em> (Benth. ex Hook. f.) Mathiesen and Their Potential Anti-oxidant ActivitiesCitation: To be added by editorial staff during production" Preprints. https://doi.org/10.20944/preprints202310.1959.v1
Abstract
Due to the low content, few studies are focused on the volatile compounds of Phlomoides rotata (Benth. ex Hook. f.) Mathiesen (PR, syn. Lamiophlomis rotata (Benth.) Kudô). However, such volatile compounds may have important pharmacological activities such as antioxidant, anticancer. In order to identify the chemical markers (CMs) in the essential oils (Es) and explore the potential bioactivities, we first conduct a thoroughly investigation on the volatile compounds and evaluate their anti-oxidant activities (AOAs), to the best of our knowledge. Light yellow Es with a fresh and elegant smell are obtained by hydro-distillation with an average yield of 0.11% (mL/g). After separation through cryoprecipitation, the crystals (Cs) and EOs removed crystals (RCs) were gotten, respectively. A total of 81 components are qualified and quantified in the Es, Cs and RCs, in which 44 ones are first reported from PR. As for content, the main compounds are long-chain fatty acids (LCFAs) and their esters. Among them, palmitic acid (PA), myristic acid (MA), linoleic acid (LA), oleic acid (OA) and methyl palmitate are highlighted, Besides, hexahydrofarnesyl acetone and phytol are also prominent Four kinds of C13-norisoprenoids are first reported from PR, in which, trans-β-damascenone is potent in flavour. In sum, these eight representative compounds can be chosen as the CMs. The AOAs of Es, Cs, RCs and four CMs such as PA, MA, LA and OA are evaluated by in vitro assays. In general, PA and MA present pro-oxidant activities (POAs) or weak AOAs. LA and OA show POAs or weak AOAs in lower concentration group, whereas demonstrate medium or strong AOAs in higher concentration group. Usually, the RCs demonstrate stronger AOAs and the Cs present weaker AOAs compared with those of the corresponding Es, which should be related to their different content of PA. This study can give some hints on the utilization of such Es which are abundant in LCFAs.
Medicine and Pharmacology, Medicine and Pharmacology
Copyright:
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